Effective analogues of Bisoprolol in Russia are represented by several dozen positions. They differ in the formula (more often - auxiliary components), dosage, manufacturer and pricing policy. Funds are sold by prescription and are taken in accordance with the recommendations of a doctor.
Material Content:
Composition (active substance) of Bisoprolol
Bisoprolol is included in the clinical and pharmacological group of selective β1-adrenergic blocking agents that reduce cardiac activity, myocardial oxygen demand, and blood renin level. The active substance is bisoprolol fumarate, a soluble crystalline white powder. The peak of its action is observed 2-4 hours after taking the pill and persists for a day.
The tablets contain from 2.5 to 10 mg of the active ingredient, which is the basis of many drugs of similar action both original (patented, having passed a multi-stage system of clinical trials) and generics (cheaper medicinal products with other auxiliary components in the formula that are marketed after the expiration of the patent for the original). The substance is metabolized in the liver and excreted by the kidneys.
Indications for use of tablets
Bisoprolol is used for high blood pressure, for symptomatic treatment during autonomic crises and panic attacks, for rehabilitation after heart attacks, as well as for problems with the cardiovascular system of a chronic or stable nature:
- angina pectoris;
- arrhythmias;
- heart failure.
Moreover, according to statistics, for every fifth patient, the drug does not have an effect in view of the low ischemic threshold, coronary atherosclerosis, or prolonged smoking.
Russian analogues of antihypertensive drug
The original drug is produced by the German company Merck called Concor (the price is up to 987 rubles in Moscow pharmacies). Medicines presented on the domestic pharmaceutical market are its generics (Bisomor, Corbis, Coronal, Biol and others). The main Russian substitutes for Bisoprolol are Aritel, Niperten, Perindopril.
Almost an absolute analogue is Aritel tablets. The peak action of this beta-adrenergic blocking drug is achieved on 13-14 days from the start of therapy. Indications for use and severe restrictions are identical to the main drug. Before use, you need to read the instructions for use.
Common side effects:
- hearing impairment;
- decreased natural tear production;
- partial hair loss;
- potency disorders (rarely);
- upset stool, constipation;
- muscle cramps and others.
These reactions are observed mainly with hypersensitivity to the components (extremely rare phenomenon) and pass within the first 24-48 hours without additional treatment. Their longer manifestation is an occasion for consultation with a doctor and complete discontinuation of the drug.
The price in pharmacies in Russia ranges from 37 to 900 rubles, depending on the manufacturer and dosage.
Important! During pregnancy, it is not recommended, as it can adversely affect the fetal development. There are no data on excretion with breast milk.
A good tool is Niperten based on bisoprolol fumarate (2.5, 5 or 10 mg of an active drug compound in 1 tablet).
However, among the adverse reactions caused by taking the drug, there are:
- decreased secretion of lacrimal fluid;
- a feeling of cold and tingling in the lower extremities;
- fatigue;
- intensification of psoriasis-like rashes and bronchial obstruction (rare).
Use during pregnancy is undesirable and should be carried out under the strict supervision of a physician. It is advisable to stop taking the medicine at least 72 hours before giving birth because of the likelihood of respiratory depression in the newborn.
The average cost is 226 rubles.
Please note! Niperten is prohibited for use in diabetes mellitus, pulmonary edema, collapse.
Another perindopril analogue is pressure tablets based on perindopril erbumin (4 mg).
Auxiliary components in the formula:
- lactose;
- magnesium stearate;
- cellulose.
It also has an extensive list of contraindications, including:
- periods of gestation and lactation;
- children under 18 years old;
- scleroderma;
- renal artery stenosis;
- angioedema (hereditary or idiopathic).
The reception may be accompanied by the appearance of a dry cough, breathing problems, weakness, dry mouth and other undesirable consequences.
The price in pharmacies is 84-352 rubles, depending on the manufacturer.
Imported Drug Substitutes
Imported analogs of Bisoprolol in tablets differ from domestic ones in more thorough systems of research and testing conducted before entering the pharmaceutical market.
As well as cheap antihypertensive drugs, they have a number of strict intake restrictions.
- Bisoprolol-Ratiopharm (Germany) is prohibited in case of cardiogenic shock, sinus node weakness, symptomatic bradycardia and hypotension, bronchial asthma and bronchospasm. Its use during pregnancy is fraught with premature birth, fetal freezing or growth retardation. A doctor is urgently informed of an overdose, treatment with the drug is stopped. The price is 170 rubles.
- Bidop (Ireland / Hungary) and Bisogamma (Germany) contain the active component in the form of hemifumarate. Bisogamma is taken strictly in accordance with the prescribed treatment regimen, otherwise the medicine may cause a "withdrawal syndrome."Bidop is sold at 105-145 rubles for 14 tablets, Bisogamma - at 136-192 rubles.
- Azoprol Retard (India) based on metoprolol succinate 12.5 mg is used up to 50-100 mg / day, but it is not recommended to increase the initial dose over 25 mg. Adverse reactions are manifested in impaired sleep, breathing, heart rhythm, allergic rashes. You can buy for 140-180 rubles.
Modern generics without side effects
By the number of generics, the Russian pharmaceutical market is second only to China and India, therefore, it is not easy for a person without an appropriate education to choose an effective product with the desired active substance in the composition. In this case, almost no generic is completely safe for health and often causes multiple side effects. A qualitative analogue of Bisoprolol is Biprol of Russian production with the same substance in the composition. It has antianginal, antihypertensive and antiarrhythmic effects. The duration of therapy is determined by the doctor. For elderly patients, as well as with liver or kidney dysfunction, the dosage is not adjusted.
Note! Bisoprolol analogues can be prescribed to women in the I-III trimesters of pregnancy only if the benefits for the mother prevail over the risk of complications in the fetus.
Given the extensive list of possible undesirable effects on the part of all body systems, medications based on bisoprolol are selected by the specialist. In the event of any complications, the administration of tablets is suspended and the medication is replaced with a similar action.
