Diuver is a delicate diuretic. It, unlike the bulk of diuretics, is not dangerous for patients with pathologies of the cardiovascular system, since it does not wash out potassium and does not cause hypokalemia. But this does not make it less effective; within a few hours, the drug removes excess water from the body. Indications for use Diuver are pathological conditions that are accompanied by accumulation of fluid in the tissues, edema, for example, heart or kidney failure, arterial hypertension.

Release form and composition of the drug

There is the only form of Diuver's release - tablets, they can contain 5 or 10 mg of the active substance, depending on the dosage. In one blister pack 10 tablets, in one whole package they can be 20 or 60, that is, 2 or 6 blisters, respectively.

The composition of the Diuver tablet includes one main component that has a diuretic effect - torasemide, and additional substances that hold the form of the drug and protect it from the aggressive internal environment of the human body:

  • magnesium stearate;
  • silicon;
  • lactose;
  • starch.

Pharmacological properties of the drug Diuver

Torasemide, which is the basis of Diuver, is a diuretic that affects the reabsorption of water, chlorine, and sodium back into the blood in the loops of the nephron (cells of the kidney tissue). It does not allow fluid to flow back into the bloodstream, as a result of which the kidneys produce and excrete more urine. Along with the flow of urine, excess salt is also excreted from the body.As a result, the pressure decreases and edema disappears.

The final effect of the drug depends on the dose taken. The peak effect of torasemide on the body falls for 2-3 hours from the moment the tablet enters the gastrointestinal tract. The effect of the main component on the body lasts from 6 to 12 hours, depending on the susceptibility of the patient.

Diuver tablets - indications for use

The drug is prescribed in order to remove excess fluid from the body in diseases such as:

  • heart failure;
  • malfunctioning of the kidneys and liver;
  • risk of cerebral edema;
  • pulmonary edema;
  • for the purpose of forced diuresis.

Also, the drug is used to normalize significantly increased blood pressure. With hypertension, Diuver is not recommended for continuous treatment. It is mainly used during and after hypertensive crises to stabilize blood pressure. But if crises often recur, the attending physician may prescribe small doses of the medication for everyday use.

Dosage and administration

The amount of the drug and the duration of the course of therapy are selected individually by the attending physician in each case.

Since the Diuver effect depends on several factors:

  • susceptibility of the patient;
  • patient age;
  • the type of pathology that led to edema;
  • the presence of somatic diseases.

The instructions for use indicate the general scheme of therapy. It consists in the single use of one Diuver tablet on an empty stomach. Drink the drug with a small amount of water.

With puffiness, initially 5-10 mg are prescribed during the day. If such a dosage does not bring the desired result, it is increased to 40 mg. The maximum allowable daily dose should not exceed 200 mg of active substance per day.

To reduce blood pressure and prevent hypertensive crises, Diuver drink 2.5 mg per day. The duration of such treatment is not limited, but you need to monitor the patient's condition in order to prevent the appearance of unwanted reactions of the body to the drug. If the first signs of Diuver poisoning begin to appear - drowsiness, nausea, constant fatigue, fatigue, carry - you must immediately stop taking the medication and replace it with one of the analogues that does not contain torasemide.

Use during Pregnancy and Breastfeeding

Using Diuver during pregnancy is strongly discouraged, since torasemide is able to penetrate the placenta into the baby's body.

Once in the body of the fetus, the substance causes disturbances in the water-electrolyte balance and a decrease in the number of platelets in the bloodstream of the child.

If there is an urgent need for a diuretic, pregnant women are allowed to prescribe the minimum dose of Diuver. During the entire course of treatment, the patient should be under stationary monitoring, and the baby's condition is also monitored daily.

Doctors try not to prescribe Diuver to women who breast-feed their children. Clinical studies of the drug in this direction have not been conducted, so it is not known for certain whether torasemide can get into milk, and with it to the baby.

Side effects of the drug Diuver

Undesirable effects from taking the drug are mainly manifested only after taking Diuver in high concentrations. If the patient follows the instructions, then the risk of side effects is minimal.

Unpleasant symptoms can occur from different organs and systems:

  • metabolism - a decrease in the number of electrolytes, alkalosis. It manifests itself as a decrease in blood pressure, headache, convulsive attacks. Drowsiness and confusion also arise;
  • heart and blood vessels - ischemia, angina pectoris, rhythm disturbances, thromboembolism, heart attack;
  • allergies - rashes, malignant erythema;
  • urinary system - urinary retention and rupture of renal tissue in patients with obstruction of the urinary duct, elevated urea and creatinine in the blood;
  • gastrointestinal tract - stomach pain, complete lack of appetite, upset stool, vomiting. Sometimes the development of inflammation of the pancreas - pancreatitis;
  • blood - a decrease in the concentration of blood cells, the blood becomes more liquid;
  • liver - an increase in specific enzymes.

Also, patients complain of deafness, tinnitus, weakness and dry mouth.

Interaction with other drugs

Torasemide actively interacts with a large number of various medicines. Prescribing it, you need to carefully collect the anamnesis and find out from the patient what other medicines he is taking.

The drug reduces the effectiveness of hypoglycemic agents, that is, drugs that reduce the concentration of glucose in the bloodstream. It also affects blood vessels, making them less sensitive to vasoconstrictors (adrenaline).

With the simultaneous use of glucocorticosteroids or those carrying Diuver, a large amount of potassium is excreted from the body. And with the appointment of torasemide along with lithium or salicylates, the toxic effect of the latter on the body is significantly increased.

Probenecid inhibits tubular secretion, as a result, the effectiveness of the diuretic decreases. Taking non-narcotic painkillers or cholestyramine also reduces the strength of Diuver's effect on the body, so the diuretic and hypotensive effect is practically not manifested.

Reception of torasemide in high dosages provokes an increase in nephro - and ototoxicity of such drugs as cephalosporins, aminoglycosides.

Drug overdose

After accidental or deliberate use of large doses of Diuver, patients develop a serious condition. It is characterized by water-electrolyte disturbances, a significant increase in diuresis (the patient almost constantly runs to the toilet), a drop in blood pressure up to the development of collapse and confusion or loss of consciousness.

If the concentration of torasemide in the blood is not very high, then patients complain of irresistible drowsiness, fatigue, the appearance of dizziness and flies. Often there is a carrying, nausea, vomiting.

There is no specific treatment for overdose, since there is no substance that could completely neutralize the effect of torasemide. In the case of poisoning with Diuver, first of all, the pill is canceled, then the patient is given symptomatic relief - the ratio of water and electrolytes is adjusted, the lost fluid and salt balance are replenished.

If after swallowing the drug less than 2 hours have passed, the patient is thoroughly washed in the stomach to remove the remaining torasemide from the body.

Analogs

Absolute analogues of Diuver are drugs whose active ingredient is also torasemide. They may differ in the type and form of release. The concentration of the basic substance may also be different.

These include:

  • Strisemide;
  • Torasemide;
  • Sutril Neo;
  • Trigrim.

There are also relative analogues.

They also have a diuretic effect, but act at a different level of urine formation:

  • Urea;
  • Veroshpiron;
  • Mannitolum.

For most Diuver analogues, the instructions for use indicate a longer list of adverse reactions and contraindications. Therefore, if there is a need to replace Diuver with another drug, you need to consult your doctor. Since the dosage and method of application may differ in the new medication.

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