"Neurodiclovit" has anti-inflammatory and analgesic effects, as a means of complex therapy. It is used to eliminate pain with an uninfected focus of inflammation.

The composition of the release form

The drug is available in capsule form for internal use. The dosage form is opaque, has a solid texture. The top cover is beige and the body is yellowish. The capsule itself contains white grains. In one blister is 30 pieces.

The active substance in the agent under discussion is diclofenac.

There are also auxiliary components:

  • titanium dioxide;
  • gelatin;
  • iron oxide red and yellow;
  • povidone;
  • copolymer;
  • talc.

Also, the composition of "Neurodiclovit" includes cyanocobalamin, thiamine and pyridoxine.

Pharmacological properties and pharmacokinetics

Group B vitamins work with NSAIDs.

  • Diclofenac lowers body temperature, eliminates inflammation and is an antiplatelet agent. It reduces the metabolism of arachidonic acids and prostaglandins. Reduces pain in rheumatic diseases and relieves swelling. In the event of injury, it effectively removes swelling in the area of ​​inflammation.
  • Thiamine regulates the amount of fats, carbohydrates and proteins throughout the body. The nerve endings in the synapse are activated thanks to this substance, which is part of the drug.
  • Pyridoxine controls the functioning of the nervous system.Its main role is to synthesize coenzyme for nerve tissue. Participates in the biosynthesis of adrenaline, dopamine and serotonin.
  • Cyanocobalamin regenerates red blood cells and normalizes blood circulation. All biochemical processes depend on it. Thanks to this substance, nucleic acids, carbohydrates and lipids are synthesized. Ensures the normal functioning of all human organs.

Diclofenac is absorbed quickly enough. This process can be slowed down only when taken with food. Complete absorption occurs after 3 hours. It is distributed in plasma and passes into breast milk. Metabolism occurs in the liver, in which about 50% of the active substance is involved. The drug is excreted with the help of kidneys and bile.

B vitamins are diluted with water, which is part of the body. Thiamine and pyridoxine excrete kidneys in an amount of 10%. The rest is absorbed into the intestines. Cyanocobalamin leaves exclusively thanks to bile and only about 7% - through the kidneys.

Why is the drug prescribed?

This medication is prescribed for symptomatic therapy. It relieves pain in the organs in which the inflammatory process occurs.

Indications for its use:

  • recovery after injuries;
  • surgical intervention;
  • dental actions (tooth extraction or gum disease);
  • pain during menstruation;
  • gynecological diseases;
  • otitis media, sinusitis, tonsillitis and pharyngitis.

The drug effectively suppresses foci of inflammation, reduces stress and pain on the entire spine, and relieves discomfort in the joints.

In this regard, it is often prescribed for:

  • chronic polyarthritis;
  • arthritis of any form;
  • spondylarthrosis.

The drug affects the nerve endings, reducing the level of pain, which makes it an effective tool in the following cases:

  • cervical migraine;
  • various pinches;
  • lumbago;
  • sciatica;
  • tendon injury.

Instructions for use of Neurodiclovitis

The drug is used during meals and, preferably, in the morning. The capsule must be completely swallowed without chewing or breaking the case itself, washed down with plenty of water. If you take the medicine half an hour before a meal, then it will work a little faster.

The instructions for use say that the dosage is 1 tablet per day, but can also increase to 3. However, this decision should be made only by the attending physician.

For a quick result, you need to use 1 capsule 3 times a day. After obtaining the desired effect, it is supported by the drug in a dosage of 2 capsules daily. The duration of the course is individual and depends on the form of pain syndromes.

After a few weeks, a stable effective result occurs, which is fixed due to the fact that the body remembers and preserves the effect of the analgesic component for a while.

Use during pregnancy and lactation

Neurodiclovit tablets are categorically contraindicated for use during gestation and lactation.

If there is no other option, and a woman must take this drug during breastfeeding, then the child should first be transferred to artificial nutrition. Even after a short course of treatment with this medication, breastfeeding should be abandoned.

Diclofenac has a bad effect on fertility, so if conception is planned, then it must be postponed for some time. During the course of treatment for diseases causing infertility, this drug will only reduce the likelihood of conception.

Can I drink alcohol while taking the drug

Neurodiclovit inhibits the central nervous system, and in the presence of alcohol, this effect is enhanced. Thus, drinking alcohol during treatment is not recommended. The drug can increase the penetration of alcohol into brain cells, which can cause damage to the structure of neurons.As a result, the activities of the department responsible for thinking are disrupted.

Drug Interactions with Other Drugs

Diclofenac, which is present in the composition of the product, can increase the level of digoxin and cyclosporine, so the dosage of these substances must be reduced.

Besides:

  • The drug weakens the action of diuretics, increasing the concentration of potassium in human blood.
  • It is forbidden to take "Neurodiclovit" in combination with anticoagulants, thrombolytics, ethanol and St. John's wort, as this can trigger gastrointestinal bleeding and increase the risk of ulceration.
  • NSAIDs increase the likelihood of side effects. The toxicity of cyclosporine increases.
  • Paracetamol adversely affects the function of Neurodiclovitis, stimulating the release of harmful components. The kidneys may not be able to withstand the load, resulting in urgent hospitalization.
  • Aspirin lowers the amount of diclofenac in plasma.
  • The risk of developing blood clots greatly increases if you combine the reception with tablets of the valproic acid group.
  • Photosensitivity is provoked by substances in the composition of Neurodiclovit. Ethanol and anticonvulsants prevent the penetration of vitamins B into the body.

Contraindications, side effects and overdose

The medication is contraindicated in the presence of the following ailments:

  • individual intolerance or allergy to certain substances;
  • gastritis and gastrointestinal ulcer;
  • bleeding in the intestines and stomach, previously diagnosed;
  • intracranial pressure;
  • asthma, lung problems;
  • poor blood coagulation;
  • disorders in the liver and kidneys;
  • cardiovascular problems;
  • increase in blood potassium content;
  • pregnancy and lactation.

The drug is also prohibited for children under 18 years of age.

In addition to the above aspects, there are special instructions. These include diseases that allow the use of "Neurodiclovit" only under the strict supervision of the attending physician. In this case, you must carefully monitor the dosage. When unpleasant symptoms appear, a single dose of the drug should be immediately reduced. In such situations, it is important to constantly listen to your own body.

The list of such diseases includes:

  • anemia;
  • arterial insufficiency;
  • Ischemic heart disease;
  • diabetes;
  • high blood cholesterol;
  • peripheral ailments;
  • helicobacteriosis;
  • inflammatory foci of the intestine;
  • porphyria;
  • diseases of the skin.

Among the circumstances that require constant monitoring by a doctor when taking the drug are also included: a long course of taking drugs acting on the central nervous system, severe dehydration (diarrhea and vomiting), the recovery period after a serious operation, bad habits, age after 60 years.

Side effects caused by the medication can be classified depending on the area of ​​exposure.

Digestive organs:

  • pain and discomfort in the abdomen;
  • diarrhea;
  • nausea leading to vomiting;
  • ulcer and bleeding in the stomach;
  • jaundice;
  • stomatitis;
  • dry mucous membranes;
  • hepatitis;
  • cirrhosis, pancreatitis and colitis;
  • increase or decrease in appetite.

Nervous system:

  • headache;
  • fainting
  • dizziness;
  • sleeping condition;
  • depression;
  • cramps
  • anxiety.

Sensory organs:

  • visual and hearing impairment;
  • violation of the sensitivity of receptors, most often taste;
  • scotoma.

Skin:

  • itching, rash;
  • zzzema of various nature, dermatitis;
  • hives;
  • rarely - baldness.

Genitourinary system:

  • swelling, as a result of moisture retention in the body;
  • nephrotic symptoms;
  • increase in protein;
  • hematuria;
  • acute renal failure;
  • increased nitrogen in plasma;
  • decreased sex drive.

Respiratory organs and cardiovascular system:

  • pneumonia;
  • cough and swelling of the pharynx;
  • increase in pressure;
  • heart attack and stroke;
  • pain in the ribs.

Allergic manifestations:

  • vasculitis;
  • swelling of the face;
  • anaphylactic shock.

In the composition of the blood, a decrease in hemoglobin, leukocytes, platelets can be detected. The manifestation of chronic diseases in acute form is possible.

As a result of the wrong course of treatment, the symptoms described below may occur. In this case, you should immediately call an ambulance.

  • Severe shortness of breath and dizziness.
  • Shortness of breath, sensation of constriction in the lungs.
  • Loss of consciousness and coma.
  • Leg cramps.

If the excess of the permissible dose has already occurred, and similar reactions take place, first of all, it is necessary to empty the stomach by taking sorbents, for example, in the form of activated carbon (1 tablet per 10 kg) and drinking plenty of fluids. As an additional remedy, diuretic drugs are used. A person should be constantly monitored, since in such cases the central nervous system is inhibited and the respiratory process is disturbed.

Analogs of Neurodiclovitis

There are a lot of analogues of this drug, but they have a completely different active substance. The combination of diclofenac with B vitamins is unique to the original. Known analogues of "Neurodiclovitis" containing only one enzyme, diclofenac.

List of the most famous medications:

  • "Artrotek" in the form of tablets;
  • Voltaren is available in the form of suppositories and injections;
  • "Iklovit";
  • "Naklofen";
  • "Flotac" in the form of capsules.

The therapeutic effect of analogues is identical, but the result may vary.

After a thorough study of the instructions of the drug, it becomes clear that it is a fairly strong analgesic. When used correctly, the effect is observed very quickly, and the action extends to all vital systems of the human body.

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