Antihistamines of the last generations act during the day, rarely cause side effects. Various Loratadine analogues are prescribed for allergies. The drugs will also help to cope with the reaction of the body to toxins of pathogens of infectious and parasitic diseases.
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Composition (active substance) of loratadine
The trade name of the antiallergic drug is the same as the international non-proprietary name (INN). The content of loratadine in the tablet is 10 mg. Auxiliary ingredients are represented by the components traditional for solid dosage forms: lactose, corn starch, magnesium stearate.
Loratadine is a representative of the second generation of antihistamines. The active substance (DV) is a blocker of histamine H1 receptors. The development of an allergic reaction slows down or stops due to a decrease in the release of an inflammatory mediator into the blood. Loratadine lasts longer, causes less side effects compared to the first generation of antiallergic drugs.
Instructions for use of the drug
Loratadine is taken without regard to meals. Children from 3 to 12 years old are given once ½ tablets. The dose for a child of this age group with a weight of less than 30 kg should not exceed 5 mg / day. Adults and adolescents over 12 years old with a body weight of more than 30 kg are prescribed 10 mg / day (1 tablet).
And also the instructions for use say that patients with chronic renal failure, the elderly do not need to adjust the dosage.If liver function is impaired, then you should drink 1 tablet every other day.
The effect of the drug begins 30-40 minutes after ingestion. The maximum effect should be expected 10 hours after administration.
An antihistamine is prescribed in a short course to eliminate the allergic component that accompanies colds in children. With a runny nose, sneezing, itching of the nasal mucosa, lacrimation, give the child a preschool and primary school age half a tablet at night. Loratadine has virtually no sedative effect, but adults are also better off taking pills before bedtime.
Russian analogues in tablets
Loratadine and substitutes are prescribed to get rid of the manifestations of allergies. Antihistamines eliminate the itching that accompanies contact dermatitis, eczema, and urticaria. The drugs help to cope with the symptoms of perennial allergic rhinitis, conjunctivitis, and hay fever.
Prescribe loratadine and analogues of the drug for allergies to insect bites, with the development of angioedema (Quincke). This is a sudden strong swelling of the skin, mucous membrane, subcutaneous tissue in a limited area of the body (eyelids, lips, ears, hands).
Loratadine tablets are a generic of the original medicine Claritin.
A foreign drug can be purchased at a pharmacy at a price of over 200 rubles (10 tablets). Loratadine is produced in Russia. The cost of the drug is in the range of 10-50 rubles (10 pcs.). This is the cheapest substitute for antihistamines manufactured abroad.
The effectiveness and safety of the drug depend mainly on the concentration and purity of the active ingredient, the composition of the auxiliary components. Many conscientious experts consider the differences in properties between generics and the original tool to be insignificant. However, the former are several times cheaper than the latter, which is important for patients.
Trade names of other structural analogues of domestic production:
- Loratadin-Akrikhin;
- Vero-loratadine;
- Clarotadine;
- Clarisens.
In Russia, an order of the Ministry of Health is in force, requiring doctors to indicate in the prescription not the trade name of the drug, but its INN (active substance).
Almost all antihistamines of 2-3 generations have a similar mechanism of action. Budget tablets made in Russia contain DV cetirizine. The tool begins to act 20-60 minutes after administration.
Desloratadine is a powerful anti-allergic effect. The tablets are manufactured under this INN by the Russian companies Vertex and Canon. Desloratadine begins to act half an hour after administration. A big plus is also the lowest risk of drowsiness among antihistamines.
Domestic syrup substitutes
Small children are preferable to give liquid medicine. Analogs for the active substance are Loratadin-Akrikhin, Clarisens, Clarotadin syrups. The production of liquid dosage forms is a little more expensive. The cost of Loratadin substitutes in the form of syrup, produced in Russia, is on average 95 rubles.
Foreign generics in tablets and syrup
Structural analogues contain the same AI in the same dosage. Such drugs released abroad are Loratadin-Teva, Lorahexal, Lomilan tablets, Claritin tablets and syrup, Erolin.
Lorahexal is one of the cheapest foreign analogues of Loratadin (the price of a package of 10 tablets is 55 rubles).
Ebastin belongs to the second generation of antihistamines. The trade name is Kestin. The drug is characterized by the rapid development of the antiallergic effect (within 40-60 minutes), its long-term preservation (48 hours).
Trade names of imported antihistamines of the latest generations in tablets (DV):
- Desloratadine, Erius, Desal, Lordestine, tablets for resorption Blogir-3 (desloratadine).
- Levocetirizine, Zodak Express, Suprastinex, Xizal (levocetirizine is an improved cetirizine).
- Fexofenadine, Telfast, Fexadin (fexofenadine).
- Parlazin, Zyrtec, Cetrin, Zodak (cetirizine).
Drops of Fenistil are prescribed to babies older than 1 month. Side effects of dimethindene in the composition are poorly expressed, compared with other first generation antihistamines.
Zyrtec in drops is prescribed for allergies to children from 6 months. The tool acts gently, soothes itching, helps with severe cold, sneezing, urticaria. Zodak drops and Parlazin are suitable for the treatment of babies older than 12 months.
DV syrups Erius, Eslotin, Blogir-3 - desloratadine. An analog is Desal in the form of a solution for oral administration. Drugs are prescribed for the treatment of urticaria, allergic rhinitis, hay fever, pruritus and rash.
Liquid antihistamines can be taken by patients of any age. You must use the table in the instructions to accurately determine the dose. It depends not only on age, but also on body weight.
Loratadine is not the most powerful antihistamine, but one of the most studied and safe. With allergic rhinitis, hay fever, allergic dermatosis, doctors prescribe analogues with a more powerful effect.
