Fever is a harbinger of many diseases. Getting to the treatment of pathology, it is necessary to bring down the fever and remove pain symptoms that can worsen the patient's condition. Medication "Nurofen" quickly copes with signs of an inflammatory process. What it consists of, when doctors recommend it, and how to take medicine correctly, is useful information in the article.
Material Content:
- 1 Release forms and composition
- 2 Pharmacological action, pharmacodynamics and pharmacokinetics
- 3 In what cases is Nurofen prescribed
- 4 How long does the drug work?
- 5 Instructions for use for children and adults
- 6 During pregnancy and breastfeeding
- 7 Drug interaction
- 8 Contraindications, side effects and overdose
- 9 Analogs
Release forms and composition
The active substance is ibuprofen, which refers to non-steroidal anti-inflammatory drugs. Medicines with it in the composition are presented in a variety of forms. Most common are pills.
There are different types of pills:
- enteric with 200 mg ibuprofen;
- "Nurofen Forte" - 400 mg;
- retard - 300 mg;
- soluble pills;
- powder capsules;
- funds with accelerated action.
For small patients there is a "Children's Nurofen":
- sweet syrup - 100 mg ibuprofen in 5 ml of the drug;
- suppositories for rectal administration - 60 mg in 1 pc.
Gel "Nurofen" is suitable for application directly to the location of pain, in 1 g of the drug - 50 mg of the active ingredient.
In addition to ibuprofen, tablets, suspensions, suppositories and gel have various auxiliary components.
Pharmacological action, pharmacodynamics and pharmacokinetics
“Nurofen" equally has three properties inherent in all NSAIDs:
- anesthetizing;
- antipyretic;
- anti-inflammatory.
Ibuprofen inhibits the production of prostaglandins, which stimulate the development of inflammatory processes, affect the body's thermoregulation. The drug effectively relieves pain of various origins, except spasms in the digestive tract.
The drug is rapidly absorbed from the digestive tract or from the rectum. The effectiveness of the action is observed for 6 to 8 hours after use. Local application allows you to act only on a limited area.
Ibuprofen is excreted by the kidneys and liver unchanged and in the form of metabolites.
In what cases is Nurofen prescribed
Any of the forms of the drug has an effective analgesic and anti-inflammatory effect, and also quickly reduces fever.
Such symptoms are caused by various diseases.
Indications are:
- toothache during teething;
- injuries of various genesis;
- postoperative pain;
- gout;
- acute headache, migraine attacks;
- muscle pain;
- sciatica, bone pain of various dislocations;
- fever of an infectious nature;
- Ear ache;
- algodismenorea (painful periods);
- arthritis of various types;
- unpleasant sensation in the oral cavity, throat;
- bursitis;
- Ankylosing spondylitis;
- oncology pain;
- body reaction to the vaccine in the form of a fever;
- acute pain during delivery.
What helps the drug in gel form:
- muscle spasm;
- arthritis;
- problems with ligaments (sprain, damage);
- aching joint pain;
- sports injuries;
- neuralgia.
The tool quickly stops the focus of pain, because it is applied directly to the site of the lesion. But the drug does not solve the problem, for treatment it is necessary to consult a specialist.
How long does the drug work?
Like all drugs of the NSAID groups, ibuprofen is characterized by a high speed of the action.
The medication is rapidly absorbed into the blood through the mucous membrane of the digestive tract or rectum, as well as through the skin when applying the gel. The speed depends on the form of the drug, as well as on the overall clinical picture and individual characteristics of the patient.
Average time to start:
- children's suppositories - 10 minutes;
- syrup - 15 to 20 minutes;
- tablets, suppositories and gel in an adult dosage - half an hour;
- the drug "Nurofen Express" - 15 minutes.
Instructions for use for children and adults
The medicine serves as an ambulance to quickly eliminate the unpleasant symptoms of a developing disease.
You can not use the drug for a long time to anesthetize or reduce heat.
The maximum duration of admission is 5 days (to normalize the temperature - 3 days), otherwise, instead of treatment, the situation worsens.
Syrup Nurofen
Babies from three months old can be given a suspension if indicated.
In order to accurately measure the required dose, it is convenient to use a measuring syringe enclosed in the package with the medicine. Before you get the right amount of syrup, the bottle should be shaken.
A single dose varies:
- 3 to 12 months - 2.5 ml of syrup;
- 1 to 3 years - 5 ml;
- 4-6 years old - 7.5 ml;
- 7 - 9 - 10 ml;
- 10 - 12 - 15 ml.
It is better for older children to give a remedy in a different form.
You need to drink syrup 3 times a day after eating, not on an empty stomach. You can drink it with another liquid, but there is no urgent need for it, the medicine quickly enters the digestive tract. Between receptions should pass at least 6 hours.
Pills
Pills can be used for adults and children from 6 years. Different types of tablets have a different amount of active substance, so you should start from the dose of ibuprofen.
Standard dosage:
- 6 to 12 years old - 100 mg four times a day;
- from 12 years - 200 mg 3 times throughout the day (maximum 1200 mg per day).
Enteric Nurofen tablets should be swallowed whole, not chewed, washed down with water. Effervescent capsules should first be dissolved in a glass of water.
Candles
Parents often choose this drug for their crumbs. Suppositories are easy to enter the child in the anus, they quickly act.
To achieve the desired effect, you must carefully enter the candle to half the index finger.
Candle dosage for children:
- 3 - 9 months - 1 pc. 3 times a day;
- 10 months - 2 years - 1 candle 4 - 5 times a day.
In case of post-vaccination fever, it is sufficient to apply the suppository once.
Gel Nurofen
Ointment for a site of pain can be used by children, starting from 12 years old, and adults.
Squeeze the gel from the tube (about 5 - 10 cm) and gently rub it into the place where it hurts. It is necessary that the drug is absorbed as much as possible into the skin.
The procedure can be repeated no earlier than 4 hours. Just a day - 4 times.
After applying, be sure to wash your hands so that the medicine does not fall on other areas of the skin or mucous membranes.
The gel cannot be applied to the opening of the wound, as well as to places in the immediate vicinity of the eyes and mouth.
The maximum duration of gel therapy is 14 days. If the symptoms have not improved, you need to consult a doctor and change the method of treatment.
During pregnancy and breastfeeding
The results of the study showed a negative effect of Nurofen on the fetus in the first and third trimester of pregnancy. Therefore, these periods are contraindications for the use of drugs with ibuprofen in the composition.
The use in the 1st trimester threatens pathologies of the development of the unborn child, and the intake in the latter causes complications during delivery and increases the risk of a late miscarriage.
If a woman needs to reduce fever or acute pain during the period from 13 to 27 weeks, the doctor prescribes the drug in a standard adult dosage.
Breastfeeding will have to be temporarily stopped if there is an urgent need for therapy with ibuprofen. After all, the drug in large doses enters the milk, which adversely affects the health of the baby.
Drug interaction
In complex treatment, a medication requires careful study of the composition of other drugs in order to avoid unwanted interactions.
- There is a high probability of poisoning due to the combination of ibuprofen with ethanol, tricyclic antidepressants, barbiturates, phenytoin and rifampicin.
- Other NSAID drugs increase the effectiveness of therapy, but the total dose must be calculated to avoid complications.
- Acetylsalicylic acid is an undesirable component in compatibility, simultaneous administration reduces the effect of drugs.
- Antihypertensive drugs, cardiac glycosides and diuretics weaken the effect when taken with ibuprofen.
- Caffeine in combination with the drug enhances the analgesic effect.
- Ibuprofen enhances the action of anticoagulants.
- The drug, along with corticosteroids and quinolone antibiotics, increases the risk of side effects.
- Serotonin inhibitors and drugs that prevent blood clots can cause bleeding in the digestive organs, if used together with Nurofen.
The interaction of medications in the form of tablets, suspensions and suppositories is described. The gel and ointment, when applied externally, does not act systemically on the body, therefore it does not react with other medicines.
Contraindications, side effects and overdose
It is not worth prescribing a drug for yourself, because there are many conditions in which it is not recommended to take Nurofen. The doctor takes into account possible risks, choosing an effective and safe medication in each case.
In addition to cases of allergy to ibuprofen and additional components, all forms of medication are excluded with:
- pregnancy in the 1st and 3rd trimester;
- breastfeeding;
- under the age of 3 months;
- erosion and ulcers of the digestive tract;
- hyperglycemia;
- bronchial asthma;
- blood diseases (leukopenia, hemophilia);
- ulcerative colitis;
- liver failure;
- internal bleeding;
- hemorrhagic diathesis;
- pathologies of the optic nerve;
- hypertension
- heart failure;
- severe pathologies of the kidneys and liver.
Side effects are observed in some cases. Most often, the drug negatively affects digestion, causing dyspepsia - nausea, vomiting, upsets, epigastric pain.
There are also symptoms of malfunctioning of other body systems:
- allergic reactions in the form of rash, urticaria and edema;
- problems with the central nervous system, manifested by increased excitability, headache, dizziness and insomnia;
- severe lesions of the gastrointestinal mucosa, causing ulcers and bleeding;
- kidney pain, cystitis.
Exceeding the dose threatens more serious complications. In addition to the characteristic signs of intoxication with a medication (vomiting and pain in the stomach), other symptoms appear.
Among them:
- drowsiness, apathy;
- a sharp decrease in blood pressure;
- severe migraine;
- heart rhythm failure;
- rumble in the ears;
- bleeding in the digestive tract.
In acute poisoning, the liver fails, convulsions appear, even a coma occurs.
If the dosage was accidentally exceeded, vomiting should be induced, and sorbents should be taken immediately. If symptoms worsen, call a physician.
Analogs
A number of synonymous drugs is very wide, so if Nurofen is not suitable, you can choose other medicines with ibuprofen.
The following gel medications have a gel texture for convenient external use:
- “Long”;
- Ibuprofen
- "Ibutop";
- "Ibalgin."
List of synonyms in another form:
- "Artrokam";
- Deblock
- Advil;
- Motrin;
- Ibuprofen
- Ibuprom and Ibuprom Max;
- Bonifen
- "Pedea";
- Ibusan
- Ibufen
- "Mig 400";
- Solpafleks;
- Faspik;
- "Brufen SR".
There are plenty of similar drugs in the effectiveness and direction of pharmacology. A list of other NSAID drugs should not be given. The choice in favor of a particular drug is based on the individual situation.