A sense of anxiety, a feeling of internal tension, psychological discomfort are conditions familiar to many. You can choose the analogues of "Phenazepam", acting softer than a strong tranquilizer, not causing drowsiness and addiction. They will help you work normally and enjoy your vacation, calmly communicate with colleagues and family members.
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Composition (active substance) of Phenazepam
The drug belongs to the group of benzodiazepines, which is clear from the full name of its active substance - bromodihydrochlorophenylbenzodiazepine. The composition of the tablets "Phenazepam" may contain 250 or 500 μg, 1 or 2.5 mg of this compound. The concentration of the drug in solution is 1 mg / ml. The drug in liquid form is used for intravenous or intramuscular administration.
The active component of the drug is a highly active tranquilizer, a powerful anxiolytic agent. Benzodiazepine inhibits the spread of nervous excitation in the central nervous system when interacting with gamma-aminobutyric acid receptors. "Phenazepam" relaxes skeletal muscles, has an anticonvulsant effect.
Analogs and substitutes of the drug
In addition to the trade name Phenazepam, other commercial names are used for the same substance. Full analogues are the tablets "Phenorelaxan", "Elzepam", "Fenzitat".Preparations contain 0.5 or 1 mg of active substance.
"Phenazepam" and its structural analogues are sold in pharmacies only by prescription.
In addition to benzodiazepines, barbiturates, antidepressants and antipsychotics have a strong anxiolytic effect. As a rule, they are dispensed in pharmacies with a prescription. The first part of the term “anxiolytics” in translation means “fear”, “anxiety”, the second half of the word means “dissolving”. In parallel, the name tranquilizers - soothing.
Prescription anxiolytics and antidepressants (medications for treating mental disorders):
- Grandaxinum;
- Atarax
- Phenibut
- "Adaptol";
- "Stresam."
Medications reduce anxiety, suppress phobias, reduce emotional stress, help cope with insomnia. Instead of drugs with a large number of negative manifestations come safer modern analogues.
OTC
Benzodiazepines and barbiturates are gradually replaced by non-benzodiazepine anxiolytics combined with phytopreparations. By over-the-counter analogues of "Phenazepam" according to the mechanism of action, "Afobazole" refers. The tool reduces or completely eliminates anxiety, a sense of anxiety, fear. "Afobazole" helps with a depressed mood, difficulty concentrating, emotional lability. The price in the pharmacy is 370 rubles.
"Tenoten" and "Glycine forte" are substitutes for "Phenazepam" with a decrease in memory, nervousness and emotional stress. Drugs can be taken by children.
- "Tenoten", in addition to anxiolytic action, has a nootropic effect - improves brain function.
- “Glycine” is the most affordable sedative and nootropic drug. The cost of packaging (100 pcs.) - 65 rubles.
- "Persen" - a sedative phytomedicine in tablets. The drug contains extracts of medicinal plants. "Persen" eliminates the symptoms of neurosis, makes falling asleep easier. The medicine is used for depressive mood, increased anxiety, irritability, stress and insomnia.
- Drops "Valocardine" and "Corvalol" contain phenobarbital, have a sedative effect, but are devoid of the negative effects inherent in barbiturates. "Valocardin-Doxylamine" has a hypnotic effect. It is a histamine H1 receptor blocker. The drug helps with sleep disorders caused by allergies, inflammation, pain.
Non addictive
Benzodiazepines can cause dependence in humans. Gentler, compared with Phenazepam, are the non-addictive Atarax and its generic Hydroxysin Canon (they are prescribed by doctor's prescription). These anxiolytics help with various anxiety conditions, depression, panic attacks, withdrawal symptoms.
“Phenibut” and its generics “Noofen” and “Anvifen”, “Adaptol” also belong to anxiolytics. Funds are dispensed in pharmacies only with a prescription. The cost of packing tablets is from 200 to 600 rubles.
Cheap Russian analogues
Phenazepam tablets in a pharmacy can be bought if there is a doctor’s prescription. The cost of packaging is 130 rubles. Other Russian drugs that are produced using the same active substance: Phenorelaxan, Tranquesipam, Elzepam and Fenzitat. These structural analogues are cheaper or available at the same price as Phenazepam.
Generics of foreign manufacture
Phenazepam can be replaced with other benzodiazepine derivatives.
- Diazepam and tofisopam are more popular abroad.
- Generic "Phenazepam" is produced in Belarus. The name of the tablets is Arpazepam.
- Polish medicine “Relium” contains diazepam. It is used for neurosis, anxiety, neurosis-like conditions, alcohol withdrawal, epilepsy.
- With the same indications, Seduxen is prescribed - a preparation of joint Russian-Hungarian production.
- Grandaxin tablets are produced in Hungary. The active substance is tofisopam.This benzodiazepine derivative differs from “Phenazepam” in that it acts milder, does not cause the development of addiction and withdrawal syndrome. "Grandaxinum" is the so-called daily anxiolytic.
- Stresam capsules are available in France. The active substance is etifoxin. The drug is used to reduce feelings of anxiety, eliminate internal stress, fear, get rid of nervousness, irritability.
Instructions for use in tablets and ampoules
For problems with falling asleep, it is recommended to use "Phenazepam" with a dosage of 0.5 mg. Tablets should be drunk half an hour before going to bed. The instructions for use indicate the dose for other conditions and diseases. The maximum allowable amount of the drug per day is 10 mg.
To avoid addiction and the development of withdrawal syndrome, "Phenazepam" take no more than 2 weeks (as an exception - up to 2 months).
If you are worried about fear, anxiety, then at the beginning of treatment you should drink 3 tablets of 1 mg three times a day. Gradually, the daily dose can be increased. In neurotic and neurosis-like conditions, tablets are taken 0.5-1 mg 2 or 3 times a day. After a few days, you can increase the dose. With good tolerance, the presence of a positive effect is taken 4-6 mg / day.
The daily dose for alcohol withdrawal is 2 to 5 mg. This amount of the drug should be divided into 2 or 3 doses. In the evening, you can drink a 2.5 mg tablet.
"Phenazepam" in ampoules is prescribed for the same indications. Introduce the solution in / m or / in. Quick relief of anxiety is achieved by using an initial dose of 0.5 - 1 ml and the introduction of 3 - 5 ml / day solution (0.1%). In severe cases, 7 to 9 ml of the solution is prescribed. The drug is administered once or twice a day.
During pregnancy and lactation
"Phenazepam" increases the likelihood of congenital malformations in the fetus. The most dangerous to use the drug in 1 trimester.
If you drink tablets at a later stage of pregnancy, then the medicine inhibits the functions of the central nervous system of the child.
When using "Phenazepam" before and during childbirth, a decrease in temperature, pressure and muscle tone of the newborn is possible. The use of this medication during lactation has the same effect.
Phenazepam Compatible with Alcohol
The use of alcohol is strictly prohibited during the treatment with a tranquilizer. "Phenazepam" and alcohol are incompatible, as they increase the negative effect of each other, which leads to dangerous, sometimes irreversible, consequences. Drowsiness, depression, fear intensify, problems with breathing and heart function appear. Perhaps the development of seizures, coma.
Contraindications, side effects and overdose
"Phenazepam" is forbidden to take with hypersensitivity to benzodiazepines, as well as in life-threatening conditions (shock, coma, etc.). In addition, chronic obstructive pulmonary disease, myasthenia gravis, pregnancy and lactation are contraindications.
The drug is not prescribed for patients under 18 years of age.
Side effects are felt as opposed to a therapeutic effect. Instead of calm, lack of anxiety and clarity in the head - depressed mood, depression, low concentration of attention. Less common are paradoxical reactions in the form of fear, aggression, and insomnia.
In case of an overdose, difficulty breathing, a decrease in blood pressure and cardiac abnormalities, confusion. It is necessary to rinse the patient's stomach and give activated charcoal. In the hospital, detoxification is carried out using droppers.
The drug, which relaxes muscles, simultaneously inhibits cardiac activity and respiration. Anti-anxiety effect is combined with drowsiness, low concentration of attention. Phenazepam is not a very good choice. Often, after applying a tranquilizer, a person feels tired, broken. It is better to use modern non-benzodiazepine analogues of the drug or herbal sedatives.
