The question of why Duspatalin helps is of concern to many people who have been examined by a gastroenterologist. This drug acts as an effective myotropic antispasmodic for pain of a spastic nature, without violating the contractility of the walls and the general tone of the intestine.
Material Content:
Composition and release forms
In the composition of the antispasmodic medication, the main active compound is mebeverin hydrochloride.
The pharmaceutical product of the Dutch company Duspatalin is produced in several forms:
- 135 mg tablets;
- 200 mg capsules.
In Duspatalin 200 mg capsules, a higher content of active compound is present than in tablet form. And also these two forms differ in their component composition. So, the former are represented by the following set of additional chemical compounds: magnesium stearate, hypromellose, triacetin, lecithin and shellac. The following components are present in tablets: lactose monohydrate, talc, mania stearate, sucrose.
What helps Duspatalin
It is advisable to prescribe a medicine for painful attacks in the gastrointestinal tract, which are caused by spasm of smooth muscles.
As a rule, such pain attacks occur in the following cases:
- intestinal or biliary colic (or other etymology);
- manifestations of irritable bowel syndrome (the drug acts as an additional medication in complex therapy);
- hypertonicity of the sphincter of Oddi;
- pathological violation of the gallbladder;
- the condition of the gastrointestinal tract, which is accompanied by cramping and due to existing pathologies (e.g., pancreatitis);
- postoperative period after removal of the gallbladder;
- pathological disorder of the digestive tract.
The medication has a direct effect on smooth muscle, relaxing it and relieving spasm.
The pharmacological result of Duspatalin is expressed mainly in the large intestine, while a decrease in tone does not affect the natural contractility.
And it is also worth noting that a therapeutic agent is often prescribed to relax the sphincter of Oddi, which greatly improves the outflow of bile and relieves the arising pain.
After ingestion and absorption through the intestinal wall, the active composition of the drug is in the general bloodstream. Then, Duspatalin tablets are metabolized in the liver, and excretion is carried out through the kidneys.
Instructions for use and dosage
Since the dosage forms of Duspatalin include a different dosage, there are special instructions for the use of a medication.
135 mg tablets
This form must be taken in full 30 minutes before eating. A significant amount of liquid is recommended. The standard dosage is one tablet three times a day. The duration of treatment depends on the patient's history. The use of the drug stops after the complete elimination of the painful discomfort. Then the patient needs to gradually reduce the dosage, starting with 2 tablets per day. Upon completion, take one piece or even a half.
Capsules 200 mg
The encapsulated form is also used whole and washed down with the usual amount of liquid. Use the medicine should be 20 minutes before a meal. The standard treatment regimen involves two pieces per day.
Drug therapy continues until the pain is completely relieved.
Abrupt cessation can cause withdrawal syndrome, so it is necessary to gradually reduce the dosage.
To gradually discontinue use of the capsules, take the first week one at a time in the morning. Then the patient will have to completely abandon the medicine. The instructions for use indicate that with relapse and resumption of previous symptoms, a return to therapy according to the standard scheme is allowed.
In the case of pancreatitis, it is recommended to take Duspatalin twice a day - in the morning and in the evening. The duration of treatment also depends solely on the patient's condition and the manifestation of pain discomfort. After stopping the signs of the disease, the medication should be gradually withdrawn according to the standard scheme. The drug is recommended for chronic diseases to prevent acute exacerbations.
During pregnancy and lactation
As a rule, an indication for the appointment of Duspatalin during pregnancy is an excessive tone of the uterus. To eliminate the problem, No-shpa or Papaverine are prescribed, but quite often there is a need for taking an antispasmodic. It is worth considering that with hypertonicity, this tool will be ineffective. Often, this drug is recommended for use with spasm of the sphincter of Oddi, since such a disorder can cause pain and problems with the outflow of bile.
Many studies have been conducted, the purpose of which was to identify and evaluate the influence of the main component on the fetus. According to their results, it was established that Duspatalin is not able to have a negative effect on the fetus, and also does not pose a threat to a woman in position. However, its independent appointment is not allowed - in any case, it is required to discuss the issue of admission with a doctor. The tablet form is strictly contraindicated, and the capsules should not be combined with other medicines with a similar effect.
During pregnancy, the standard dosage is two capsules per day. One reception is needed in the morning, and the second in the evening. The duration of therapy is determined by the existing violation. To cancel the drug, you will need a two-week intake of Duspatalin in one capsule. A medication can be prescribed in advance if spasms of the sphincter of Oddi have been noted in the past. This is due to the fact that a disease of the pancreas of a chronic course is often manifested.
Drug interaction
In the course of the studies, it was found that the main active compound of Duspatalin is unable to interact with other drugs. Based on this, a therapeutic agent is allowed in combination with other medicines. According to the instructions for use, Duspatalin is strictly forbidden to combine with drinks containing ethanol. Otherwise, there is a risk of increased pain and a decrease in the effectiveness of the medication.
Contraindications, side effects and overdose
Duspatalin is characterized by a small number of contraindications, which include the age of children under 12 years old, as well as an inadequate reaction of the immune system to an irritant, which is manifested by allergies. It is allowed to use during lactation, since the main compound is not excreted in milk in higher concentration. Undesirable reactions due to the appointment of funds, occur quite rarely.
Among them, the following phenomena were noted:
- Migraine and dizziness.
- Attacks of nausea, upset stool and digestion.
- Skin allergic manifestations: urticaria, severe itching, swelling.
And it is also important to note that in some cases, the medicine may affect the ability to work with complex mechanisms, to drive a car. Therefore, during treatment, it is recommended to limit the activity, which will require an increased concentration and reaction rate. In case of an overdose, negative manifestations appear in an enhanced form. In this case, the victim will need a gastric lavage and subsequent treatment of certain symptoms.
Cheap analogues Duspatalin
Duspatalin analogs are produced by many pharmaceutical corporations, individual synonyms are quite low cost. Substitutes that have a similar therapeutic effect include Sparex, Trigan, and Niaspam. Such antispasmodics include Dietetel, Drotaverin, Nosh-pu. The selection of a similar media piece must be discussed with a specialist.
