Dufaston is a synthetic progesterone (progestogen), the use of which is aimed at combating progesterone deficiency. With the restoration of the hormonal background and the reproductive function of a woman, the drug copes quite successfully, but not everyone can afford treatment with it. Therefore, it will be useful to understand the purpose of the drug, instructions for taking, contraindications for its use and analogues of Dufaston.

Composition (active substance) of Duphaston

The composition of Duphaston includes:

  • the main substance is dydrogesterone;
  • lactose monohydrate;
  • starch;
  • fumed silica;
  • stearic acid;
  • E171;
  • agalite.

This combination of components controls the correct development of the endometrium and suppresses estrogen, restoring the amount of female hormones.

Tablets are packaged in blisters in an amount of 20 pieces.

Cheap Russian analogues

The average cost of the drug is 600 rubles. Such a price of the drug determines the demand for cheap analogues of Dufaston.

The following drugs are considered to be substitutes for Duphaston:

  1. "Progesterone". Its action is aimed at normalizing the environment for the development of the egg. The tool is available in the form of a solution for intramuscular administration. Price - from 570 rubles.
  2. Pregnin. It prepares the endometrium for egg implantation, reduces uterine tone and has a positive effect on lactation. Pregnin is available in tablet form. Price - from 400 rubles.
  3. Dydrogesterone is an active ingredient in Dufaston. Possible reception during pregnancy. Price - from 450 rubles.
  4. "Ingesta." A progesterone-based drug for the treatment of amenorrhea, uterine bleeding and infertility."Ingesta" helps to maintain pregnancy and has a minimum of contraindications. Price - from 95 rubles. (the cheapest Russian analogue of Duphaston in the pharmaceutical market).

Of foreign analogue funds, Utrozhestan (Belgium) is most popular. But the drug is clearly inferior to Duphaston because of the large list of side effects (drowsiness, headaches, increased fatigue, etc.).

Reception of any analogue means must be approved by the attending physician.

Instructions for use of the drug

Taking Duphaston tablets entails the absorption of dydrogesterone into the blood. Further, the substance is evenly distributed throughout the body, having a direct effect on reproductive function. Use the drug at the dosages recommended by the doctor, since they are prescribed based on many factors (pathology, the presence of menstruation, etc.).

Summarized recommendations for admission are as follows:

  1. 10 mg of the drug several times during the day for 20 days with endometriosis.
  2. 4 tablets at the first dose and 1 every 8 hours if there is a risk of spontaneous abortion.
  3. 10 mg twice a day until the 20th week of pregnancy in case of a threat of miscarriage with the usual miscarriage.
  4. 1 tablet once a day in the middle of the cycle with infertility associated with insufficiency of the corpus luteum of the ovary.
  5. 1 pill twice a day in the middle of the cycle with irregular periods or premenstrual syndrome.
  6. 1 tablet twice a day for 20 days with painful menstruation (dysmenorrhea).
  7. 1 capsule twice a day for a week with dysfunctional uterine bleeding. Therapy can also be prescribed as a prevention of the recurrence of the problem.

During harmonious replacement therapy, Duphaston tablets are prescribed in combination with estrogens.

Also, instructions for taking the drug voices a list of important instructions:

  • after the start of using the medication, breakthrough uterine bleeding is possible, stopped with an increased dose of the drug;
  • with complex therapy using estrogen, side effects and contraindications should be taken into account;
  • before taking the drug, you need to undergo a complete medical examination to determine pathologies, features of the pelvic organs and possible negative reactions to the components of the drug;
  • "Duphaston" during pregnancy is allowed only with indications and under the supervision of a doctor;
  • if the medication is taken during lactation, during this period, breastfeeding will have to be minimized;
  • with tumor neoplasms in the patient, it is important to conduct a series of studies aimed at determining the reaction to dydrogesterone;
  • Duphaston does not affect driving and coordination.

In pharmacies, medication is dispensed only by prescription. His spontaneous intake can result in serious consequences.

The combination of dydrogesterone and ethanol is unacceptable. The result of this combination will be a decrease in the effectiveness of the drug and possible side effects.

The medication should be kept out of the reach of children, protecting from moisture and sunlight, no longer than 5 years from the date on the spine of the package.

Duphaston during pregnancy

Reception "Dufaston" during gestation is permitted only by agreement with the doctor. This drug helps many women with reproductive system problems maintain a healthy pregnancy, eliminating the risk of spontaneous abortion.

Contraindications, side effects and overdose

In rare cases, when taking Duphaston, patients may develop hemolytic anemia.

Also, a woman may experience the following side effects:

  • breakthrough bleeding;
  • frequent headache;
  • itchy skin;
  • swelling of the breast tissue;
  • nettle rash;
  • swelling of the extremities;
  • icteric syndrome, as a result of impaired liver function.

If after increasing the dosage of the medication to stop breakthrough bleeding it does not stop, then a woman should immediately seek medical help. Specialists will conduct an examination and conduct a biopsy of the uterine membrane to exclude a tumor. If there are no obvious reasons for bleeding, Duphaston is replaced with analogues containing natural progesterone.

In case of an overdose of dydrogesterone, the victim is recommended to do a gastric lavage, and then take antisymptomatic or adsorbing agents.

Duphaston is contraindicated in the following pathologies:

  • impaired liver function;
  • hypersensitivity to dydrogesterone;
  • metabolic disease;
  • kidney disease
  • lactase deficiency;
  • malabsorption syndrome;
  • galactose intolerance.

The use of hormonal drugs is strictly prohibited for their own purposes. Be sure to consult a doctor to rule out contraindications.

Related:More from the author: