Mildronate tablets restore metabolic processes. Against the background of their intake, oxygen saturation of tissues improves, toxic substances are eliminated. The medication is prescribed for increased physical exertion, during intense mental work, in the post-infarction, post-stroke periods.

Release forms and composition

Mildronate is a product of a Latvian pharmaceutical company, available in the following forms:

  • capsules;
  • pills
  • injection solution.

A medication consists of an active ingredient, meldonium.

In addition to it, Mildronate 250 Tablets consist of the following inactive ingredients:

  • povidone;
  • silica;
  • mannitol;
  • magnesium stearate;
  • potato starch.

Mildronate capsules consists of the following inactive components:

  • calcium stearate;
  • titanium dioxide;
  • gelatin;
  • silica;
  • potato starch.

Auxiliary components do not have a therapeutic effect on the patient's body. They are used to give the necessary shape and better digestibility of the active ingredient.

Pharmacological properties and pharmacokinetics

The active component of Mildronate is considered a substitute for the substance found in all cells of the human body. A metabolic agent is responsible for the balance between how much oxygen the cells need and how much they get.It provides a protective and tonic effect.

Against the background of treatment with this medication, an early restoration of energy reserves occurs. A person can withstand great physical exertion. Mildronate is used for disorders of the cardiovascular system, with oxygen starvation of the brain.

Taking the drug for ischemia can slow down the process of necrosis formation. In humans, rehabilitation is significantly reduced. Treatment of cardiac pathologies with Mildronate allows to achieve an increase in contractility of the heart muscle, the severity of angina pectoris decreases, and tolerance to stresses increases.

Treatment of cerebral blood circulation improves microcirculation in the ischemic focus. There is a dislocation of blood in the area affected by ischemia. The drug has proven effective in dystrophic foci of the fundus. While taking this drug, the condition of a patient with chronic alcoholism improves.

The maximum amount of active substance is formed in the blood an hour after its use. The metabolic process occurs in the cells of the liver. The medicine is excreted through the urinary system.

What is Mildronate prescribed?

This medicine is often prescribed as part of the complex treatment of certain diseases.

Indications for use of Mildronate:

  • heart failure;
  • chronic fatigue;
  • stroke;
  • chest pain
  • cardiac disharmony;
  • myocardial infarction;
  • a period of increased mental stress;
  • period of increased training, competition among athletes;
  • alcoholism;
  • cardiomyopathy;
  • retinopathy
  • Ischemic heart disease;
  • cerebrovascular insufficiency.

The drug is widely used during high physical activity in athletes. This drug allows them to prevent overstrain of the heart muscle, thereby avoiding problems with the development of cardiac pathologies.

Instructions for use of the drug

Instructions for use describe in detail at what dosage this or that form of Mildronate is taken for various diseases. For all types of the drug, one rule applies: you can not take the medicine or give injections after 5 pm. Since the active substance of the drug enhances psychomotor agitation, and the patient has difficulty falling asleep.

Mildronate in ampoules is placed intravenously. In rare cases, the solution is injected into the muscle, as injections are painful and can cause an allergic reaction.

An injection is usually prescribed as follows:

  • heart attack, angina pectoris require a single injection of a drug of 500-1000 mg based on the patient's condition;
  • with impaired blood circulation of the brain, they put 500 mg once a day;
  • in case of chronic cerebrovascular accident, a 3-time administration of 500 mg per day is prescribed.

For the treatment of vascular pathologies of the fundus, 0.5 ml of the drug is injected into the muscle of the eye once a day - 10 days.

Mildronate tablets are prescribed as follows:

  • with ischemia, heart failure, cardiomyopathy, the daily dose varies from 0.5 g to 1 g. The required dosage can be taken at one time, you can divide it by 2 times. This aspect is discussed with the attending physician;
  • in case of impaired blood circulation of the brain, the recommended dose is 500 mg. If the patient suffers from a severe disorder, then it can increase to 1 g. The medicine is drunk at a time, and is also divided into 2 doses;
  • with reduced working capacity, excessive physical, mental stress, it is indicated to drink 500 mg twice a day. The treatment course lasts 10 days. If necessary, it is possible to extend the course after a month;
  • with alcoholism, tablets are prescribed four times a day for 500 mg a weekly course.

The usual therapeutic course in tablet form is 6 weeks. If necessary, the treatment can be repeated.Up to 3 courses are allowed per year.

Note! Athletes in preparation for the competition are prescribed 500 mg once a day - 2 weeks. During the competition, 500 mg per day is drunk for 10 days.

During pregnancy and lactation

Due to the lack of data on the use of Mildronate during pregnancy, breastfeeding, the medication is not prescribed for pregnant or lactating women.

Drug interaction

Mildronate combines well with many medications.

However, this drug should be carefully taken in parallel with the following medicines:

  • antihypertensive, coronary dilating drugs enhances the effect of these funds;
  • nitroglycerin may develop tachycardia;
  • cardiac glycosides possibly a sharp drop in blood pressure to extreme borders.

To avoid unwanted reactions from the body, any combination of medications should be reported to the attending physician.

Contraindications, side effects and overdose

Mildronate, like any medicine, has a number of contraindications.

These include the following conditions:

  • osteochondrosis of the cervical vertebrae;
  • renal, liver failure;
  • individual intolerance;
  • pregnancy;
  • lactation;
  • brain oncology.

As a result of taking Mildronate, the development of the following adverse reactions from the body is possible:

  • rashes on the skin;
  • itching
  • Quincke's edema;
  • hyperemia of the skin;
  • tachycardia;
  • lowering blood pressure;
  • mental overexcitation;
  • fatigue
  • burping;
  • diarrhea
  • increased gas formation.

If side effects occur, you should immediately stop taking Mildronate and consult a doctor.

Cases of overdose can be manifested by a decrease in blood pressure, headache, weakness, dizziness, and an attack of tachycardia. Overdose therapy consists in the use of symptomatic drugs.

Analogues of the drug

It is necessary to select an analog of Mildronate only after consultation with your doctor.

The following substitutes are usually recommended:

  • Idrinol, which is prescribed to improve metabolic processes in the post-stroke, post-infarction periods. Available in injection;
  • Cardionate is used for chronic alcoholism, stroke, after heart surgery. It is published in capsules, ampoules;
  • Mediterns in capsules is aimed at accelerating metabolic processes, increasing physical abilities. It treats alcohol addiction, heart failure;
  • Mildroxin is used to get rid of angina pectoris, improves cerebral circulation;
  • Meldonium is aimed at restoring metabolism, treats heart diseases, and alleviates alcohol intoxication.

Choosing analogues of Mildronate, you should carefully read the instructions for use. Since some drugs have a large number of side effects.

What is better pills or injections Mildronate

Many patients are wondering if it might be better to be treated with Mildronate injections to achieve the greatest effect. Typically, an injection of the drug is prescribed in the more acute stage of the disease. After improvement of health in the conditions of outpatient treatment, Mildronate therapy in tablets is used. Therefore, the doctor, based on the patient’s condition, his age, prescribes the necessary form of the drug. Moreover, the tablet form gives fewer allergic reactions than the injection.

Mildronate is a modern drug that successfully treats metabolic disorders, improves oxygen saturation of the body.

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