Many drugs are used to relieve spasms and eliminate pain, but the universal remedy Noshpalgin can be distinguished. It helps quite effectively with headaches and cramps. The composition of the medicine contains active substances that act comprehensively on the cause of pain of various origins. Dosage and indications for the use of Noshpalgin is determined by the doctor for each specific case. Due to its quick effect and low cost, the drug has gained popularity among patients.
Material Content:
Release form and composition of the drug
Noshpalgin is a combination drug that anesthetizes, relieves cramps and lowers fever.
Active substances contained in 1 tablet include:
- 500 mg paracetamol;
- 40 mg drotaverine hydrochloride;
- 8 mg codeine phosphate.
In addition to the active substances, additional components have been added to the medicine: magnesium stearate, starch, cellulose and talc.
High efficiency of the drug is provided by its main components:
- Paracetamol. The substance blocks the production of prostaglandins, which provoke a pain syndrome. In addition, it reduces fever and stops the inflammatory process.
- Drotaverinum. Suppresses the formation of enzymes that cause contraction of muscle fibers. This substance relieves spasms and relaxes muscles.
- Codeine. It activates opioid receptors, thereby reducing the excitability of pain centers. In addition, codeine enhances the effects of paracetamol.
The synthesis of these components provides an almost instant analgesic effect.
The drug is produced in the form of yellowish tablets, which have an oblong shape and a dividing risk. The package contains 2 blisters of 6 tablets.
Indications for use
According to the annotation, indications for taking Noshpalgin are such conditions as:
- headache of various origins, including an acute form of tension pain;
- elimination of pain syndrome of any severity;
- spastic pain due to pathologies of the urinary system;
- algodismenorea;
- gastrointestinal tract diseases, accompanied by spasms of smooth muscles;
- brain pathology.
The main purpose of Noshpalgin is the relief of intolerable headaches, migraine attacks and the elimination of spasms of blood vessels.
How to take Noshpalgin: before meals or after
Noshpalgin for headache: for adults, 1-2 tablets at a time are sufficient. If you need to take another pill, this can be done only after 8 hours.
When the course of therapy with this drug is short-term, that is, no more than 3 days, then 6 tablets per day are allowed.
If long-term treatment is planned, the number of tablets is reduced to 4 pieces per day. Moreover, throughout the course of therapy, the state of blood and the level of liver enzymes are monitored.
For fast pain relief, the medicine is taken on an empty stomach.
Children under 12 years of age are prescribed a half tablet once. Then the medicine is given only after 12 hours. The daily dose for children should not be more than 2 tablets.
For elderly patients, dose adjustment is not required if there are no problems with the liver and kidneys. Otherwise, the dose is reduced, and the time interval is 12 hours.
Taking medication during pregnancy and lactation
There is no information on the absolute safety of taking the drug during the period of gestation and lactation, so experts do not recommend taking risks. Codeine, which is included in the composition of the drug, is able to pass through the placenta and excreted in mother's milk. Naturally, this negatively affects the developing fetus and feeding the baby. Accordingly, the conclusion suggests itself - pregnancy and this drug are incompatible.
Combination with other medicines
To avoid unwanted reactions, you need to know about the interaction of Noshpalgin with other medicines.
- Joint administration with chloramphenicol enhances its toxicity, and also increases its half-life.
- Paracetamol absorption is significantly reduced by colestyramine.
- An excessive dose of paracetamol weakens the effects of insulin.
- Combination with urocosuric agents reduces their effectiveness.
- The combination with doxorubicin increases the risk of liver damage.
- Prolonged use of the drug simultaneously with indirect anticoagulant therapy provokes bleeding.
- Noshpalgin enhances the effect of sleeping pills;
- This drug inhibits the absorption of mexiletine;
- Cymedin and histamine receptor blockers disrupt metabolism, therefore, they can enhance the effect of codeine.
By the way, while taking Papaverine in patients, tremor sometimes increases (if it was).
Alcohol compatibility
In the instructions attached to the medicine, such a combination is not said. So, the manufacturer allows the use of alcohol in the treatment of this drug. The medicine does not affect the nervous system, and this confirms the safety of the drug’s interaction with alcohol.
Doctors have a different opinion. All medicines pass through the liver, leaving a certain amount of substances. Alcohol is also processed by the liver, which destroys ethanol and prevents harmful substances from entering the brain. The combination of drugs and alcohol significantly increases the load on this important organ for humans.
The combination of ethanol and the active substance of the drug can increase the number of side effects. A chemical reaction can lead to unpredictable consequences.Immunity is often violated, and malfunctions in the vascular system appear.
Warnings
The patient is required to know about some recommendations that will not allow undesirable phenomena to appear.
- Taking tablets for more than 3 days is allowed only under the strict supervision of a doctor.
- The prescribed dose is strictly forbidden to exceed.
- To quickly stop the pain, it is undesirable to take the medicine during meals.
- With prolonged treatment with this drug, platelet and white blood cell counts should be constantly monitored.
- Medical observation is necessary to rule out codeine addiction.
- If there are problems with the liver or kidneys, the dosage is prescribed individually.
- If the drug is canceled after prolonged treatment, then insomnia or excessive agitation is possible;
- Under the influence of codeine, the effect of alcohol may increase;
- Paracetamol increases its toxic properties in combination with barbiturates and anticonvulsants;
- The simultaneous use of Noshpalgin and psychotropic drugs has a depressing effect on the central nervous system.
The patient must be informed that, if dizziness occurs due to the action of the drug, it is advisable to refrain from driving. It is also better not to work on complex mechanisms that require concentration and increased attention.
Contraindications
To exclude toxic effects on the liver, Noshpalgin injections should not be taken in combination with medicines containing paracetamol.
The product contains codeine, which is dangerous for heart failure, as well as lung diseases. Therefore, it is not prescribed in the presence of these pathologies in the patient.
Absolute contraindications to the use of Noshpalgin:
- recent head injuries;
- excessive pressure inside the skull;
- headache associated with drug intoxication;
- dyspeptic symptoms caused by taking antibiotics;
- taking antidepressants in the next 2 weeks:
- hypersensitivity to any component of the drug;
- alcoholism;
- violation of the hematopoietic system;
- lack of glucose-6-phosphate dehydrogenase enzyme;
- serious pathologies of the kidneys and liver.
The medicine is very carefully prescribed to people of mature age and children under 6 years of age. Patients with arterial hypotension should be aware that drotaverin reduces blood pressure and also dilates blood vessels, so you should not forget about the risk of taking the drug.
Attention! With prolonged therapy with this drug, a blood clotting disorder is noted.
For patients undergoing anticoagulant therapy, this combination medicine is prescribed with extreme caution.
Side effects and overdose
If the drug is taken correctly and without violation of dosage, then adverse reactions occur very rarely.
In clinical trials of the drug, the following complaints were noted:
- respiratory depression;
- allergic skin manifestations: swelling and various rashes;
- jumps in blood pressure;
- deviations in the work of the digestive tract;
- increased heart rate;
- headache and depressing state.
Prolonged use of the drug can cause damage to the liver and kidneys. If the dose is reduced or canceled altogether, the functioning of the kidneys is restored.
When an overdose occurs, intoxication of many organs occurs, but the liver is primarily affected.
Typical signs of overdose:
- sticky sweat appears;
- the skin turns pale;
- pressure drops sharply;
- confusion occurs;
- urge to vomit;
- dizzy begins to manifest general weakness.
In severe cases, convulsions, loss of consciousness, respiratory arrest, and even coma are possible.
Note! The severity of the condition in case of an overdose depends on the level of the exceeded dose, the presence of concomitant pathologies and the speed of seeking medical help.
With a severe overdose, the liver is severely affected.Over 3 days, the symptoms will increase. If you do not take the necessary measures, then the situation will turn into irreversible consequences.
Rinse your stomach immediately. It is advisable to make ventilation of the lungs (forced). The role of antidotes is played by Acetylstein and Naloxone.
Analogs
If necessary, the drug can be replaced with a similar antispasmodic. But it must be borne in mind that each of them has its own characteristics.
The most common analogues can be distinguished:
- Citramon The medicine is famous for its effectiveness and low cost. With an exacerbation of diseases of the internal organs, during pregnancy, as well as children under 14 years of age, the drug is not prescribed. You can take no more than 6 tablets per day.
- Spazmalgon. The drug is based on metamizole sodium. It has an analgesic and antipyretic effect. If there are problems with the liver, kidneys and heart, then the use of the drug is prohibited. Take the medicine, mainly three times a day, 2 tablets at a time. The maximum allowable amount is 6 pieces.
- Spasmonet. Successfully eliminates bile duct problems, as well as colic. Accept also with exacerbation of gastric ulcers. It is often used during childbirth to reduce uterine arousal, to prevent miscarriage or the development of serious consequences.
- Trustin. Differs in universality. It relieves not only pain in the head, but also cramps with cystitis, urethrolithiasis and pathologies of the urogenital tract. It is mainly used as an adjunct therapy in the elimination of pain in the digestive tract. If there is a history of vascular diseases, the drug will have to be abandoned. The dosage is set by the attending physician.
- Drotaverinum. It is usually prescribed for spasm of smooth muscles, quickly removes such complications. Noshpalgin tablets are prohibited for people with low blood pressure and children under 12 years of age. The dose is determined individually.
- UnispazZN. The composition of the drug is completely identical to Noshpalgin. Successfully struggling with spasms in diseases of the intestines and stomach. By the way, it can eliminate toothache.
Before choosing and taking a similar medicine, you must always consult a doctor.
It is impossible to do without drugs of this group. We are talking about analgesics. Almost every person has to resort to them. Often, a doctor is prescribed Noshpalgin. The drug does not have a large list of indications for use, but it acts very effectively and quickly. You can take it at almost any age, but care must be taken. Any medication, including Noshpalgin, has contraindications, ignoring which can lead to serious consequences.
