In the modern world, every fifth person is in a neurotic or psychopathic state, which is accompanied by anxiety, insomnia and emotional instability. "Phenazepam" is one of the most effective drugs for the treatment of such conditions. However, it is worth remembering that you should not prescribe such drugs yourself, and the doctor determines the dosage of "Phenazepam" in each case.

Composition (active substance) and release form

"Phenazepam" is a drug from the group of benzodiazepines, which belong to psychoactive substances. It contributes to fast falling asleep and restful sleep, the cessation of voluntary muscle contractions (stops cramps). It has a sedative effect.

The active substance of the drug is bromodihydrochlorophenylbenzodiazepine, which has the form of a white powder and does not dissolve in plain water. By its chemical structure, Phenazepam is a benzodiazepine tranquilizer and was first produced in the Soviet Union in the 1970s. It has a powerful sedative effect, which makes it the strongest drug among all tranquilizers (benzodiazepine and abenzodiazepine).

On sale you can find "Phenazepam" in tablets (flat, white) labeled and "Phenazepam" in solutions for injection and infusion (a clear, odorless liquid).

The composition of the medicine includes:

  • the active substance is bromodihydrochlorophenylbenzodiazepine (0.5, 1, 2.5 mg in each tablet and 1 mg in 1 ml of solution);
  • additional components - lactose, sodium, calcium stearate, povidone, water, polysorbate, sodium hydroxide.

You can buy medicine only by prescription, which also determines the dosage individually for each patient. Tablets are packed in blisters of 10 - 25 pieces or in a plastic bottle of 50 pieces. Phenazepam in ampoules and glass vials is also available at pharmacies.

Pharmacological properties and indications for use

"Phenazepam" has a sedative and hypnotic effect, and also has an anticonvulsant and anxiolytic effect. It slows down the transmission of impulses in nerve cells, which leads to a calming of the nervous system.

The medication is also capable of:

  • stimulate benzodiazepine receptors;
  • reduce the susceptibility of the limbic system (reduce the feeling of fear and anxiety);
  • reduce emotional arousal;
  • slow down spinal reflexes.

A calming effect is achieved by influencing brain cells and reducing symptoms of a neurotic nature.

When taking the drug inside, it is perfectly absorbed into the bloodstream from the gastrointestinal tract and reaches the maximum possible concentration after 1.5 hours. It breaks down into metabolites in the liver and is excreted by the kidneys 10 to 18 hours after ingestion.

The doctor prescribes a medication if the patient has:

  • states of neurosis and psychosis of a different nature;
  • constant feeling of anxiety and fear;
  • dysfunctions of the autonomic department of the central nervous system;
  • insomnia;
  • epilepsy (myoclonic or temporal).

Take "Phenazepam" as a preventive medicine with a constant feeling of fear or emotional instability. Permission to use the drug is given by the attending physician after an accurate diagnosis.

Instructions and dosage in tablets and ampoules

The course of treatment with "Phenazepam" lasts 14 days, since with a longer treatment course there is a risk of developing drug addiction.

Take "Phenazepam" orally for home therapy or in the form of injections and droppers during hospitalization.

Dosage depends on the diagnosed disease:

  1. In case of sleep disorders: 0.5 mg with a single dose 30 minutes before bedtime.
  2. Conditions of neurosis, psychopathic disorder: the first 4 days of therapy - 1 mg 3 times a day, the remaining days - 4-6 mg per day.
  3. Constant feeling of anxiety: in the first 3 - 4 days - 3 mg per day, increasing in the next days of therapy by 1.5 - 3 mg.
  4. Epilepsy: the medication is used as a remedy for seizures from 2 mg to 10 mg per day.
  5. The development of withdrawal symptoms (neurotic disorder): 2-5 mg per day.

The daily dose for a person should not exceed 10 mg, while it must be evenly divided into doses of 1.5 - 5 mg. It is not worth taking more than this amount so that drug dependence does not develop. After the end of the course of treatment, it is sharply impossible to cancel the drug, because the patient may develop withdrawal syndrome.

During pregnancy and lactation

Admission of the phenazepam tranquilizer is strictly forbidden to women who are in a position or who are breast-feeding a baby!

The attending physician can authorize the use of the drug only as a last resort with a risk of death or serious violations for a woman. In this case, it is worth knowing that the medicine has a toxic effect on the child and provokes the development of pathological abnormalities in his womb. In the second and third trimester, the medicine can depress the central nervous system of the child, and constant use during this period will cause drug dependence in the mother.

During breastfeeding, the drug enters the baby's body through breast milk and has an inhibitory effect. The use of the medication before labor can provoke respiratory depression and a decrease in muscle tone in the child.

Influence on the ability to drive vehicles and control mechanisms

Despite the fact that “Phenazepam” is a tranquilizer, in the Russian Federation it is not included in the list of narcotic drugs and drugs with limited distribution. Legislatively taking the drug before driving is allowed, but it is best to refrain from driving the vehicle and any mechanisms within 18 hours after administration, since the drug can cause a slowdown in the reaction.

Phenazepam Compatible with Alcohol

It is unacceptable to take "Phenazepam" and alcoholic beverages together, since the active substance of the medication enhances the alcoholic effects, namely intoxication, clouding of consciousness, respiratory depression. The combined use of a tranquilizer and alcohol can lead to coma, respiratory arrest and death.

In addition to alcohol, it is unacceptable to take "Phenazepam" together with antipsychotics, sleeping pills, analgesics and antidepressants. The active substance bromodihydrochlorophenylbenzodiazepine can enhance their effect and cause pathological processes in the body.

Contraindications, side effects and overdose

The attending physician, before the appointment of "Phenazepam," in case of panic attacks or other disorders, is required to clarify whether the patient has contraindications for admission.

Their list includes:

  • allergy;
  • state of shock;
  • glaucoma;
  • alcohol intoxication;
  • drug intoxication;
  • lung disease or respiratory failure;
  • diagnosed depression.

It is unacceptable to use the drug for children and adolescents under 18 years of age, and also to use it for patients in a coma.

With caution, it should be taken also by patients with impaired renal and hepatic functions, as well as drug dependence in the past.

Among the possible side effects are observed:

  • drowsiness and dizziness;
  • disorientation;
  • slowing down the reaction;
  • anemia;
  • nausea and vomiting;
  • heartburn;
  • rash or itching;
  • changes in libido;
  • visual impairment.

If the dosage and method of taking “Phenazepam” are not observed, the patient may develop an overdose, the symptoms of which are manifested in confusion, depression of cardiac activity, drowsiness and tremor, shortness of breath and shortness of breath.

In case of overdose, immediately wash the patient’s stomach, monitor vital signs and conduct symptomatic therapy.

OTC analogues

Structural analogues of "Phenazepam", ie, the same in terms of the active substance used, are:

  • "Phenorelaxan";
  • "Elzepam";
  • "Fezanef."

The same effective drugs, but without a lot of side effects are:

  • "Etaperazin";
  • "Glycine";
  • Sonapax

These medicines can be purchased without a doctor’s prescription, but the dosage should be observed to avoid manifestations of side effects.

"Phenazepam" is a powerful tranquilizer, which is used to treat not only neurosis and psychosis, but also to calm the nervous system, and also as an anticonvulsant as part of therapy for epileptics. It should be taken only by decision of the attending physician and strictly observing the dosage.

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