Anyone can experience digestive upset. This can be facilitated by simple overeating, as well as gastrointestinal diseases. "Pancreatin" is a medicine that contains enzymes of the pancreas of natural origin, and they can both help the functioning of the body, and completely take on all the work. From this article, we will learn how to take Pancreatin for patients of different ages.
Material Content:
Composition (active substance) "Pancreatin"
The rounded shape of the pill is green on the outside, covered with a soluble membrane in the intestine. Inside the tablet has a white, or with a slight yellowish tint composition. And they also produce “Pancreatin” of another kind - a dragee in a brown shell, with a break they are white with a brownish tint. An odor may not come from pills.
The enzyme contains three main substances.
These are pancreatic enzymes:
- lipase;
- amylase;
- protease.
There are still compounds that do not have a therapeutic effect, but are designed to create a medicinal mass. Pancreatin tablets are available in 125 mg, 250 mg doses (may be designated as 25 units).
pharmachologic effect
The pancreatic enzymes that make up the drug are obtained from the body of cattle, cattle, and pigs.
When these substances enter the stomach, they compensate for the insufficient activity of the production of unique enzymes by the pancreas, which improves digestion.
Fats, proteins and carbohydrates break down faster (into amino acids, monosaccharides, fatty acids and dextrins), are fully absorbed into the intestinal wall.
The pill coating prevents the agent from acting in the stomach. The drug begins to disintegrate only in the duodenum. Thanks to the action of substances, the digestive process improves, the state of the digestive tract normalizes.
Why is the drug prescribed?
The drug acts on many ailments associated with the gastrointestinal tract, and it is prescribed not only as the main treatment, but also to help in general therapy.
Pancreatin helps people with the following diseases digest food:
- inflammation of the gastrointestinal tract;
- acute and / or chronic diseases of the gallbladder, biliary tract, liver;
- pancreatitis after transplantation;
- disturbances in the functioning of the digestive tract systems associated with the immobility of the patient, or with problems in chewing;
- digestive disorders when consuming heavy foods or unusual foods, overeating, intoxication (food poisoning);
- fibrosis of the cystic origin of the pancreas;
- chronic insufficiency of the digestive tract.
In addition, "Pancreatin" is recommended to be taken to prepare the peritoneal organs for ultrasound and radiography.
Instructions for use for children and adults
The dosage should be selected in accordance with the severity of the disease, age and weight of the patient. Basically, a doctor prescribes up to 4 pills for each meal.
The number of tablets in the complete absence of pancreatic functioning can reach up to 50 pcs. per day, which fully compensates for the daily rate of lipase.
For children, the calculation is as follows: 2-4 years - 7 kg tablet, more than 4 years - 14 kg tablet.
The average application instruction is as follows:
- from 3 to 5 years - a tablet with each feeding;
- 6-7 years - up to two pills at a time;
- 8-9 years - 2 tablets;
- from 10 to 14 years - from 2 to 4 pills with each meal;
- "Pancreatin" for adults - 4 pcs. for single use.
You need to take medicine before or after meals, be sure to drink plenty of water.
Children should take the drug only under the supervision of their elders!
The instructions given are not specific to each patient. The dosage of the drug and the number of doses should be prescribed by a specialist.
Use during pregnancy and lactation
From the very beginning of pregnancy, women begin to feel discomfort in the digestive tract: heaviness, heartburn, nausea and vomiting, problems with stool. All these troubles are associated with the active work of progesterone, which to preserve the fetus relaxes not only the walls of the uterus, but also the intestines. The best way to get rid of problems is to adjust the diet: mode, consumed foods.
Pancreatin, like other drugs on enzymes, is not harmless to pregnant women and their unborn children.
Such drugs can not cope with the ailments described above, since they have a completely different nature of origin, not associated with the production of enzymes.
Pregnant women can take Pancreatin only with the prescription of a doctor for diseases indicated for the consumption of enzymes. The annotation to the drug states that taking the drug is not recommended for pregnant women, but it can still be prescribed by specialists if there will be more benefit than possible harm.
As for the period of lactation, then doctors advise to abandon breastfeeding for the duration of therapy, and switch temporarily to the mixture. “Pancreatin” is prescribed to lactating women only in extreme cases, because a baby will not replace a single mixture of mother's milk, and in the future it will be very difficult to wean a bottle.
Dosage is selected only on the basis of individual patient indicators. You can not increase or decrease the amount of the drug yourself.
Interaction with other drugs
If the patient is taking Pancreatinum, other medications must be prescribed carefully, since many substances, when reacting, can harm or reduce the effectiveness of therapy.
Joint administration is not recommended in such cases:
- Enzyme preparations are not applicable in the treatment of anemia, as they reduce the absorption of iron-containing drugs. You need to drink them separately from each other.
- Antacids, which contain magnesium hydroxide or calcium carbonate, reduce the effectiveness of enzyme drugs.
- "Pancreatin" partially blocks the absorption of folic acid, so the dosage of the latter should be increased (only by a doctor).
- Reducing the concentration of sugar in the blood are less effective when taking "Pancreatin" or its analogues.
The use of any, even the most harmless drugs, for example, funds with iron, together with the specified drug, should be agreed with the doctor.
Contraindications, side effects, overdose
If you just overeaten, and you are offered a pill of enzymatic origin, do not rush to take it. The fact is that Pancreatin, like all similar medicines, has some contraindications.
You can not drink the drug in conditions:
- pancreatitis in acute or chronic form;
- increased bilirubin;
- liver failure;
- hepatitis and obstructive jaundice;
- bowel obstruction;
- intolerance to the components of the medical composition;
- cholelithiasis.
With extreme caution, Pancreatin is used at the age of up to three years. And also under the supervision of a doctor, treatment with enzyme preparations should be carried out if the patient has anemia. In cases of prolonged use of "Pancreatin" and people with minimal iron deficiency in the body, iron-containing agents are prescribed.
Enzyme preparations are not recommended even with such rare ailments:
- galactose and glucose malabsorption syndrome;
- lack of lactase;
- galactose intolerance.
Side effects from enzyme treatment are extremely rare, and are observed in only 1% of patients.
In 90% of situations, they appear due to non-compliance with the doctor's prescriptions (exceeding the dosage or the number of applications per day), concomitant use of drugs incompatible with Pancreatin, self-medication, and unnecessary use.
Taking the medication described may result in the following ailments:
- change in stool, bowel obstruction;
- discomfort in the stomach;
- nausea, less often - vomiting;
- allergies
- an increase in the concentration of uric acid in the blood;
- skin irritations.
If the dose is exceeded, an overdose appears, which is expressed by symptoms:
- vomiting
- diarrhea, but more often constipation;
- abdominal pain.
If there are unpleasant symptoms when taking "Pancreatinum", you need to cancel the therapy before consulting a doctor.
Analogs
Today, many pharmacological companies produce enzyme products. Only "Pancreatin" can be found under a dozen brands, analogues and can not be counted.
The most popular and affordable drugs, the composition of which completely or almost completely duplicates the drug in question, are the following:
- Mezim;
- "Creazim";
- Pancreasim
- Pongrol
- "Creon";
- Panzinorm.
This is not a complete list of drugs that can be purchased in return for Pancreatin.
Although enzyme preparations are dispensed without prescriptions, do not rush to purchase them without a prescription. The medicine will not help with diseases that are not related to the gastrointestinal tract, but with similar symptoms, and it is unjustifiable to take enzymes.