“Ibuprofen” is a popular drug distributed around the world that has anti-inflammatory properties and is used to lower fever and relieve pain. In medical practice, ibuprofen-based medicines have been used since 1970. In just a few years, the drug gained the title of the best analgesic. Today, Ibuprofen and its analogues are widely used in pediatrics and general medicine. Its effectiveness in the fight against hyperthermia is clinically proven. It is safer than acetylsalicylic acid. Separate forms of the medication can be used to treat babies from the age of 3 months.
Material Content:
Release forms and composition
Ibuprofen is a substance that is obtained from the processing of phenylpropionic acid. It is a modern analgesic, anesthetic. According to pharmacokinetic properties, it is classified as a non-steroidal anti-inflammatory drug. The medication is made in several forms. The amount of active ingredient (ibuprofen), as well as a set of auxiliary ingredients, depends on the form of release.
- Film-coated tablets (200 mg, 400 mg). Medicines contain stearic acid, cellulose microcrystals, starch, talc, polysorbate 80.Tablets are placed in blisters of 10 pieces, packed in cardboard boxes.
- Effervescent tablets with lemon flavor (200 mg) in plastic tubes of 10 or 20 pieces. The composition includes aspartame, sodium saccharin, simethicone.
- Suppositories (60 mg), 5 pieces per cell. An auxiliary component is solid fat.
- Syrup with orange or strawberry flavor in 100 ml bottles. The dose (5 ml) contains 100 mg of ibuprofen. The composition also includes sorbidol, glycerol, citric acid, water, flavoring, etc.
- Ointment with an active substance content of 5% in tubes of 25 g, packed in a cardboard box. The product has a specific smell and a yellowish color.
- The gel (5%) contains purified water, lavender oil, propylene glycol. The product for external use is placed in an aluminum tube with a volume of 20 - 100 g.
The price of the drug and the treatment regimen depend on the form of release. Each preparation is accompanied by instructions for use. Be sure to familiarize yourself with it before starting the course.
Pharmacological action and pharmacokinetics
"Ibuprofen" is a drug from the clinical and pharmacological group of NSAIDs, which has a pronounced anti-inflammatory effect, normalizes temperature, and has analgesic properties. The principle of action of the drug is the ability of the active component to inhibit the production of prostaglandins. These are the vehicles of pain, hyperthermia and inflammation.
The maximum concentration of ibuprofen in blood plasma is reached after 45 minutes, provided that the drug is taken on an empty stomach. About 90% of the active substance combines with plasma proteins and is distributed throughout the body, decomposing in the liver. The component is excreted by the kidneys and bile.
What helps ibuprofen
The drug "Ibuprofen" is indicated for various diseases that are accompanied by pain, hyperthermia.
It is advisable to use a medication for such violations:
- degenerative changes in bone and muscle tissue;
- arthritis of various origins, sciatica;
- toothache;
- migraine;
- pains that accompany menstruation in women;
- post-traumatic syndrome;
- postoperative period;
- inflammation and pain in cancer;
- algodismenorea;
- fever for infections and colds, etc.
Ibuprofen tablets, suspension or suppositories do not affect the course of the disease.
The drug relieves symptoms, but does not eliminate the cause of the pathological process.
Instructions for use and dosage for children and adults
The dosage regimen of the drug depends on the symptoms and specifics of the disease. Ibuprofen is available without a prescription, but this does not mean that you can self-medicate. The instructions describe in detail the regimen of taking the medication for various diseases.
Before starting the course, you should consult your doctor. In some cases, the use of "Ibuprofen" must be combined with the use of drugs from other pharmacokinetic categories, so as not only to relieve symptoms, but also to remove the cause of the disease.
200 mg and 400 mg film-coated tablets
Ibuprofen tablets are prescribed for adult patients and children over 12 years old. Medicines must be swallowed whole without chewing. You can drink a little liquid. A single dose is 400 mg, daily - 1200 mg (for children - 1000 mg). The minimum interval between doses is 4 hours. If within 2 to 3 days the symptoms have not been removed, you should consult a specialist to determine the cause of the disease and develop complex therapy.
Rectal suppositories for children 60 mg
Candles "Ibuprofen" - the best choice for the treatment of pediatric patients. The dosage is calculated from a ratio of 5 to 10 mg per kg of body weight. The daily dose should not exceed 30 mg / kg.If the drug is used for fever, the duration of admission is a maximum of 3 days, if as an anesthetic - 5 days.
Gel for external use 5%
Wash hands with soap before use. Squeeze a small amount of the product from the tube, treat the painful area. The interval between procedures is 4 hours.
Do not apply Ibuprofen gel on damaged skin.
After the procedure, you must also wash your hands thoroughly, because the gel can cause severe irritation if it accidentally gets on the mucous membrane or in the eyes.
Ointment for external use 5%
Ibuprofen ointment relieves inflammation and relieves pain. You can use it, like gel, if the integrity of the skin is not broken. The product must be applied to the skin and rub with massage movements until it is completely absorbed. Processing can be carried out up to 4 times a day with a break of 4 hours.
Syrup or suspension for oral administration
The dosage for babies aged 3 months to a year is 2.5 ml, 1-3 years old - 5 ml, 4-6 years old - 7.5 ml, 6-9 - 10 ml, 9-12-15 ml. The interval between doses is 6-8 hours. Before giving the medicine to the child, you need to shake the bottle well until a homogeneous mixture is obtained. It is recommended to take Ibuprofen syrup after meals, you can drink it with water. The package has a measuring cup for accurate dose determination.
During pregnancy and lactation
Pregnant women, as well as those who are preparing to conceive a child, can not use Ibuprofen. The use of this drug in late pregnancy can lead to fetal pathologies due to cardiopulmonary toxicity. For the future mother, the use of the drug threatens the development of bleeding.
Admission "Ibuprofen" in early pregnancy can provoke a miscarriage.
Ibuprofen in small amounts penetrates into the mother’s milk, therefore, during lactation, this medication should be used with extreme caution.
Drug interaction
Ibuprofen is not indicated for patients who take acetylsalicylic acid or other NSAIDs. Violation of this recommendation may lead to or exacerbate coronary insufficiency.
Do not combine the use of "Ibuprofen" with the use of drugs from the following pharmacokinetic categories:
- thrombolytic drugs;
- anticoagulants;
- cyclosporine;
- valproic acid;
- calcium secretion blockers;
- antidepressants;
- vasodilators;
- antiplatelet agents;
- fibrinolytics;
- mineral corticosteroids;
- antacids and others
It is not recommended to combine ibuprofen-based medication with alcohol-containing drinks. The likelihood of developing adverse reactions increases.
Caffeine enhances the analgesic effect.
Contraindications, side effects and overdose
The drug is contraindicated in patients with hypersensitivity to its main or auxiliary components. Ibuprofen is not prescribed for patients with peptic ulcer during exacerbation, with inflammation of the digestive tract, liver and kidney pathologies, during pregnancy. You can not take the drug if hemophilia and other pathologies of the hematopoietic system are diagnosed.
Admission of "Ibuprofen" may be accompanied by such side effects:
- digestion disorder;
- headache, drowsiness, irritability;
- decreased performance, poor health;
- allergic reactions;
- bronchospasm, shortness of breath;
- heart palpitations;
- dizziness, loss of consciousness;
- exacerbation of renal failure, etc.
In case of an overdose, blood pressure decreases, inhibition occurs, severe pain in the stomach.
Exceeding the dose poses a danger to the life and health of the patient, because it can lead to tachycardia, respiratory arrest, atrial fibrillation. It is urgent to call an ambulance.
In a hospital, gastric lavage is performed, activated charcoal or another sorbent is prescribed. To quickly overcome intoxication, you need to drink a lot, including alkaline drinks. To stabilize the patient’s condition, symptomatic therapy is also carried out, which can be aimed at normalizing vital signs (heart rate, pressure, temperature).
Antipyretic analogues
The pharmaceutical market offers a wide range of ibuprofen-based drugs. Even more drugs with a similar mechanism of action, but with a different composition. Below is a list of the most popular and effective analogues of Ibuprofen.
- "Artrokarm" is used to treat pathologies of the musculoskeletal system.
- “Next” is a combined preparation, which, in addition to ibuprofen, also includes paracetamol.
- Ibunorm costs only 30-60 rubles, although it contains the same components as Ibuprofen.
- Ibufen is a Polish preparation with an improved composition that has fewer contraindications and is better tolerated by patients.
- Syrup "Nurofen" is widely used in pediatrics, can be given to children from 3 months. The product has a pleasant fruity taste and aroma.
- Diclofenac is a relatively low-cost, effective drug, available in the form of capsules, tablets, ointments, gel, injection.
This is not the whole list of substitutes. To choose the most suitable medicine, you should contact a specialist for advice, pass tests and wait for their results. The maximum therapeutic effect can only be achieved if the patient follows the doctor’s instructions or at least gets acquainted with the instructions for use.
