To restore normal intestinal motility, a combination therapy is indicated, including a special diet and medication. One of the most popular drugs of domestic production are Trimedat tablets, analogues of which are represented by substances based on trimebutin. The tool has a number of features that you should familiarize yourself with before taking it.
Material Content:
Composition (active substance) and properties of Trimedate
The active substance of the drug is trimebutin maleate, in an amount of 100 or 200 mg in one tablet. As auxiliary and forming components in the production of using lactose, starch, silicon dioxide and magnesium stearate. Appearance depends on the dosage of pills: 100 mg - white flat cylinders with extruded abbreviation of the active substance on one side, 200 mg - white, round and convex in both directions.
Tablets are packaged in blisters of 10 pieces. In one cardboard pack - three convolutes and official instructions for use.
The main properties of this drug:
- normalization of intestinal motility;
- improvement of the digestive system;
- relief of spasm in intestinal hyperkinesis.
The drug is used for various diseases of the gastrointestinal tract associated with impaired peristalsis and normal physiological activity of muscles.
Indications for use of the drug
The list of indications for the use of tablets is quite large, but most often a drug based on trimebutin is prescribed for the treatment of irritable bowel syndrome and dyspeptic disorders, manifested by pain, cramping and obstruction. Tablets should be used to normalize motor function after surgical operations on the digestive tract.
Due to the antispasmodic effect, Trimedat tablets are indicated for use in gastrointestinal tract hyperkinesis. In this case, taking the drug quickly eliminates cramping and pain, improves the response of the intestine to food irritants, and facilitates the process of defecation.
Due to the nature of the action of the drug, it is often prescribed for prophylaxis before examinations (X-ray and endoscopy of the digestive tract). Taking the medicine in a short course in this case helps to better visualize the condition of the internal organs.
Trimebutin-based medication is used to treat both adults and children, but in different dosages. In pediatrics, this active substance is used to treat dyspepsia, which develops against the background of impaired intestinal motility.
Instructions and dosage
Instructions for use contain universal recommendations on the dosing schedule, which can be changed at the discretion of the attending physician.
The following recommended dosages are given in the official instructions:
- adolescents (over 12 years old) and adults: 1 tablet three times a day;
- children 5-12 years: 50 mg (½ tablets in the minimum dose) 3 times a day;
- children 3-5 years: 25 mg three times a day.
Teens and adults can be prescribed as 300 mg of the drug per day, and 600 mg of the drug, which depends on the indications. The duration of admission is determined by the doctor individually for each patient.
The drug in a dosage of 100 mg of active substance in one tablet is a children's form of release of the drug intended for patients older than three years.
Young children are not prescribed the drug due to the lack of data on the safety of its use in this age group.
Contraindications and side effects
Contraindications of the drug are up to three years of age and individual intolerance of the active substance. And it should also be borne in mind that the tablets contain lactose, therefore, for some people, taking may be contraindicated.
In the first trimester of pregnancy, the medicine can not be used. The decision on the safety of the use of tablets in the second and third trimester is made by the doctor, and depends on the ratio of risk to the fetus and the health benefits of the mother.
There is insufficient data on the safety of using the product during lactation, therefore it is recommended to refrain from taking tablets to normalize the digestive tract or to stop breastfeeding during treatment.
In the vast majority of cases, the medicine is well tolerated and does not cause negative reactions of the body. The only reported side effects are skin allergic reactions, manifested by the formation of a rash, erythema, redness and itching of the epidermis.
Cheap analogues of Russian production for adults
Trimedat is a Russian drug and is manufactured by Valenta Pharma. The cost “bites” a little - about 500 rubles per pack of medicine in a dosage of 200 mg. Since the drug is often prescribed for a long time, many patients prefer to replace the tablets with cheaper Russian analogues of Trimedat.
It is difficult to choose the full compliance with the original on the active substance. The only drug that you can choose to replace is Neobutin tablets. The medicine is also produced by a domestic pharmaceutical company, but the price difference is not noticeable - Neobutin costs about 200 rubles for 10 tablets in a dosage of 100 mg. Thus, the acquisition of Trimedat is more profitable, because for 500 rubles the buyer receives as many as 30 tablets in an increased dosage.It should be noted that tablets of 200 mg of the active substance can be divided in half without the risk of worsening therapeutic effect.
Neobutin in a dosage of 200 mg is rarely found in pharmacies, but the price for 30 tablets is lower than the cost of the same amount of Trimedat - about 400 rubles per pack.
If the drug is prescribed for the treatment of irritable bowel syndrome, you can replace it with tablets or capsules Duspatalin. This medicine contains another active substance - mebeverin, but is produced by an American pharmaceutical company. The Russian analogue is Sparex capsules. Their cost is about 350 rubles per package.
If trimebutin intolerance, you can replace the medicine with the drug Ganaton. This is a medication based on itopride, which has no Russian analogues. The drug is recommended for conditions accompanied by a decrease in the tone of the gastrointestinal tract and deterioration of intestinal motility. Cost - about 400 rubles per package.
It can be seen that it is difficult to select domestic analogues, besides there is no particular difference in cost, therefore, the search for substitutes is not practical. The exception is only cases of individual intolerance to the main active substance.
Similar drugs for children
Trimedate for children is a tablet in a dosage of 100 mg. They can be divided into 2 and 4 parts, depending on the prescribed dosage. Replace the medicine for the child with Neobutin with a content of 100 mg of active substance in one tablet.
In general, it is recommended to trust the pediatrician when prescribing medication for the baby. Like Trimedat, Neobutin is not prescribed for children under three years of age. If necessary, the doctor will be able to advise analogues cheaper, depending on the age of the patient and the indications for prescribing the medicine.
- Manyunya
- Irina