Polyoxidonium acts as a new immunomodulator and antioxidant, which carries out several mechanisms of exposure, while increasing the body's resistance to various infections. However, before taking, you should read the instructions for use of Polyoxidonium tablets.
Material Content:
Description of the release form and composition
The main active compound of the drug is azoximer bromide.
For convenience, Polyoxidonium is prescribed to patients for the treatment of various diseases in several variable forms of use:
- Polyoxidonium tablets 12 mg;
- suppositories 6 and 12 mg;
- lyophilisate for the preparation of an injection solution of 3 and 6 mg.
Additional compounds present in the composition of the drug include: povidone, betacoraten, mannitol, lactose monohydrate, steric acid. These substances are classified as auxiliary, they do not have a therapeutic effect.
What helps Polyoxidonium tablets
Polyoxidonium has a moderate immunostimulating effect, while reducing the manifestation of an immunodeficiency state. In this case, there is a significant increase in the body's resistance to infections. And also, the medication has antioxidant properties, thanks to which a detoxifying effect is possible.
The main chemical compound has a direct effect on the process of antibody formation.
In secondary immunodeficiencies, this drug is used to increase the effectiveness of treatment and helps to reduce the duration of therapy. Thanks to this medicine, the need for the use of antibiotic drugs, bronchodilators and glucocorticosteroids is reduced for patients. A fairly good tolerance and assimilation is due to the fact that the drug does not have carcinogenic, allergenic, toxic, mutagenic or teratogenic activity.
It is also worth noting that Polyoxidonium is able to activate the bactericidal property of saliva. After internal administration, lymphoid cells of the lymph nodes of the digestive tract are activated. As a result, the protective functions of the body to infectious agents are significantly enhanced. The form of a suppository or intravenous solution is extremely popular for the restoration of immune protection after secondary immunodeficiencies that were caused by burns, malignant tumors, injuries or various infections.
Due to the high molecular weight structure, this medication is often prescribed to remove heavy metals or toxins from the body. As a result, the severity of signs of intoxication of the body decreases and the pain syndrome stops.
With complex therapy, an immunomodulator is able to reduce adverse reactions while taking other drugs.
Based on the pharmacological properties, it is advisable to prescribe this therapeutic agent in such cases:
- viral or bacterial lesions of acute or chronic course;
- complicated ARI for arthritis;
- for accelerated tissue regeneration (burns, injuries);
- in the postoperative period to prevent the development of infectious complications;
- tuberculous process;
- cancer patients, as well as to minimize the effects of radiation therapy and drugs with hepatotoxic effect;
- allergic diseases of acute or chronic course, which were complicated by infections of a bacterial nature;
- bronchial asthma complicated by infectious pathologies;
- chronic viral diseases of the urinary system;
- in cases of inflammatory processes of an infectious nature in the oropharynx;
- with viral or bacterial etymology of inflammatory lesions of the genitourinary system;
- in combination with other medicinal medicines to strengthen and enhance the body's immune defense.
Often, this medication is used for preventive purposes, as well as for the correction of immunodeficiency states that are directly related to the natural aging process.
Instructions for use and dosage for adults and children
Depending on the medical history and other individual indicators of the patient, the specialist selects the optimal course of therapeutic treatment. In the instructions for use, the recommended dosages will be given, as well as the duration of the drug. However, the use of Polyoxidonium tablets must be agreed with a specialist. In some cases, a repeat of the therapeutic course may be required after 3 months.
It is allowed to take Polyoxidonium in tablets orally (without chewing, swallow) or sublingually (dissolve under the tongue until completely dissolved). The standard regimen is two tablets per day half an hour before meals. Children under 10 years of age can be prescribed ½ tablet.
In other cases, the dosage, duration and treatment regimen directly depends on the diagnosis:
- With chronic tonsillitis, Polyoxidonium for adults and children from 12 years of age is prescribed one thing three times a day. Continue treatment for at least 10 days.
- Diseases of the upper respiratory tract in a chronic course are treated according to the scheme: one tablet for children and two for adults. The course of therapy is from a week to two.
- In the case of chronic sinusitis and otitis media, one tablet should be taken twice a day. The patient requires continuous treatment for up to 10 days.
- With severe inflammatory processes in the oral cavity caused by bacteria or fungi, one tablet is shown three times a day. And you should also observe equal time intervals between receptions. The duration of therapy is 15 days.
- For the prevention of acute respiratory infections during periods of seasonal epidemics and diseases, it is recommended to take 2 tablets per day, for adolescents - one each. The course of treatment lasts 10 days.
- During therapeutic treatment of recurrent herpes of the nasal or labial region, adult patients are recommended to take the drug one tablet twice a day. The duration of the course does not exceed 10 days. Children with the same disease will need half a tablet twice a day. The duration of treatment in this case does not exceed one week.
- In order to treat an allergic disease, which was complicated by a fungal nature, viruses or bacterial infection, one tablet should be taken twice a day.
But also pills to increase immunity are often prescribed for the prevention of secondary immunodeficiency. For this, adults should take one tablet for ten days.
During pregnancy and lactation
Any dosage form of Polyoxidonium is not recommended for use during pregnancy, as well as breastfeeding. This limitation is due to the fact that no studies have been conducted to date that confirm complete safety for a pregnant woman. For therapeutic treatment during lactation, the question of the abolition of breastfeeding should be decided, since the main active compound is able to be excreted together with breast milk.
Drug interaction
It is important to indicate that this drug is quite well combined with most medications, including antibiotic, antiviral, antifungal, antihistamines, as well as cytostatics, glucocorticosteroids and bronchodilators. However, it should be borne in mind that a solution for parenteral administration is not recommended to be diluted with an infusion liquid that contains proteins.
Contraindications, side effects and overdose
According to the instructions for use, there are a number of contraindications to this remedy, as well as age restrictions.
Before starting therapeutic treatment with Polyoxidonium, you should carefully read the following list of absolute prohibitions:
- Patients with increased susceptibility to the main component of the active composition of the drug.
- The period of pregnancy and lactation.
- Lactose deficiency or intolerance.
- Patient age up to 6 months for lyophilisate.
- The age of the child is up to 12 years for a tablet form.
- Children under 6 years of age for rectal suppositories.
Patients who have functional impairments in the functioning of the renal system need to take this medicine with caution, as well as carefully monitor the performance of the tests. This drug is characterized by a good reaction of the body.
Patients, as a rule, do not experience adverse reactions after use.
Among the side effects, only painful sensations after intramuscular administration of the drug are present. There were no cases of overdose.
Analogs Polyoxidonium tablets
It is impossible to select an identical substitute for structural composition, however, there are a number of drugs that almost completely coincide with Polyoxidonium in pharmacological properties and the mechanism of action.Similar drugs according to this criterion are the following: Broncho-Vaxom, Neuroferon, Florexil, Glutaxim, Vilozen, Anaferon, Immunal, Herbion. Before switching to Polyoxidonium analogues, it is necessary to consult a physician.
