Trimedat tablets are an effective antispasmodic that increases the motility of the digestive tract. The main effect of the drug has on the conductivity of the intestine, the remaining elements of the digestive system are less susceptible to active components. Indicated for the treatment of pain in the abdomen and digestion disorders.

Composition of the tablets

The drug has a single form of release - tablets. In pharmacies, Trimedat is sold containing 100 or 200 mg of the active substance. The amount of the drug in one package varies from 10 to 30 pieces (10, 20 and 30 units of medication, respectively). The drug is 100 mg for children. Moreover, for a child weighing less than 40 kg, 1 tablet is divided into several doses (½ or ¼ part).

The structure of Trimedat includes:

  • Trimebutin (base active ingredient);
  • magnesium silicate with hydroxyl;
  • lactobiosis;
  • fumed silica;
  • stearic acid;
  • corn flour.

The drug does not contain dyes, so the tablets are white. To protect against fakes, the medication is equipped with the engraving "TM". To facilitate the breakdown of the drug into smaller doses, there is a special risk in the center.

Pharmacological action, pharmacodynamics and pharmacokinetics

The drug has a double pharmacological effect on the digestive tract. With excessive tissue activity, trimebutin behaves as an antispasmodic.If there is a lack of intestinal motility, then the medication causes an increase in the activity of peristalsis.

Thanks to the normalization of wave-like movements, processed food in the right rhythm goes all the way to the anus. In addition, Trimedat stimulates the process of wetting food debris with juice, which is used for processing nutrients.

The drug has a local anesthetic effect, which allows not only to normalize the digestive tract, but also to relieve pain and cramping in the abdomen.

After administration, the highest concentration of active substances in the blood is observed after 1 hour. Processing of drug components occurs in the liver, decay products are excreted together with urine after a day.

Why is Trimedat prescribed?

The spectrum of use of the drug is a violation of the normal functioning of the stomach, biliary tract and intestines.

Gastroenterology practices the appointment of Trimedat in the following pathological conditions:

  • difficult and painful digestion;
  • heaviness in the stomach;
  • premature saturation;
  • gagging;
  • irritable bowel syndrome;
  • abdominal syndrome;
  • cuts in the stomach;
  • excessive gas formation;
  • violation of the bowel movement;
  • GERD.

As well as Trimedat tablets are used in restorative postoperative therapy aimed at treating bowel obstruction.

Instructions for use and dosage

Take Trimedat tablets can adults and children from 3 years, but in different quantities. The annotation to the drug indicates that the amount of use depends on the age of the patient and the disease diagnosed by a specialist. The maximum dosage for an adult is 600 mg of Trimedate per day, which corresponds to 3 tablets with 200 mg of the active substance or 6 tablets of 100 mg. The minimum daily amount of the drug for an adult patient is 300 mg.

The dosage for children under 5 years of age is 25 mg of trimebutin. An older child (5 to 12 years old) can be given a larger amount of the drug - 50 mg.

To facilitate and accelerate the absorption of active components, the use of the drug must be accompanied by sufficient drinking. The optimal time for admission is thirty minutes before or after a meal.

When diagnosing chronic irritable bowel, the duration of therapy after the disappearance of the main symptoms is extended by 3 months to avoid exacerbations.

During pregnancy and lactation

The spectrum of the effect of the drug on the female body is such that the active components do not penetrate the histohematological barrier. Studies of the drug did not establish a possible negative effect on the development of the embryo. However, the clinical safety of Trimedate during pregnancy and lactation has not been proven.

Nevertheless, in some cases, doctors allow the possibility of prescribing a drug during breastfeeding, as well as in the second and third trimester. But this is done only in cases where the effect of taking exceeds the potential risk to the child.

Drug interaction

In the instructions that are attached to the drug, there is no information about the drug interaction with other medicines. There are no data on substances that can enhance or weaken the effects of trimebutin on the digestive organs.

Doctors believe that the simultaneous administration of other antispasmodic drugs with Trimedat leads to an increase in the action of the active component.

Alcohol Trimedate Compatibility

Although official studies of the interaction of the drug and alcohol-containing products have not been conducted, gastroenterologists categorically exclude the possibility of combining them. A similar point of view is based on the fact that trimebutin normalizes the motility of the gastrointestinal tract. Alcohol, on the contrary, stimulates the release of juices that break down nutrients, and causes excessive intestinal activity.Thus, alcohol negates the effect of the drug.

Contraindications, side effects and overdose

Despite the effectiveness established by practice, Trimedat, in some cases its use is contraindicated, because it can cause poor health.

Medication is prohibited in the following cases:

  • individual intolerance to one of the substances that make up the drug (including lactose allergy);
  • early childhood (up to 3 years);
  • acute or chronic toxic megacolon;
  • early pregnancy (due to increased load on the liver and the resulting toxicosis that are characteristic of this period);
  • syndrome of partial or complete violation of patency of the digestive tract.

According to statistics, Trimedat is well tolerated by patients, however, manufacturers warn of adverse reactions of the body that may follow after taking the drug.

Possible negative consequences of the use of an antispasmodic:

  • skin rashes;
  • pain in the epigastrium or hypochondrium;
  • violation of the normal defecation process (usually occurs when the recommended dosage is not followed);
  • urinary retention;
  • dryness and bad taste in the mouth;
  • nausea;
  • craving for sleep and general fatigue;
  • migraine;
  • dizziness;
  • painful tides in the area of ​​the mammary glands;
  • menstrual failure.

Medical statistics indicate that a negative reaction to Trimebutin from the central nervous system is extremely rare.

In case of drug overdose, the likelihood of side effects increases significantly. There are no medications that can remove the active components from the body. In such cases, only gastric lavage helps.

Analogues of the drug

The pharmaceutical industry offers customers along with Trimedat many medicines that have a similar spectrum of action on the body.

Moreover, there are two options:

  • Trimedat tablets analogues, having a composition different from the original, but with a similar algorithm of exposure to the body;
  • structural analogues (or synonyms), which contain the same substances as the original drug.

Among the synonyms the most popular are Trimedat Valenta, Neobutin, Debridat.

Medicines are considered similar:

  • Iberogast drops;
  • Spasmomen and Dycetel (in tablet form);
  • capsules and Pepsan-R gel;
  • capsule form of Duspatalin, Sparex, Enterosan and Niaspam;
  • Colofort absorbable tablets;
  • powder for the preparation of Smecta solution;
  • Trigan injection solution.

Despite the fact that analogues have a similar algorithm of action on the body, there are significant differences in contraindications and side effects. Therefore, the decision to replace one drug with another can only be made by a qualified specialist.

The antispasmodic Trimedat has established itself as a reliable medication for the relief of impaired motor function of the intestine and other digestive organs. It has few contraindications and is characterized by a low probability of side effects.

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