The therapeutic drug Nimesil is extremely in demand for pain discomfort of various etymologies. However, often this medicine is prescribed to eliminate fever, fever and other manifestations of inflammatory lesions. For productive treatment, you should know how to breed Nimesil and in what quantity to take.

Release form, composition and packaging

This medication relates to non-steroidal anti-inflammatory sulfonamides. Nimesil 100 mg is presented in the form of granules for solution preparation. A cardboard pack contains a number of sachets of 2 g powder each. The main active compound is 100 mg nimesulide. And also the medicine contains a number of additional chemical compounds: ketomacrogol, sucrose, flavoring with orange, maltodextrin.

Indications Nimesil

This remedy is most in demand for pain relief, lowering high body temperature, as well as to eliminate the inflammatory process. Among other things, Nimesil is largely able to eliminate puffiness. The main active compound acts as an inhibitor of cyclooxygenase-2.

This drug is used, as a rule, for the treatment of individual symptoms in such disorders:

  1. Pain discomfort of an acute course.
  2. Post-traumatic pain.
  3. The inflammatory process, which is accompanied by fever.
  4. The postoperative period.
  5. Degenerative disorders of the musculoskeletal system, accompanied by inflammation (radiculitis, arthritis, tendonitis).
  6. Migraines of an acute nature.
  7. Acute pain after dental treatment or other diseases of the oral cavity.
  8. Therapy of urological diseases with inflammation.

Anti-inflammatory effect can suppress or significantly reduce the signs of the inflammatory process. After using the drug, the active compound is quickly absorbed in the digestive tract, and then metabolized in the liver. Excretion is carried out through the renal system. The duration of pharmacological effects is estimated at 8 whole hours. A rapid analgesic effect is noted in the case of paroxysmal pain.

Instructions for taking how to properly breed powder

The standard dosage is up to two pieces per day. Reception is carried out after eating. In order to prepare a suspension for oral administration, Nimesil powder should be diluted in 100 ml of water. Preserving the finished medicine is not recommended. The duration of therapeutic treatment is no more than 15 days. Elderly people often need a dosage adjustment. With renal dysfunction, this medication is taken with caution - with the first undesirable reactions, Nimesil is canceled.

During pregnancy and lactation

Nimesil, like other drugs from the NSAID group, is not recommended for use during pregnancy. This warning is due to the fact that the main component negatively affects the course of pregnancy and the woman’s health (bleeding, closure of the ductus arteriosus, impaired renal function, hypertension are not excluded). Also during therapy, breast-feeding should be stopped, since the main compound is excreted in milk.

Drug interaction

According to the results of clinical trials, Nimesil can be poorly combined with other therapeutic medicines. The described medication should not be taken in parallel with medicines whose action is aimed at reducing blood coagulation, in particular with the drug Furomesid. It is also characteristic of Nimesil to increase the quantitative indicator of lithium in the blood and increase the effect of cyclosporin on the functioning of the kidneys.

With the parallel administration of a medication with methotrexate, the risk of negative reactions increases significantly. Patients with caution are prescribed Nimesil if they are already undergoing therapy with analgesic, diuretic or anti-inflammatory drugs. Also, careful monitoring of patients who combine nimesil and sulfonamides will be required.

Contraindications, side effects and overdose

Before using this medication, you should read the instructions for use. There are a number of cases in which the use of Nimesil is not allowed, since the risk of the progression of undesirable manifestations is significantly increased.

Contraindications include the following cases:

  • patients under 12 years old;
  • diseases affecting the gastrointestinal tract;
  • inflammatory bowel lesions that are in the acute phase;
  • severe pathologies associated with the ability of blood to coagulate;
  • active bleeding in the digestive tract;
  • type 2 diabetes;
  • patients with severe functional impairment of the liver or kidneys;
  • diarrhea, heartburn;
  • intolerance to a specific component of the drug composition;
  • people with high blood pressure;
  • the period of gestation and lactation.
  • severe heart failure;
  • ulcerative colitis.

Adverse reactions can occur in the form of anemia, an allergic reaction, urticaria, nervousness, migraines, and drowsiness. Hypertension, impaired heart rhythm, shortness of breath, and exacerbations of bronchial asthma are extremely rare.More often nausea, vomiting, pain in the stomach. In the case of an overdose, the patient will experience bouts of vomiting, apathy, drowsiness, and bleeding. To eliminate the consequences, individual symptoms are treated, gastric lavage and observation.

Analogs of NSAIDs

In the pharmacy you can find quite a lot of Nimesil analogues that contain the same active compound and act in a similar way. Such synonyms include Nise, Nemulex, Mesulide, Nimesulide, and Prolide. Select a substitute after consulting a specialist.

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