Atenolol Nycomed is a classic medicine that reduces cardiac output and also regulates the heart rate, which allows you to normalize your blood pressure. It positively affects the activity of the cardiac and vascular systems in the presence of acute or chronic pathologies.

Description of the release form and composition

The medicine is a white film-coated tablet. Each has a dividing line and the letters "AB55" ("AB"). They are sold in a plastic container that holds 30 tablets.

The list of components of the medicine includes:

  • the main drug atenolol "AB55" - 50 mg, "AB57" - 100 mg;
  • sodium lauryl sulfates;
  • magnesium sulfate stearates;
  • magnesium sulfate carbonates;
  • titanium dioxide.

Pharmacological action and pharmacokinetics

The medicine is a selective beta1-blocker. The effect of the drug on the body is manifested in the blocking of impulses of the nervous system. Due to which, the strength of heart rate decreases. And also it has a hypotensive effect - lowers blood pressure. Due to this, the violation of the rhythm of the heartbeat and antianginal effect are eliminated. And also the drug removes the symptoms of myocardial ischemia.

In the first 24 hours after ingestion of Atenolol Nycomed, an increase in the peripheral resistance of blood capillaries is manifested due to a decrease in blood flow. In the next 2-3 days, the severity of this effect is steadily decreasing.The antihypertensive effect is seen in a decrease in heart rate per minute, as well as a decrease in blood pressure.

The effect of the drug lasts on average during the day, with prolonged use (10-14 days), the indicators stabilize.

From the digestive tract, the drug is partially absorbed - by 45-60%, bioavailability is 40-50%, and the greatest concentration in the circulatory system occurs within 2-5 hours. Poor permeability through the blood-brain barrier, in small volumes is able to pass into breast milk.

In the liver, it is almost not able to metabolize. The time of elimination from the circulatory system is about 8 hours. In patients over the age of 50, up to 10 hours. Fully excretion is performed due to the kidneys in the amount of 80-99% in its original form.

With renal failure, the time of removal from the body increases. In addition, you need to reduce the dosage of the drug, which subsequently leaves the body during hemodialysis.

Indications Atenolol Nycomed

Due to the fact that Atenolol primarily has a hypotensive effect on the body, the indications for use are as follows:

  • disturbances in the rhythm of the heart;
  • pathological increase in blood pressure;
  • myocardial circulatory disorders;
  • neurocircular dystonia of the heart;
  • the presence of arterial hypertension;
  • during the prevention of angina attacks.

Due to the positive effect on the central nervous system, the use of the drug gives the best results for the treatment of essential tremor, migraines, thyrotoxicosis. And also in complex use with essential drugs, it helps to reduce the somatic manifestation of anxiety and panic.

Instructions for use and dosage

The tool is taken before meals, in general, and washed down with a large amount of liquid. The recommended amount of medication is not more than 1 tablet per day.

The following dosage regimen is shown:

  • with hypertension - 50 mg for 7-14 days. The dosage is increased to 100 mg as indicated by a specialist if a sufficient hypotensive effect does not occur;
  • with angina pectoris, Atenolol 50 mg tablets for 7 days. If the treatment does not provide the desired therapeutic effect, according to the doctor’s testimony, the dose is increased to 150-200 mg per day.

If the patient is on hemodialysis, then the volume of his daily dose is 25 or 50 mg. The drug is taken immediately after the procedure and under the supervision of physicians, since a sharp decrease in blood pressure is quite possible for the patient.

During pregnancy and lactation

Due to the ability of the drug to penetrate the placenta, it is prohibited for pregnant women in the I, II trimester and during planning. Taking the medicine can provoke such abnormalities as fetal pathologies, delays in the rates of development and growth, heart failure, late delivery and even death of the embryo.

In the absence of other effective treatment options, the use of Atenolol Nycomed is carried out strictly under the supervision of physicians.

And only in situations where the intended benefits of treatment are much more potential harm to the child.

It is impossible to combine the intake of the drug and feeding due to the fact that the medicine will be present in the composition of breast milk.

Drug compatibility with alcohol

There are no such medicines, the use of which with alcoholic drinks would not entail negative consequences. The combination of Atenolol with ethanol leads to the fact that the inhibitory effect of the drug on the central nervous system is enhanced, and the exposure period also increases. During treatment, it is best to completely eliminate the likelihood of taking alcohol. At a minimum, you need to refrain from them for 12 hours before and after taking the drug. Otherwise, there is a risk of a sharp drop in blood pressure. There will be severe weakness and nausea, fainting.

Drug interactions

Instructions for use provide information about a limited number of medicines with which this drug interacts:

  • verapamil, diltiazem - increased action of both drugs;
  • insulin - increased effect of Atenolol;
  • nitrates, antihypertensive agents - an increase in the hypotensive effect;
  • nifedipine - a high probability of a sharp decrease in blood pressure;
  • estrogen, NSAIDs - a decrease in the antihypertensive effect of the drug;
  • amiodarone - increased risk of atrial ventricular conduction disturbance, as well as the appearance of bradycardia;
  • xanthine, ergotamine and their derivatives - a decrease in the positive effect of the drug;
  • lidocaine - a decrease in the rate of removal of the drug from the body, an increase in the effect of toxins;
  • phenothiazine and its derivatives - an increase in the concentration of both drugs in the circulatory system;
  • reserpine, methyldop, clonidine - the risk of severe bradycardia;
  • aminophylline, theophylline - the probability of lowering the therapeutic effect of both drugs;
  • cimetidine - a slowdown in metabolism due to increased concentration in the circulatory system;
  • sedatives, antipsychotics, sleeping pills, sedatives - CNS depression;
  • coumarin - an increase in the period of its exposure;
  • allergen extracts for skin tests - increased risks of a burdened systematic allergy or anaphylactic shock.

The break between the use of any of the medicines after Atenolol should be at least 14 days.

Contraindications, side effects, overdose

Doctors prescribe medicine with caution in cases of presence of:

  • a history of allergies;
  • depressive states;
  • deviations in the endocrine system;
  • hypoglycemia;
  • diseases of the respiratory system;
  • during pregnancy;
  • over the age of 50.

Contraindications for use are justified if:

  • cardiogenic shock and ischemia;
  • sinus node attenuation syndrome;
  • sinoauricular and atrioventricular block;
  • acute or chronic diseases of the heart system;
  • pronounced bradycardia;
  • cardiomegaly;
  • atherosclerosis;
  • hypertension or hypotension;
  • dystonia;
  • Prinzmetal angina pectoris;
  • breastfeeding period;
  • passing hemodialysis.

In case side effects occur, you must immediately stop taking the medicine.

The most common include:

  • tachycardia and shortness of breath, shortness of breath;
  • a sharp decrease in blood pressure;
  • swelling of the ankles, feet;
  • impaired coordination, concentration of attention;
  • migraine;
  • nightmares, hallucinations;
  • general weakness of the body, excessive fatigue;
  • periodic memory lapses;
  • drowsiness or insomnia;
  • a change in the perception of taste buds;
  • drying out of the oral mucosa;
  • violation of the gastric tract.
  • swelling of the mucous membranes of the nasopharynx;
  • decreased libido;
  • hyperglycemia or hypoglycemia;
  • swelling of the mammary glands;
  • allergic rash, urticaria, dermatitis;
  • pain in the heart, back muscles and joints;
  • fetal fading;
  • pain in the spine.

Symptoms of exceeding the allowable dosage of the medication are sharp shortness of breath, bronchospasm, fainting and dizziness, convulsions of the extremities, loss of consciousness.

In such a situation, you should immediately call a doctor and provide first aid to the victim. Rinse the gastrointestinal tract and give an absorbent and sympatholytic drug.

Analogs Atenolol Nycomed

To replace the drug, drugs with a similar active ingredient are suitable.

The most popular are such analogues of Atenolol Nycomed:

  • Atenobene. Suitable in the treatment of angina pectoris;
  • "Atenova." Antianginal and antihypertensive drug;
  • Atenol. It has antiarrhythmic effects on the body;
  • Tenolol. The drug is in tablets for arrhythmia.
  • "Bisoprolol." Allowed during pregnancy.

Atenolol Nycomed is one of the most popular and inexpensive medicines for the treatment and prevention of diseases of the cardiovascular system. However, due to the large number of contraindications and side effects, it should be used strictly after consultation with a specialist. It is released exclusively by prescription.

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