The tool has an analgesic effect, relieves inflammation and fever. You can find out what Nimesil helps from from the annotation to the medicine. A solution of powder and effervescent tablets can be drunk with acute pain caused by injuries, diseases of bones and teeth.
Material Content:
Forms of release, composition
A medicine is produced in the form of granules. In everyday life, it is customary to call this form of release of Nimesil powder. The mass of the composition in a small bag for a single dose (sachet) is 2 g. The second medicinal form is effervescent tablets Nimesil - round in shape, pale lemon in color with an orange aroma. In one package 10 tablets. They release the drug in Italy, Spain, Germany.
Nimesil is the commercial name of the drug, and nimesulide is its active substance (DV).
The composition of the two forms of release of pain medication contains the same amount of DV - 100 mg. The same auxiliary ingredients are available: crystalline citric acid, orange flavor. Sugar, ketomacrogol 1000, the carbohydrate component of maltodextrin are also added to the powder. The tablets additionally contain sodium and potassium hydrogen carbonates, a sweetener, sorbitol, a chemically inert emulsion of simethicone.
What helps Nimesil
Nimesulide belongs to the pharmacotherapeutic group of non-steroidal anti-inflammatory drugs (NSAIDs). The effect of the drug is due to inhibition of the cyclooxygenase-2 enzyme. The selectivity of the action of nimesulide is to change the functions of only COX-2. It is this feature of the drug that reduces the risk of side effects when taking it.
The drug is prescribed for acute pain caused by:
- cartilage damage, inflammatory reaction and deformation of bone tissue in osteoarthritis / osteoarthritis;
- pathologies of hard tissues of teeth and dental procedures;
- inflammatory process in muscles, bone tissue, joints;
- tendonitis (an inflammatory process in the tendon);
- bruises, sprains and dislocations of the joints;
- lumbago in the lower back (lumbago);
- bursitis (inflammation of the bags of the joints);
- surgical intervention;
- primary dysmenorrhea.
Many of the commonly used NSAIDs are non-selective inhibitors that adversely affect the functioning of cyclooxygenase-1. These properties are possessed by diclofenac, ibuprofen, indomethacin, ketorolac, metamizole, paracetamol.
The safety of Nimesil from pain is an important advantage of the drug. The medicine causes fewer side effects from those organs and systems that patients who use oral NSAIDs usually suffer.
The negative effects of Nimesil may occur when using high doses.
The drug is prescribed as a short course for severe tooth, joint, muscle pain, acute inflammation of the upper respiratory tract. Nimesil is not recommended for a long time to treat chronic inflammation, pain in severe osteoarthritis.
Instructions for use of the drug
The usual dose for adolescents over 12 years of age and adults is 1 sachet or 1 effervescent tablet twice a day. After mixing with water (100 ml), a suspension of light lemon color is obtained for oral administration. The liquid can not be prepared for the future, you need to drink immediately after its preparation. Take nimesil after a meal.
There is no need to adjust the dosage intended for minors and the elderly, patients with moderate renal failure.
The official instructions for use indicate that the duration of therapy should not exceed 15 days. And also drug manufacturers and experts recommend using the minimum effective dose. Caution is necessary to reduce the risk of unwanted symptoms.
During pregnancy and lactation
The drug is strictly contraindicated in the last three months before childbirth, during lactation. Nimesil is not recommended for women who are preparing to conceive a child, as well as in the I and II trimesters of pregnancy. A medicine can adversely affect the fetus, cause pathologies of its organs.
After taking Nimesil, the risk of edema, bleeding in the expectant mother, and miscarriage (in the early stages) increases. The likelihood of a negative effect increases with increasing doses and prolonged use. In the first and second trimesters of pregnancy, Nimesil is used only in case of emergency.
Contraindications and side effects
Nimesulide is not prescribed for diagnosed hypersensitivity to this active substance, allergies to other NSAIDs, to the ingredients in the composition of the powder and effervescent tablets Nimesil.
There are other contraindications:
- bronchial asthma in combination with intolerance to acetylsalicylic acid;
- exacerbation of severe inflammatory lesions of the intestine;
- bleeding disorders;
- acute bleeding;
- stomach ulcers.
Nimesil in any dosage form can not be taken with severe heart and kidney failure, liver dysfunction. The drug is also contraindicated in children under 12 years old, pregnant in the third trimester, breast-feeding women, patients with alcohol and drug addiction.
Potential side effects of nimesulide:
- irritation, itching of the skin;
- hypertension;
- drowsiness;
- dyspepsia;
- flatulence;
- dyspnea;
- constipation;
- swelling
- rash.
Occasionally, the level of liver enzymes rises, jaundice and cholestasis develop. This side effect occurs due to the hepatotoxic effect of the drug.
Analogs of NSAIDs
Preparations with the same active substance in a dosage of 100 mg are produced in Russia.Release forms and trade names of Nimesil analogues: Nemulex soluble powder, Nise, Nimesulide, Nimika, Nimesan, Nimulide tablets.
The cost of Nimesil powder is from 690 to 740 rubles (30 sachets). The price of one bag of granules is 24 rubles. The cheapest Russian analogue is Nimesulide tablets (from 90 rubles for 30 pcs.). Other budget drugs with the same active substance are produced by Russian, Indian, Israeli companies: Nimesan (from 150 rubles), Nimesulide-Teva (from 155 rubles), Nimulide (from 180 rubles), Nemuleks (from 210 rubles), Nise (from 180 rubles).
The group Nimesil analogue is a selective COX-2 inhibitor of meloxicam. Other NSAIDs, non-selective cyclooxygenase blockers (ibuprofen, diclofenac, naproxen, ketoprofen), have analgesic and anti-inflammatory effects. The choice of drug is best entrusted to the doctor. Only a specialist will be able to take into account the peculiarities of the use of each drug for a specific disease or syndrome.
