Suprastin: instructions for use for children and adults, release form, composition, analogues of the drug for allergies

The highly effective drug Suprastin or Chloropyramine is prescribed to prevent, as well as eliminate the signs of allergies. The medicine has a quick effect and thereby reduces the unpleasant symptoms of the disease. But therapy with the drug should be carried out strictly according to the instructions, since ignoring the intake standards can significantly aggravate the situation.

Composition and release forms

Suprastin is available in tablet form (25 mg each) and as a clear solution for injection (20 mg each). The main component of the drug is chloropyramine hydrochloride. In addition, the composition contains auxiliary components that improve the distribution of the basic substance.

The composition can be supplemented with stearic acid, gelatin, talc, lactose monohydrate, lactose.

Packing of the tablet form occurs in blisters of 10 pieces, and ampoules - of 5 pieces.

Pharmacological action, pharmacodynamics and pharmacokinetics

Histamines are biologically active components that accumulate in mast cells, connective tissue. In the normal state of a person, they are in a sleeping state. But as soon as the cell membrane is damaged by the action of an allergen, they begin to be actively produced, thereby giving an alarming signal about the penetration of a foreign substance into the body.It is this reaction that the drug stops, which helps to reduce the unpleasant symptoms of allergies.

Chloropyramine is a chlorinated duplicate of trypelenamine, which belongs to the 1st generation of antihistamines.

The principle of action of Suprastin is to slow down the production with subsequent blocking of histamine H1 receptors.

After the active component enters the body, its rapid absorption in the digestive tract occurs. And after 15-30 minutes, the person feels relief. The maximum concentration of a substance in the blood is observed after 1 hour. The duration of the therapeutic effect is 3-6 hours.

Chloropyramine metabolism occurs in the liver, so patients suffering from impaired function of this organ need to adjust the medication norm. The substance is excreted in the urine. This process is faster in children.

The elimination of chloropyramine is slowed in case of kidney failure.

What is Suprastin prescribed for?

The medicine is used to stop the signs of allergies. The drug is prescribed for both adults and children.

The main indications:

• serum sickness;
• skin rashes;
• obsessive itching;
• seasonal rhinitis provoked by an allergen;
• bronchial asthma;
• hives;
• hay fever;
• conjunctivitis of allergic etiology.
• reaction to drugs;
• dermographism;
• food allergy;
• burn and ultraviolet radiation;
• inflammation caused by an insect bite;
• contact dermatitis.

The drug is also used in life-threatening conditions, such as Quincke's edema, anaphylaxis.

Instructions for use and dosage for children and adults

To stop the signs of allergy to go without complications, you must follow the instructions. Taking medication should be carried out no more than 4 times a day, with an interval of 6 hours.

The drug has a specific taste, so it must be drunk without damaging the integrity of Suprastin tablets, washed down with plenty of water. Reception is possible regardless of the time of eating. The full course of treatment is 5-7 days, but more precisely the information is voiced by the doctor.

Suprastin Tablets

This form of medication is taken orally. The norm per day for an adult is 75-100 mg, which is equivalent to 3-4 tablets.

It is permissible to use Suprastin for children from 3 years of age.

Admission rate for the child:

• 3-6 years - a quarter of the tablet twice a day;
• 6-12 years - half a tablet 2-3 times a day;
• from 12 years old - dosage is used as for an adult.

The dosage of admission can be slightly increased, but the reaction of the body should be monitored. The norm for children, according to the instructions for use, should be less than 2 mg per kg of body weight per day.

Therapy is stopped when all allergic symptoms are stopped.

In ampoules for injections

This form of medicine is used for injections. It is most important to use Suprastin ampoules for stopping a severe allergic reaction, manifested by anaphylactic shock, as well as Quincke's edema.

Initially, the drug is administered intravenously, and after stopping the shock, it is transferred to muscle injections or to the tablet form, with the improvement of the patient's condition. The duration of treatment is prescribed by the doctor. The standard dosage of Suprastin for adults is 1-2 ml per day.

For children, it is permissible to use Suprastin in ampoules from the 1st month of life. The norm depends on age: up to 1 year - 0.25 ml; 1-6 years - 0.5 ml; 6-14 years old - 0.5-1 ml. But the dosage per day for the total calculation should be less than 2 mg per 1 kg of the child’s weight. The child is injected with an insulin syringe, characterized by a long needle.

Suprastin also has a sedative effect, so after taking it, you should not drive a car and do work that requires an increased concentration of attention.

During pregnancy and lactation

It is categorically contraindicated to use Suprastin during gestation and lactation. The one exception is when an allergy threatens the life of the mother. But Suprastin is used in this case only in combination with hormonal drugs. This is an indication for premature termination of pregnancy, since the consequences can adversely affect the development of the fetus.

Chloropyramine is able to penetrate into milk, so the medicine should not be used during lactation. Ignoring this rule forms an immunopathy in a child and provokes the development of systemic pathologies.

Drug interaction

Patients taking other medications need to coordinate their combination with Suprastin with a doctor.

It is not recommended to combine the drug with:

• MAO inhibitors - increases the duration of the anticholinergic effect;
• sedatives, hypnotics, tranquilizers - the risk of side effects increases, and the simultaneous effect of two drugs is also enhanced;
• barbiturates - the metabolism of chloropyramine is accelerated, which weakens its therapeutic effect;
• tricyclic antidepressants - a depressing effect on the central nervous system is manifested.

The sedative effect of chloropyramine is neutralized by caffeine, and enhanced by clonidine.

Compatibility Suprastin with alcohol

Ethyl alcohol is able to enhance the depressive effect of the drug on the central nervous system. Therefore, during the period of Suprastin therapy, alcohol should be avoided, both in pure form, and as part of tinctures and other drinks.

Contraindications, side effects and overdose

Ignoring the norms of the drug causes an overdose. Sometimes it leads to death, especially if it concerns a child.

In this case, the following side effects occur:

• increased nervousness;
• tremor;
• vomiting
• anxiety;
• hallucinations;
• cramps
• heart palpitations;
• urinary retention;
• lack of coordination;
• visual impairment;
• fever;
• fatigue;
• drowsiness;
• dizziness;
• cramps
• lethargy.

The most dangerous consequences of an overdose are coma and cardiopulmonary collapse, which can cause patient death within 2-12 hours.

There is no special antidote to neutralize unpleasant symptoms. Therefore, the primary actions in case of an overdose are washing the stomach and taking activated charcoal.

Suprastin can also cause side effects, even if all dosage rules are observed in accordance with the age of the patient. When they appear, it is necessary to stop therapy, and consult with your doctor about the appointment of another drug with a similar effect.

Most likely side effects:

Name of authority or system	Characteristic symptoms
CNS	Drowsiness, apathy, dizziness, tremor, euphoria, headache
The cardiovascular system	Low blood pressure, tachycardia, palpitations
Organs of vision	Glaucoma, a sharp jump in intraocular pressure
Circulatory system	Agranulocytosis, hemolytic anemia, leukopenia
Musculoskeletal system	Myopathy
The immune system	Intrusive itching, rashes, urticaria, swelling
Urinary system, kidneys	Dysuria, urinary retention
Gastrointestinal tract	Impaired stool, vomiting, lack of appetite, nausea

Allergy drug analogues

To eliminate allergies, Suprastin analogues can also be used. Each of them has its own characteristics, which should be considered during therapy.

Analogs of Suprastin.

1. Tavegil - does not cause drowsiness, but is acceptable for use from 6 years.
2. Loratadine - the duration of the action is 24 hours, the restriction is the age of up to 2 years.
3. Diazolin is possible for young children, which allows you to protect the child during preventive vaccinations. But for an adult, its action may not be sufficient.
4. Zodak - completely duplicates the action of Suprastin.
5. Fenistil is acceptable for use during the period of gestation.

Using Suprastin for allergies, it is worthwhile to clearly understand that any self-medication can harm health. In addition, this medicine can only relieve the symptoms of allergies, and not completely relieve it. Only a doctor can identify an allergen by examining a patient.