"Clenbuterol" is a drug that eliminates spasms in the bronchi, which reduces coughing attacks and facilitates the removal of sputum. Its use for the prevention and treatment of children is allowed.

Forms of release and composition of the drug

A medicine is produced in the form of a syrup - a colorless liquid with a pleasant raspberry odor.

The main active ingredient is Clenbuterol hydrochloride.

  • In each tablet, this element is contained in an amount of 0.02 mg.
  • 5 mg of syrup accounts for 0.01 mg of the substance.
  • For children's syrup, the dose is reduced to 0.005 mg per the same 5 ml.

Additional components include glycerol, sorbitol, citric acid monohydrate, propylene glycol, raspberry essence, ethanol, water and other elements.

The 100 ml bottle is made of dark glass. One copy of a glass container and a measuring spoon are placed in cardboard packaging.

Also, the product is made in the form of tablets placed in blisters.

Pharmacological action, pharmacodynamics and pharmacokinetics

The active component of the drug is selective beta2-adrenergic agonist. Therefore, the action of this substance is based on the stimulation of this type of receptor, located mainly in the bronchi.

As a result of the effect on the receptors, the chain of reactions of adenylate cyclase - CAMP - protkininase A is activated. Then the action of the drug reaches myosin, which is a component of smooth muscle fibers and, when interacting with actin, relaxes the bronchi. Due to this, the narrowing of the lumen of the respiratory tract (for example, with an attack of asthma) and the relief of breathing in general.

Clenbuterol also has a secretolytic effect. The tool is able to slow down the release of inflammatory mediators and other compounds that increase bronchospasm from basophil cells.

As a result of this, edema decreases, stagnation in the bronchi is eliminated, and the protective mechanisms of the airway mucosa are improved. All these actions are reduced to the expansion of the bronchi and improvement of expectoration of sputum.

The drug is used internally, after which it is absorbed quickly and almost 100% into the digestive tract.

  • The action of the active substance begins after 10 - 15 minutes.
  • The maximum therapeutic effect appears 2 to 3 hours after administration.
  • The half-life of the substance is 3.5 hours.
  • Binding to blood plasma proteins varies from 89% to 98%.

The metabolism of the drug is carried out by the liver, and about 78% of the metabolites are excreted in the urine. Some of these substances are excreted in the intestines with bile.

Which cough should Clenbuterol take, with dry or wet

This tool is effective in the treatment of both wet cough and dry. The drug eliminates inflammation, increases mucus production by the cells of the respiratory tubes, and also prevents the growth of pathogenic bacteria.

Especially productive is an adrenomimetic agent for removing large amounts of sputum from the bronchial system. In addition, the substance has a softening effect.

"Clenbuterol" is successfully prescribed for the treatment of pathologies such as chronic obstructive bronchitis, bronchial asthma and emphysema, as well as other diseases of the respiratory apparatus with bronchial obstruction syndrome.

Instructions for use and dosage for children and adults

Despite the relative safety of the drug under discussion, before taking it, you should definitely subtract the instructions attached to it.

Clenbuterol Pills

The form of the medicine in the form of tablets (Clenbuterol Sofarma) is used internally. A specific dose of the drug is prescribed based on the weight of the patient and the presence of adverse reactions to the administration of the drug.

On average, the dosage for adult males is approximately 100 to 140 micrograms, for women 80 to 100 micrograms per day.

At the same time, Clenbuterol 0.02 mg tablets are taken with a lower dose, eventually increasing it to the recommended one.

Adults are often prescribed one tablet twice a day, and to maintain a positive effect, the medicine is used half a tablet in the morning and evening. With especially severe pathologies, they first drink 2 tablets in the morning and in the afternoon, and after the appearance of positive dynamics, the dosage is reduced.

Clenbuterol for children 6 to 12 years old is used half a tablet twice a day. From the age of 12, a half-tablet is prescribed 2-3 times a day or a whole twice a day.

Cough Syrup for Children

Clenbuterol syrup 0.001 mg / 1 ml for children should be used in compliance with the scheme specified in the instructions for the medicine:

  • children under 8 months with a weight of 4 - 8 kilograms - 2.5 ml of syrup twice a day;
  • from 8 months to 2 years (weight, approximately, 8 - 12 kg) - 5 ml twice a day;
  • in children from 2 to 4 years old (weighing about 12 - 16 kilograms) - 7.5 ml 2 times a day;
  • children 4 to 6 years old and weighing from 16 to 22 kg - 10 ml twice a day;
  • from 6 to 12 years (from 22 to 35 kilograms) - 15 ml twice a day;
  • for children over 12 years old and weighing more than 35 kg - 15 ml 2-3 times a day.

Clenbuterol in the form of syrup can also be used in adult patients at a dose of 15 ml, two to three times a day at the beginning of therapy (the first few days). Further, when the condition improves, the volume of the drug is reduced to the required amount - 10 ml twice a day. Treatment takes 2 to 3 days to eliminate the acute manifestations of the disease.

Taking the medicine in order to maintain the effect cannot be continued for more than 7 days. An increase in the duration of Clenbuterol administration is carried out only by a doctor.

During pregnancy and lactation

The drug "Clenbuterol" is not used in the first and third trimester of pregnancy. This is due to his ability to inhibit labor. Also, it is not recommended to use the medication in the second trimester, only in rare cases, allowing the use of the drug in the form of inhalation.

When conducting studies of the drug, it is not reliably established whether it can be excreted in breast milk. Therefore, the agent should be prescribed during breastfeeding only in situations where the expected positive effect for the woman exceeds the possible harm to the fetus.

Drug interaction

Before using Clenbuterol, you need to know about its interaction with other medicines.

  • When combined with beta-andrenoblockers, the bronchodilator effect of the drug decreases or disappears.
  • In combination with cardiac glycosides, monoamine oxidase inhibitors and theophylline, it can disrupt the conduction of impulses in the heart, which leads to changes in heart rate.
  • The drug reduces the effect of antihypertensive drugs.
  • Clenbuterol worsens the effect of hypoglycemic drugs, therefore, when used together, dosage adjustment is required.
  • The effect of the drug is enhanced by tricyclic antidepressants, other beta-andrenomimetics and anticholinergics.
  • In combination with sympathomimetics, the toxicity of the drug increases.
  • Halogenated compounds for anesthesia may increase the ability of the drug to cause arrhythmia.

If it is not possible to stop taking these medications, the doctor replaces Clenbuterol with an analog drug that has a similar effect in the treatment of a particular disease.

Clenbuterol Compatibility with Alcohol

Alcohol intake together with this agent can provoke the development of adverse reactions indicated in the annotation. In this regard, it is recommended to abandon the use of alcoholic beverages for the period of treatment with Clenbuterol.

Contraindications, side effects and overdose

Contraindications to taking the medication:

  • hypersensitivity to the components of the drug;
  • intolerance to the substances that make up Clenbuterol;
  • heart rhythm disturbance (tachycardia, arrhythmias);
  • thyrotoxicosis;
  • aortic stenosis;
  • severe form of coronary heart disease (myocardial infarction).

Treatment with the drug should be carried out with extreme caution with:

  • diabetes mellitus;
  • hyperthyroidism;
  • pathologies of the circulatory system.

In such situations, therapy is carried out in a hospital under the supervision of doctors and under the supervision of tests.

Side effects:

  • From the side of the central nervous system: dizziness, prolonged headaches, the appearance of anxiety, sleep disturbance, tremor of fingers on the hands.
  • Circulatory system: tachycardia (increased pulse), high blood pressure, extrasystole, heart pain.
  • With regard to the digestive tract, the appearance of dry mouth, pain in the abdomen, a feeling of nausea and vomiting are possible.
  • Local and general manifestations of allergies: urticaria, rash on the skin, bronchospasm, angioedema.
  • Other complications: muscle cramps, severe redness of the face, increased sweating, hypokalemia, and muscle aches caused by it.

There is a risk of withdrawal and resistance syndrome when you stop taking the medicine.

In case of an overdose, the intensity of side effects increases: arrhythmias, tachycardia, high blood pressure, pain in the heart, trembling limbs. There is a risk of hypokalemia, which makes it necessary to regularly monitor the concentration of potassium in the blood.

In such cases, the drug is immediately stopped. When symptoms of an overdose appear, urgent gastric lavage is necessary. For this, activated carbon is used, intravenous administration of infusion solutions for detoxification and symptomatic therapy are carried out.

Also, exceeding the required amount of medication can worsen the course of bronchial asthma. In such situations, you must immediately consult a doctor.

Analogs

Clenbuterol's analogues in terms of the effect are such drugs as Stanozolol, Saltos, Azmaril, Sedoril ASG and others.

Only a doctor can replace a medical product with its analogue, taking into account the indications and contraindications for its use.

Thus, "Clenbuterol" is an effective drug for the treatment of diseases accompanied by bronchospasm and difficult discharge of sputum. However, before using it, it is necessary to study the contraindications to the use of the drug in order to avoid the development of life-threatening conditions.

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