Fever and acute pain require immediate intervention and effective medications. To quickly remove unpleasant symptoms, often used strong medications, which include "Nimesil." What the drug consists of, when and to whom it is prescribed, how to take Nimesil in order to avoid complications - the answers to questions in our article.

Powder composition

Yellow granules of the drug are intended for the preparation of a suspension.

The active substance is nimesulide, a non-steroidal anti-inflammatory agent with a wide spectrum of action. A single bag with 2 grams of powder contains 100 mg of active substance.

The auxiliary components are:

  • sucrose;
  • lemon acid;
  • maltodextrin;
  • orange flavoring;
  • macrogol.

Pharmacological action and indications for use

The drug acts directly on prostaglandins, reducing their ratio in the body. Since these substances act as mediators of inflammation and pain, a decrease in their number suppresses these symptoms and improves well-being.

Nimesulide acts regardless of the nature and cause of the pain, the anesthetic effect lasts up to 6 - 7 hours. In addition, the drug inhibits inflammatory processes, normalizes body temperature and relieves swelling.

The action of the drug is aimed at eliminating the symptoms, and not at the cause of the disease.

Indications for use are:

  • various injuries;
  • pain in the spine, lower back;
  • migraine;
  • postoperative syndrome;
  • joint pain;
  • painful periods;
  • radiculopathy of various origins, sciatica;
  • tendonitis;
  • arthritis, rheumatism.

Often used the quick effect of "Nimesil" for toothache, when you need to eliminate pain in the shortest possible time. The need for taking the drug also arises after dental procedures.

How to take Nimesil

The drug irritates the mucous membrane of the digestive system, so you need to take it after a meal. Immediately before use, a suspension should be prepared from the powder, which is not intended for long-term storage.

How to breed Nimesil powder

  1. Open the sachet with granules, pour into a cup or glass.
  2. Add a hundred milliliters of clean warm water to the dishes. It is necessary to breed "Nimesil" with water about 36 degrees.
  3. Shake until a homogeneous consistency is formed.

The suspension is ready to use.

Dosage regimen

Children under 12 years of age are prohibited from taking nimesulide due to the high toxicity of the drug.

The maximum dosage for adult patients is 100 mg (1 sachet) twice a day.

If the analgesic effect lasts longer, you can reduce the amount of medication, but in no case increase it.

Symptomatic treatment can last no more than 14 days. If the drug does not help, you should consult a doctor for advice.

During pregnancy and lactation

High toxicity and the ability to penetrate the placental barrier puts the drug on the list of prohibited medicines for women while waiting for a child.

If during the first two trimesters of pregnancy in some cases, doctors prescribe a short-term course of nimesulide to eliminate painful symptoms, then in the third trimester this is ruled out.

After all, the medicine causes certain risks for the expectant mother and child:

  • decreased kidney function;
  • changes in blood pressure;
  • water shortage;
  • premature closure of the ductus arteriosus;
  • decreased uterine contractility;
  • increased swelling;
  • bleeding
  • deviations in the development of the child.

Taking a nimesulide through breast milk will only harm the baby. Therefore, nursing mothers need to abandon this method of eliminating pain and choose a different drug.

Drug interaction

You can not combine nimesulide with such drugs:

  • diuretics, antiarrhythmic and antihypertensive drugs - their effectiveness decreases;
  • other NSAIDs, lithium-containing drugs - side effects are exacerbated;
  • anticoagulants and corticosteroids - the risk of internal bleeding and mucosal irritation is increased;
  • ACE inhibitors and cyclosporine - the toxic effect on the kidneys and liver is exacerbated;
  • Furosemide - causes an accumulation of sodium and potassium, metabolism is difficult.

Read also:ACE inhibitors - list of drugs

Contraindications, side effects and overdose

The high effectiveness of the drug under discussion indicates its increased toxicity.

Therefore, in the instructions for use, in addition to the standard hypersensitivity to the components of the medication, an impressive list of contraindications is indicated.

Namely:

  • age up to 12 years;
  • pregnancy;
  • lactation;
  • fever in acute respiratory diseases;
  • renal failure;
  • gastric ulcer in the acute stage;
  • severe liver pathology;
  • internal bleeding;
  • stable arterial hypertension;
  • chronic alcoholism;
  • heart defects;
  • diabetes;
  • the period after coronary artery bypass surgery;
  • clotting pathology;
  • hyperkalemia

In addition, along with an effective effect on the source of pain, the drug causes unwanted symptoms, disrupting the activity of other systems.

Possible reactions:

  • dyspepsia symptoms - pain in the stomach, urge to vomit, bloating, upsets;
  • general weakness, fatigue, anemia, dizziness;
  • pressure surges, hypertension;
  • edema, itching, urticaria, peeling of the skin;
  • hyperhidrosis;
  • hematuria, problems with urination;
  • renal and hepatic insufficiency;
  • bleeding in the digestive tract, ulcer;
  • muscle spasms;
  • blurred vision;
  • panic state, rapid excitability, insomnia;
  • breathing problems, bronchospasm;
  • lowering body temperature.

An overdose threatens with unpleasant symptoms from the digestive system (nausea, pain and even bleeding), general weakness and apathy, as well as a sharp increase in blood pressure. With a significantly increased dose, a person can fall into a coma.

Cheap analogues of Nimesil

The cost of the described medication is quite affordable for consumers. In addition, in addition to this drug, there are other drugs with nimesulide.

Among them:

  • "Flolid" in suspension, tablets or granules;
  • "Aponil" in tablets;
  • "Nise" in pills;
  • "Actasulide" in tablet form;
  • "Nemulex" in granules;
  • Pills "Spilled";
  • Nimesan in tablet form.

Some drugs are complete analogues in the amount of active substance, while others - the ratio of nimesulide varies. From this, the indications and prohibitions on the use of medicines change.

If for any reason it is necessary to choose another drug from the NSAID group, the range of drugs is wide. The choice depends on the genesis and characteristics of the pain.

Relieve pain and inhibit inflammatory processes:

  • Diclofenac
  • Sinarta;
  • "Meloxicam";
  • "Artromax";
  • Mucosat;
  • Glucosate
  • "Movex";
  • Ibuprofen
  • Chondroxide;
  • "Aspirin".

Tablets, ointments, gels, capsules and granules - a different form of drugs allows you to choose the best option for each individual case to quickly and effectively eliminate pain.

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