Medicines that help get rid of problems with the gastrointestinal tract are appearing more and more every year. Reluctant to try new remedies on yourself, buy Omez (a certified medicine from India), proven and effective. Why appoint Omez, read on.
Material Content:
- 1 Composition and form of release
- 2 What is Omez assigned to?
- 3 Pharmacological action and pharmacokinetics
- 4 How to take the drug
- 5 Pregnancy and lactation
- 6 Drug interaction
- 7 Compatibility "Omez" with alcohol
- 8 Contraindications, side effects and overdose
- 9 Analogs
- 10 "Omez" or "Omeprazole" - which is better
Composition and form of release
The modern way of life, or rather, our food - fast food, fatty and spicy foods, snacks, dry food and on the go - is the reason for the massive problems with the gastrointestinal tract. Pharmacists and doctors, saving patients, have developed various drugs that allow you to bring your stomach and intestines back to normal. One of the most popular on this list is Omez. In pharmacies, it can be found in the form of capsules and tablets sold over the counter. As well as lyophilized powder, intended for the preparation of a solution that is administered intravenously. This form can only be prescribed by a doctor, it is used in severe conditions during inpatient treatment.
What is part of Omez?
The main active ingredient is omeprazole. Depending on the form in which the medicine is produced, auxiliary components are used.
In tablets and capsules:
- methyl parahydroxybenzoate (E 218);
- karmoizin (E 122);
- sucrose;
- lactose;
- monohydrate;
- disodium hydrogen phosphate;
- hypromellose;
- gelatin;
- sodium hydroxide;
- talcum powder and others.
In the form of a powder, anhydrous sodium carbonate.
What is Omez assigned to?
This is an effective and often indispensable tool to counter the pathologies of the gastrointestinal tract.
It is prescribed in various situations.
- With gastric ulcer.
- To prevent the return of this pathology.
- With an ulcer of the duodenum in acute form.
- During hypersecretion states: Zollinger-Ellison syndrome, stress-induced ulcers, systemic mastocytosis, polyendocrine adenomatosis.
- When in patients with gastric ulcer bacteria Helicobacter pylori are detected.
- For the prevention of Mendelssohn syndrome.
- For the period of treatment of gastritis.
- If gastroduodenitis is diagnosed.
- With gastropathy, provoked by the prolonged use of non-steroidal anti-inflammatory drugs.
Pharmacological action and pharmacokinetics
The main function of Omez is to block the proton pump. Because of this, it is sometimes called a universal anti-ulcer remedy. The effect of the drug is that it inhibits the enzymes that cause the stomach to produce excessive acid. As a result, acidity decreases.
The effect is temporary. Over a period of 18 to 24 hours, the activity of enzymes and glands returns to normal, because the drug does not interfere with the natural production of gastric juice and softens it only for a short period. So take "Omez" can be long enough.
The peculiarity of omeprazole is that it does not enter the bloodstream, but acts on the body indirectly: under the influence of an acidic environment, metabolites are formed that interact with the glands in the right direction.
Already in 15-20 minutes after taking "Omez" is taken for "work", reaching a maximum in an hour and a half. But one capsule is able to inhibit the production of hydrochloric acid for a whole day, reducing its level by at least half.
As a result:
- pain and heartburn stop;
- spasms in the esophagus disappear;
- increased appetite;
- the patient gets rid of heaviness in the stomach;
- discomfort in the epigastric region disappears.
In the course of treatment, on the fourth day a persistent decrease in gastric secretion appears. This situation persists for another four days after the therapy is over.
The bioavailability coefficient of the main active component "Omez" balances at around 40%. The liver, passing the medicine through itself, deactivates most of the omeprazole.
After an hour and a half, half the volume of the body leaves the liver and kidneys. Full release (through urine and feces) occurs in a day, sometimes the period is extended to 72 hours.
How to take the drug
There is a standard dose for an adult patient - it is 20 milligrams of omeprazole per day. Omez tablets and capsules have exactly this dosage, which greatly facilitates the patient’s life. It is best to take the product in the morning on an empty stomach. This will provide a healing effect for the whole day, until the next dose, and also help digest and assimilate food.
But the treatment regimen varies depending on the diagnosis and condition of the patient. For example, with Zollinger-Ellison syndrome, the daily dose of omeprazole tripled - up to 60 milligrams. Sometimes doctors consider it necessary to prescribe even 120 milligrams per day. And with gastritis, which appeared due to bacteria, the volume of the drug can be twice the standard.
You should always remember: only the doctor prescribes the dosage of the medicine and the length of treatment for them! And only after an accurately established diagnosis.
Omez D gelatin capsules
Capsules come in several subspecies - “Omez”, “Omez D” and “Omez DSR”. Common to all is the prohibition of damage.
They can not:
- break;
- chew;
- disclose;
- retrieve content.
Regardless of the type, the capsules should be swallowed with plenty of water.
Unlike Omez, the other two also contain Domperidone.This component is designed to prevent attacks of hiccups and vomiting, and tone the lower sphincter.
Again, the number of capsules per day depends on the diagnosis. For example, with gastroesophageal reflux and acute gastric ulcer, the doctor will prescribe two capsules to the patient twice a day, from four weeks to two months. For the elimination of pathogenic bacteria Pilori - two pieces twice a day for a week. To prevent re-emergence of wounds in the stomach and duodenum, daily intake of one capsule "Omeza D" will help.
Pills
Since Omez tablets contain the same amount of omeprazole as capsules, the regimen for their use is no different. Let us cite an example of stomach ulcers and duodenal ulcers that are so common today. With such pathologies, the drug is usually used for a month or two, drinking one or two tablets every day. It is recommended to do this on an empty stomach, before breakfast. But judging by the reviews of many patients, this requirement can be completely ignored: before or after a meal - it does not play a role.
When the treatment itself is successfully completed, there is no need to abandon Omez. For the prevention of relapse, one tablet per day will not interfere for some time.
Solution for intravenous administration
Intravenous injection is prepared from lyophilisate powder and injection solvent.
For administration through a dropper (so-called infusion):
- Dissolve 40 milligrams of omeza in 10 milligrams of liquid:
- adjust the volume to 100 milligrams by adding 5 percent glucose or sodium chloride (0.9%);
- inject the solution gradually over a period of 20-30 minutes.
To give an intravenous injection, the first subparagraph is applied accordingly. The introduction of the drug is also slow, within five minutes.
Omez Insta in powder form
Omez Insta powder is used as a suspension. In the morning, an hour before breakfast, the contents of one sachet are bred with two large tablespoons of water and immediately taken. Pour water into a glass with the remainder of the solution and drink everything to the end.
You cannot mix the drug with any other liquids or with food!
If a child is treated in this way, he must be over 12 years old.
Pregnancy and lactation
Many medicines are prohibited or prescribed for pregnant and breastfeeding women with special precautions. As for Omez, experts disagree. Some argue that you should refrain from it. But if it is necessary to treat the patient, and it was not possible to find safe analogues, it is necessary to compare the benefits for the woman’s body and the potential harm for the baby or fetus in the womb. Therefore, if during pregnancy in some cases, such therapy is still allowed, then with lactation it is categorically not.
Others cite several epidemiological studies in which more than 1,000 results were obtained. And they all say that omeprazole does not affect either the health of the mother, or the body of the fetus or baby. So, in therapeutic doses, neither Omez is contraindicated for pregnant or lactating mothers.
Drug interaction
Do not forget to tell your doctor about all the medications you are treating, as the effect of “omeza” may change in combination with them. If it is Omez D, the effectiveness of domperidone in its composition decreases or is generally neutralized by:
- antibiotics;
- antifungal drugs.
Strengthens with the simultaneous use of:
- "Nefazodona";
- HIV protease inhibitors.
Antacids (neutralizing hydrochloric acid in the stomach), sodium bicarbonate, "Cimetidine" reduce the bioavailability of this element.
As for omeprazole, it is a “foe” of “Ketoconazole”, “Diazepam”, “Phenytoin”, “Clarithromycin”, “Warfarin” and some other medications.
Compatibility "Omez" with alcohol
If we keep in mind the purely chemical interaction, neither the composition of Omez nor the composition of alcoholic beverages is incompatible, all of their components are in free contact. But when it comes to the human body, there may be various points that lead to an abnormal reaction to alcohol during therapy. Therefore, it is better not to drink alcohol during the treatment period.
Otherwise, there is a risk of the phenomena accompanying alcohol poisoning:
- repeated vomiting of a fountain;
- "Long-playing" and severe headaches;
- itchy skin rashes;
- prolonged diarrhea;
- depression and severe fatigue.
Contraindications, side effects and overdose
Although, according to statistics, Omez is well absorbed by patients, it does not apply to drugs that have no contraindications and side effects. Therefore, it is extremely important to carefully follow the doctor’s recommendations and forget about self-medication.
It is forbidden to accept:
- with intolerance to any component of this medicine;
- with renal or liver failure;
- children under the age of three.
If the need to be treated with Omez arose in a pregnant or breast-feeding woman, this is done exclusively under the supervision of medical specialists.
Patients should consider the possibility of side effects:
- stomach ache;
- indigestion
- nausea
- insomnia
- puffiness;
- jade;
- changes in taste
- sweating and even bronchospasm.
As for the overdose, so far no one has received any threatening information about this. Even doses greater than 160 milligrams per day do not adversely affect the health of patients.
Analogs
What, with the approval of the doctor, can replace Omez?
- "Ranitidine" - an antihistamine, reduces the production of gastric juice.
- “Soars” - enters the bloodstream, due to which it begins to act much faster. “Japanese”, six times more expensive than “Omez”.
- "De Nol" - unlike "Omez" is antibacterial. It also has an anti-inflammatory effect. The cost is three times higher.
- "Emanera" - the active substance Esomeprazole - a product of omeprazole. "Ambulance" to quickly get rid of stomach pain with gastritis. The price is approximately the same. It is often prescribed in combination with Omez.
- "Omeprazole" - supports optimal acidity of the stomach. Mostly a product of European pharmaceutical companies, which affects the price.
"Omez" or "Omeprazole" - which is better
What should be preferred? What are the differences between them and what are the similarities?
- Omeprazole as an active substance is produced by many pharmaceutical companies in many countries. Including Israeli "Theva", Slovenian "Lek" and others. There is a medicine of the same name.
- Omez is a patented Indian generic based on omeprazole. Its effectiveness has gained recognition in the Russian market.
- The price of Omeprazole German, Israeli or Slovenian production is much higher than Asian.
- Claims that European products are better, cleansed and therefore better treated are nothing more than an echo of the placebo effect.