Flemoxin Solutab 500 mg is one of the few antibacterial drugs that has a minimal set of contraindications and an effective anti-inflammatory algorithm. Prescribing a medication is allowed for both adult patients and children in the first year of life.
Material Content:
- 1 Composition, active substance
- 2 Pharmacological action, pharmacodynamics and pharmacokinetics
- 3 In which cases Flemoxin Solutab 500 mg is prescribed
- 4 Instructions for use and dosage for children and adults
- 5 During pregnancy and lactation
- 6 Drug interaction
- 7 Can I drink alcohol while taking the drug
- 8 Contraindications, side effects and overdose
- 9 Antibiotic Analogs
Composition, active substance
The basis of the drug is amoxicillin. This is a semi-synthetic antibiotic belonging to a number of penicillins. It has high absorbent properties, is resistant to acids, and has low toxicity.
It is produced in the form of dispersible (water-borne) tablets of elongated rounded shape with a cross section. Both oral administration and preliminary dilution of the drug with a small amount of water are allowed. Due to this, accelerated absorption of substances occurs and the process of use by the smallest patients is facilitated. The medication is white and contains the marking "234", which means that the drug contains 500 mg of the active component - amoxicillin.
Along with it, the antibiotic Flemoxin Solutab consists of substances:
- crospovidone;
- magnesium salts of fatty acids;
- cellulose (dispersible and microcrystalline);
- vanillin;
- flavorings "citrus";
- crystalline sodium hydrate.
The tablets are sealed in a blister of 5 units. One package of the medication contains 20 tablets and an annotation for taking the drug.
Pharmacological action, pharmacodynamics and pharmacokinetics
The drug gives a strong bactericidal effect against a number of gram-positive and gram-negative microorganisms. Amoxicillin inhibits the formation of peptidoglycan (a component of the pathogen membrane), which results in the destruction and death of the bacterium.
The medication is effective against the following microorganisms:
- E. coli;
- streptococcus;
- staphylococcus;
- Salmonella
- gonococcus;
- Shigella
- meningococcus
- clostridia;
- tetanus bacillus;
- Klebsiella.
Taking the drug is useless against microbes that produce beta-lactamases.
Flemoxin Solutab 500 tablets have fast and high absorption. The drug is absorbed by almost 93%, after 2 hours a maximum of active substances is observed in the blood. Eating food does not affect the degree of assimilation of the medication, which allows it to be consumed at any convenient time.
Active substances penetrate perfectly into:
- blood plasma;
- mucous membranes;
- sputum;
- bone tissue;
- intraocular fluid;
- amniotic fluid and umbilical cord vessels.
Amoxicillin is excreted by the kidneys. The half-life in adults is 1.5 hours, in children younger than six months from 3 to 4 hours.
In which cases Flemoxin Solutab 500 mg is prescribed
Indications for taking the drug are for patients who are diagnosed with one of the following diseases:
- urinary tract infections;
- pneumonia;
- otitis;
- bronchitis;
- tonsillitis (tonsillitis);
- sinusitis.
When diagnosing sinusitis in a patient, Flemoxin Solutab is one of the first to be prescribed. This is due to the fact that the causative agent of inflammatory processes of the sinuses are staphylococci and streptococci, the development of which successfully blocks amoxicillin. And in view of the fact that the drug has a unique fast absorption, improvement of well-being is observed already on the next day after the start of taking the antibiotic.
The medication is effective against pneumonia and pneumonia, because Streptococcus pneumoniae is the cause of the disease. Amoxicillin-containing drugs quickly recognize and destroy it. The use of Flemoxin Solutab therapy is a 90% guarantee of a complete cure for the patient. However, in rare situations, medication may be ineffective. This occurs in cases where the causative agent is a strain that produces the penicillinase enzyme. It negates the effect of penicillin. In the presence of such microorganisms, the drug is replaced.
The tool is very often used in pediatrics for the treatment of tonsillitis. The cause of the disease are microorganisms: streptococci and staphylococci, the main weapon against which is amoxicillin. An additional incentive for the appointment of small patients Flemoxin Solutab is the presence of fragrances in the composition, which gives the tablet a pleasant taste.
In addition, the drug is effective for otitis media. However, due to the inaccessibility of the focus of infection, the use of the drug is prolonged, in order to avoid exacerbation.
Despite the almost complete absence of contraindications, self-administration of Flemoxin Solutab is prohibited. Properly identify the type of pathogen that caused the disease, and only a specialist can choose the right treatment algorithm.
Instructions for use and dosage for children and adults
Instructions for use Flemoxin Solutab contains information on the dosages and duration of use of the medication. In addition, it states that children under the age of 1 year are allowed to take the drug.
The medication is intended for oral administration. The time of eating food while drinking the medicine does not affect.
There are several ways to use the product:
- swallowing, followed by drinking water;
- pre-grinding tablets before swallowing;
- drink in the form of syrup (when the tablet is diluted in 20 ml of water);
- use in the form of a suspension (dilution ratio in water 1: 100).
The dosage is set by the attending physician and depends on the age of the patient, the form of the disease and the general physical condition and characteristics of the body.
Standard reception scheme:
- Children of the first year of life 30-60 mg per each kilogram of patient weight. The specified amount of the drug is divided into 2 or 3 use.
- Kids up to 3 years of age can take 250 mg twice a day or 125 three times.
- Patients from 3 to 10 years - 375 mg twice or 250 mg three times a day.
- For adults, the drug is prescribed for 500-750 mg. The maximum possible daily dosage is 3 g of amoxicillin.
For uncomplicated diseases, Flemoxin Solutab should be taken from 5 to 10 days. If the disease is chronic or acute, the drug should be taken three times a day. The duration of therapy depends on the reaction of the body to the medication. As a rule, after the disappearance of the symptoms of the disease, experts recommend drinking Flemoxin for another two days.
For patients with renal dysfunction, the drug is prescribed with adjustments in the form of a 15-50% reduction in consumption.
During pregnancy and lactation
Although the active substances of the drug quickly penetrate into the blood plasma and easily pass the placental barrier, studies have not revealed a negative effect on the embryo. Therefore, the use of Flemoxin Solutab during pregnancy is allowed. However, this should be done only as directed and under the supervision of a doctor.
Treatment during lactation is also allowed, because amoxicillin passes into breast milk in small volumes. To ensure safety for several days, the child can be transferred to artificial feeding, and after completion of therapy, resume the natural regimen.
Drug interaction
The combination with some medicines can increase the concentration of active substances in the blood and the half-life. Such drugs include aspirin, probenecid, Sulfinpyrazone, thunderyl, phenylbutazone.
Flemoxin Solutab reduces the reliability of the action of contraceptives containing estrogen, as well as sulfonamides and chloramphenicol. May enhance concomitant adverse effects of bactericidal antibiotics.
Can I drink alcohol while taking the drug
Concurrent use of Flemoxin Solutab with alcohol will negate the work of the antibiotic, since alcohol has a diuretic effect. This will lead to too rapid withdrawal of amoxicillin from the blood. The drug enhances the side effects of drinking, which is manifested in the appearance of nausea and vomiting reflexes.
In addition, a double burden is imposed on the liver - the processing of an antibiotic and alcohol. As a result, harmful substances and toxins accumulate in the body, leading to such serious diseases as cirrhosis and hepatitis.
Contraindications, side effects and overdose
Flemoxin Solutab has contraindications:
- atypical reactions to the components of the drug;
- liver or kidney dysfunction;
- seasonal allergic rhinoconjunctivitis;
- chronic inflammatory diseases of the bronchi;
- lymphocytic leukemia;
- pathological features of the digestive tract;
- mononucleosis;
- diathesis.
In rare cases, side effects may occur.
They appear in the form of:
- dyspeptic disorders (diarrhea, vomiting, nausea);
- rash and other allergic reactions to the skin;
- dysbiosis (excluded with the simultaneous use of probiotics).
The occurrence of severe diarrhea is a serious reason for canceling the therapy used.
With an overdose, side effects increase and are accompanied by general dehydration of the body. When it occurs, laxatives are prescribed, which are based on salts, as well as enterosorbents. Along with this, measures are being taken to normalize the body’s water-salt balance.
Antibiotic Analogs
Like any good medication, Flemoxin has a number of drugs with a similar algorithm of action.
Analogs of the drug:
- Sumamed;
- Flemoklav Solutab;
- Amoxicillin;
- Amoxiclav;
- Suprax;
- Augmentin.
Despite the large number of similar drugs, only the attending physician can replace one medication with another. Only in this case there is a guarantee of recovery and the exclusion of relapse of the disease.