Irregular eating, dry food are typical causes of stomach pain and digestive problems. An integrated approach is required: elimination of bad habits, dietary review, taking medications prescribed by a doctor. De-Nol, gastrotector analogues are included in the composition of therapy as a means with bactericidal activity against Helicobacter pylori.
Material Content:
Composition and active substance De-Nola
The therapeutic effect of the tablets provides bismuth trioxide. The active compound is released in the stomach from the active substance - bismuth tripotassium dicitrate. Its content in one tablet is equivalent to 120 mg of bismuth trioxide. Additionally included various excipients, for example, corn starch.
De Nol is an anti-ulcer drug popular all over the world. However, for many patients, the price of a drug manufactured in the Netherlands is not suitable. The cost of one package of tablets (56 pcs.) - 540 rubles. There are funds with a similar composition, available at more affordable prices.
Pharmacological properties and indications for admission
De-Nol and analogues in composition have practically no alternative among other drugs from the gastroprotective group. Tablets are used as an antiulcer agent. They have an astringent and anti-inflammatory effect. The drug inhibits the activity or destroys the cells of the bacterium Helicobacter pylori.
Bismuth trioxide will help to correct the situation in cases where the natural mechanism of protection of the inner wall of the stomach from hydrochloric acid, pepsin, and bile salts is disrupted.The active ingredient of the tablets combines with the substances in the mucosa, forming a thin film that for some time prevents irritation and tissue damage. Under this additional layer, natural scarring of erosion and ulcers occurs.
Thanks to the drug, the acute manifestations of stomach diseases associated with Helicobacter pylori infection are reduced in a short time.
De-Nol is prescribed for the following diseases and conditions:
- chronic antral gastritis (inflammation associated with Helicobacter pylori);
- gastroduodenitis in the acute stage;
- irritable bowel syndrome;
- exacerbation of peptic ulcer;
- non-ulcer dyspepsia.
Peptic ulcer in medicine is called damage to the stomach and upper part of the duodenum under the influence of aggressive components of gastric juice. Helicobacter pylori infection reduces natural protective abilities and destroys the gastric mucosa. And also the bacterium Helicobacter pylori is one of the causes of gastritis.
The infection is contagious, transmitted with a kiss, while using one fork, spoon, cup. It is necessary to suppress the activity of pathogenic bacteria, then the treatment of erosion and ulcers caused by the action of aggressive contents will be more successful.
De Nol works best in combination with proton pump inhibitors and antibacterial agents.
The medicine is practically not absorbed from the intestine. A small amount of bismuth compound penetrates the plasma and is excreted by the kidneys. The drug does not accumulate in the body, ultimately it is completely excreted.
Bismuth compounds are hardly absorbed in the digestive tract, but De-Nol is not used to treat pregnant women. The drug can adversely affect the developing fetus. During breastfeeding, you should also refuse to use the medicine.
Instructions for the use of antiulcer drug
The method of administration and dose depend on the disease, its stage, severity, age of the patient. Adults and adolescents over 12 years of age are recommended to take 1 tablet 4 times a day and even at night. Another treatment regimen is also possible - 2 tablets twice a day.
Children's dosages in the instructions for use are indicated taking into account age and body weight:
- from 8 to 12 years - 1 tablet 2 times a day;
- from 4 to 8 years - the dose is calculated according to the formula 8 mg of medicine * kg weight / day, divided into 2 doses.
Take De Nol 30 minutes before a meal. The course of treatment with a bismuth preparation usually lasts 1-2 months. After the end of the intake, it is not recommended to drink medicines with the same active ingredient in the composition for 2 months.
List of cheap Russian analogues
Anti-ulcer drugs, which include bismuth compounds, are released only in tablet form. Analogs are cheaper to produce in Russia. Domestic medicines contain the same active ingredient - bismuth tripotassium dicitrate. Its concentration in one pill in terms of bismuth trioxide is 120 mg.
Indications and methods of use of the original remedy and generics completely coincide.
Domestic analogues of De Nol by active substance and release form:
- Novobismol.
- Vitridinol
- Escape.
The cost of packing Novobismol tablets (56 pcs.) Is about 370 rubles. Vitridinol can be purchased at a price of 350 rubles. The cost of Escape tablets (40 pcs.) - from 270 to 360 rubles.
Ulkavis is a structural analogue of De Nol, a medicine for imported stomach ulcers. The cost of packaging (28 pcs.) - 185-200 rubles.
Medicines similar in pharmacological properties
Among the substitutes for De-Nol there is a combination drug. These are Vicair tablets, which contain bismuth subnitrate, powders from rhizomes of calamus and buckthorn bark, sodium and magnesium salts. The tool has moderate antiulcer, astringent, antacid and antispasmodic properties. Vicair better helps with hyperacid gastritis. The cost of the drug is 73 rubles.
Venter - a drug with another gastroprotector in the composition. The substance Sucralfate has an adsorbing, enveloping, antacid, antiulcer effect. Take a remedy for gastritis and ulcers. The cost of packing tablets (50 pcs.) - 300 rubles.
Gastroprotectors with bismuth tripotassium dicitrate, other active ingredients are rarely used for monotherapy. When infected with Helicobacter, antral gastritis, peptic ulcer, treatment with several drugs is preferable.
De-Nol and analogues are prescribed to protect the gastric mucosa from damage, enhance the effect of antibiotic treatment. Gastroprotectors help to cope with painful symptoms with exacerbation of gastritis and ulcers, reduce the devastating effects of diseases.
