A low level of activity, malnutrition, age-related changes and a genetic predisposition create an extra load on the vascular system. To prevent stagnation of blood, veins need outside help. For this, Detralex is suitable.
Material Content:
Release form, composition
The preparation includes 1000 mg of flavonoid fraction of micronized type of deep cleaning. Hesperidin (10%) entered it, and the main part is Diosmin. The medicine is created as tablets in a film shell. Detralex is packaged in two or four blisters of 15 cells each.
The Detralex series includes a suspension for oral administration. This dosage form allows you to act faster, and the active substances enter the bloodstream in larger quantities. This reduces the frequency of admission, which is suitable for busy or forgetful people.
Among the drugs with the same active substance is Detragel. It acts locally, which is important for people with liver and kidney pathologies. Especially often, the medicine is used by women and people whose type of activity exerts a load on the lower limbs. The gel has a watery consistency for faster absorption and better passage through the skin of active ingredients.
Pharmacological properties and pharmacokinetics
Detralex tablets have a stabilizing and protective effect on the veins. They are able to positively affect the walls of blood vessels and establish the movement of blood through them.As a result, the nutrition of tissues and the appearance of the limbs of the patient are improved.
Detralex series drugs help solve the problem of stagnation in the veins and prevent complications. They accelerate the outflow of lymph, which reduces swelling. The strength of the walls of blood vessels increases several times, they are less likely to get injured and better conduct blood to organs and tissues.
The action of the drug is aimed at reducing the adhesive ability of leukocytes to vascular endothelium. This prevents the destruction of the valves and walls caused by inflammatory mediators. After interacting with the body, the drug leaves it through the kidneys and gastrointestinal tract. It takes 11 hours to remove half the dose.
Indications Detralex
Detralex 1000 mg is prescribed for inhibited lymphatic circulation or venous blood flow failure of any origin (functional or organic). Especially often the vessels of the legs are affected, against the background of which cramps, pains, a feeling of heaviness and discomfort, swelling and trophic defects occur. In difficult situations, two types of drug are used: gel and tablets or suspension. This helps to quickly remove unpleasant symptoms and avoid possible complications.
With an exacerbation of hemorrhoids or at the time of its appearance, Detralex can remove pain. This significantly improves the quality of life of the patient. The tool is allowed to combine with others that have a similar effect. They are created as candles (Proctosan, Relief, Nigepan, sea buckthorn and others) or ointments for local application (Hepatrombin, Ichthyol, Bezornil).
Instructions for use
Use of the drug is possible for patients who have reached adulthood. It is prescribed as a component of complex therapy or as an independent tool. In some cases, the medicine is used immediately in two places: inside and out. This doubles the effect and allows you to solve the problem in a shorter time.
Method of administration and dosage
Instructions for use of the drug offer various options for prescribing, focusing on the disease itself, its course and the presence of complications. Detralex for varicose veins is prescribed in a dosage of 1 tablet per day during lunch. Gel treatment is carried out twice: after rising and before going to bed. Before use, it is advisable to rinse the application site with water and dry with a towel. The duration of the therapeutic course depends on the severity of the manifestations, and the need for re-treatment from the presence or absence of remission and the frequency of exacerbations.
To get rid of hemorrhoids, the medicine is swallowed every 8 hours while eating (Detralex suspension or tablets). Such a scheme is kept for 4 days, then they are reduced to 2000 mg twice (with breakfast and dinner). The general course of therapy takes 1 week.
If hemorrhoids has become chronic, the patient is prescribed Detralex at a dosage of 2000 mg in two doses for 1 week. Then leave 1 tablet or a portion of the suspension per day at lunchtime. The course of treatment reaches up to 90 days. If no improvement is observed during this time, you need to visit a proctologist to adjust the reception schedule or select a similar remedy. Usually, patients begin to feel better after 3-4 days of drug treatment.
Special instructions for use
Detralex monotherapy in acute hemorrhoids is not possible, as additional drugs are required.
To more quickly improve the patient's condition, doctors give several recommendations:
- normalize body mass index;
- eat right (be sure to include in the diet enough water and fresh vegetables);
- walk more;
- increase physical activity;
- not to be on feet for a long time;
- do not take sun baths for a long time;
- to use products from compression hosiery.
The medicine is not used to treat children, since the corresponding clinical trials have not been passed.The composition of the drug does not contain substances that could interact with alcohol. But drinking alcohol during therapy is not recommended. They increase blood flow through the vessels, which contributes to the occurrence of congestion and edema. Therefore, the effectiveness of Detralex will be reduced, and pathological symptoms will continue to increase.
Use during pregnancy and lactation
Detralex does not affect the fetus and does not contribute to the appearance of mutations. But to use it during the period of bearing a child is allowed exclusively under the supervision of a doctor and in case of emergency. During breastfeeding, the medicine is not prescribed due to the lack of data on whether it penetrates into the mother’s milk.
Empirically with the participation of female rats, the absence of toxicity in relation to the reproductive system in Detralex was proved. And the use of the drug in pregnant women has shown good results in relation to varicose veins and hemorrhoids. Therefore, its purpose is practiced in cases where diseases cause a woman significant inconvenience.
Drug Interactions with Other Drugs
Research on the interaction of Detralex with other means, scientists have not been carried out. But there is a lot of experience combining the drug with combination therapy. He showed that the tool can be combined with any names due to the lack of reaction between them.
Contraindications, side effects and overdose
The drug is prohibited to use in the presence of hyperreactivity of the body to one of its components. In all other cases, the medicine is prescribed according to indications and can be used without restrictions. Some patients may develop side effects.
These include:
- dyspeptic symptoms (vomiting, diarrhea, nausea, bloating, increased gas formation);
- weakness;
- feeling dizzy;
- migraine-like pain;
- rash;
- itchy skin;
- erythema;
- Quincke's edema (from allergies).
If one of these conditions occurs, you should visit your doctor. He will choose a remedy with a similar effect. The occurrence of an overdose of the drug is not fixed.
Analogs
People living in other states may be familiar with this drug under the names Ardium, Variton, Capiven, Venitol, Arvenum 500. These drugs are also prescribed for the presence of pathologies of the veins on the legs or other parts of the body, as well as for hemorrhoids. The treatment regimen for them completely coincides.
In Russia, you can purchase Detralex analogues:
- Ascorutin;
- Antistax
- Venolek;
- Vazoket;
- Routine;
- Venoruton;
- Troxevasin;
- Yuglaneks;
- Troxerutin;
- Phlebof.
These drugs are similar in effects to the body, but differ in composition. With similar active substances, Venarus and Venozol can be distinguished. They coincide in active components, but slightly differ in additional components, which almost does not affect the properties. Their bioavailability is slightly lower, but the schemes for getting rid of hemorrhoids and stagnation localized in the veins are completely identical. Analogs a little more often allow the occurrence of side effects, so you need to be careful and take it under the supervision of a doctor.
A popular analogue is Antistax. It contains only natural ingredients, and the basis is grape leaves. They contain flavonoids, acting as stabilizers of cell membranes. This restores the permeability of the walls of the vascular bed, which relieves swelling, improves the well-being and appearance of patients. But the result of drug therapy is not strong enough, so it is used only as a prophylaxis.
Detralex is considered the best medicine for removing the causes and consequences of venous stasis and hemorrhoids. It is allowed during the period of gestation and has virtually no contraindications. But taking it yourself is not recommended. Treatment should be prescribed and monitored by a specialist.Only then the result will be positively predictable, and have a certain dynamics.