Arcoxia 90 - a drug that has anti-inflammatory, analgesic, antipyretic properties, belongs to the 2nd generation inhibitors. Most often, a medication is prescribed to relieve the pronounced symptoms of rheumatism, arthritis, arthrosis.

Description of the release form and composition

Instructions for use states that Arkoxia is only available in apple-shaped, biconvex tablets. Available in 60 mg, 90 mg, 120 mg.

The medication consists of an active substance, etoricoxib, in addition to which it is enriched with the following auxiliary components:

  • calcium
  • sodium;
  • dye;
  • hypromellose;
  • lactose;
  • titanium dioxide.

The tablets are coated with an enteric coating on top, which allows the active substance to reach the small intestine unchanged without being subjected to the aggressive effects of hydrochloric acid.

Pharmacological action, pharmacodynamics and pharmacokinetics

During therapy with the drug, the synthesis of COX, cyclooxygenases, prostaglandins, responsible for the occurrence of pain, its spread throughout the body, is selectively delayed. Thus, the inflammatory focus, fever, pain syndrome with articular, intraarticular pathologies burdened by a degenerative, dystrophic process is removed.

In the course of studies, it was found that with the use of Arkoxia 60 mg, the symptoms of osteoarthritis are relieved, the patient's condition improves. As a result of treatment with Arkoxia 90 mg, pain and inflammation are eliminated, joint mobility improves with rheumatoid arthritis, spondylitis. Improvement is observed the next day and persists for 12 days. To alleviate the condition of the patient with gout, a dosage of 120 mg is necessary.

An hour after penetration into the body, the maximum concentration of the active component is achieved. The use of tablets during meals does not adversely affect their absorption. The drug is actively absorbed into the bloodstream, the metabolic process occurs in the liver. Most of the active substance is excreted through the urinary system, a smaller one with feces. The half-life of Arcoxia is 90 - 22 hours, and it does not change depending on the patient's age and gender.

What helps Arcoxia 90 mg

Arcoxia 90 mg tablets are used as symptomatic therapy in the following conditions:

  • osteoarthrosis;
  • rheumatoid arthritis;
  • ankylosing spondylitis;
  • acute, chronic myalgia;
  • pain caused by the inflammatory process, gouty arthritis.

In addition, this pain medication is often used for the short-term elimination of symptoms after previous dental procedures.

On a note. Taking Arcoxia 90 does not mean canceling other drug groups prescribed by your doctor.

Instructions for use and dosage of tablets

Arcoxia 90 is taken without regard to meals. However, if it becomes necessary to relieve acute symptoms, it is better to drink tablets before meals. Since a faster onset of action of the drug is noted.

In order to prevent complications on the cardiovascular system, it is forbidden to exceed the recommended dosage and duration of treatment. Therapy of Arkoxia 90 is carried out with the minimum acceptable doses. During treatment, it is necessary to assess the patient's condition, its symptoms, to adjust the dosage.

This is especially true for people with osteoarthritis:

  • with osteoarthritis, 30 mg are prescribed once a day. If the desired result is not observed for a long time, then the question of increasing the dose to 60 mg is considered. In isolated cases, it is possible to use 90 mg once a day;
  • with rheumatoid arthritis, it is recommended to drink 60 mg once a day. If the desired result is not achieved for a long time, then the possibility of increasing the dosage to 90 mg is considered. After stabilization of the patient's condition, the dose is reduced to 60 mg once a day;
  • with ankylosing spondylitis, it is prescribed to drink 60 mg per day. If the result is not achieved, the possibility of increasing the dosage to 90 mg is considered. After improvement of the patient's condition, a volume is reduced to 60 mg once a day;
  • in acute pain, Arcoxia 90 tablets are prescribed only to relieve symptoms;
  • with acute rheumatoid arthritis, 90 mg is prescribed once a day. If the symptoms do not decrease, then the dose increases to 120 mg;
  • in the postoperative period, they are prescribed to drink 90 mg once a day for no more than 3 days.

The duration of the drug is discussed individually with the attending physician. If the symptomatology is not relieved during treatment with Arkoxia 90, it is necessary to reconsider the medication.

During pregnancy and lactation

Arkoxia is not recommended for pregnant women. If pregnancy occurs during the therapy with these pills, then it is necessary to cancel it in order to prevent the negative effect of the active substance on the fetus. The drug used in the last trimester can suppress the contractility of the uterus and close the arterial duct ahead of time.It is forbidden to treat medication to women who are in the lactation period. If this need arises, then the baby should be transferred to artificial feeding.

Alcohol compatibility

Arcoxia 90 is forbidden to be consumed simultaneously with any alcoholic beverages. As the toxic load on the liver cells increases. Alcohol leads to an increase in the inflammatory focus, thereby worsening the therapeutic effect of the drug.

Drug interaction

Arcoxia 90 when interacting with certain drugs negatively affects the body:

  • with cyclosporins, the toxic load on the kidneys increases;
  • with methotrexates, the possibility of developing more vivid side effects of antitumor drugs increases;
  • with rifampicins, the absorption of the non-steroid worsens;
  • with antihypertensive agents, the effectiveness of Arcoxia is weakened;
  • with antacids, side effects from the digestive tract increase;
  • with hormonal contraceptives, the risk of thrombosis increases.

In addition, parallel use of Arkoxia with other NSAIDs is prohibited.

Contraindications, side effects and overdose

Arcoxia 90 is contraindicated in the following conditions:

  • renal failure;
  • ulcerative colitis;
  • gastric bleeding;
  • hyperkalemia
  • gastrointestinal ulcer;
  • ischemia;
  • heart failure;
  • recurrent sinus polyposis;
  • sensitivity to the active component;
  • in children under 16 years old;
  • after undergoing coronary bypass surgery;
  • during the bearing of the child;
  • during lactation.

With caution, the drug should be taken when the stomach is infected with Helicobacter bacterium, diabetes mellitus, in old age. A relative contraindication to taking this medication is the prolonged use of other nonsteroids, the abuse of alcohol.

Against the background of taking Arcoxia 90, side effects may develop in the form of the following symptoms:

  • anxiety
  • Dizziness
  • drowsiness
  • apathy;
  • low attention;
  • confusion of consciousness;
  • impaired taste;
  • conjunctivitis;
  • heart palpitations;
  • increase in blood pressure;
  • impaired blood circulation;
  • anemia
  • thrombosis;
  • coughing
  • shortness of breath
  • bronchospasm;
  • nosebleeds;
  • nausea
  • vomiting
  • loss of appetite;
  • constipation
  • gastrointestinal ulcers;
  • increased gas formation;
  • pain in the abdomen;
  • seizures
  • skin rashes;
  • urticaria;
  • itchy skin;
  • anaphylactic shock.

If side effects occur, it is necessary to consult a doctor about dose adjustment of the drug, its replacement.

Analogues of anesthetic

Due to the high price category, a large number of side effects, the question often arises about the analogues of Arcoxia.

Usually, the following drugs are replaced:

  • Diclofenac, which effectively relieves fever, has an anti-inflammatory, analgesic effect;
  • Nimesulide, which is a non-steroidal anti-inflammatory drug that is effective against articular pathologies. Relieves toothache, headache;
  • Dilax. The drug is used to treat diseases of the musculoskeletal system, relieves fever;
  • Arthrofoone can be used not only for the treatment of articular pathologies, but also to prevent them;
  • Arthrovit. The drug is made from natural ingredients. Against the background of its intake, the condition of the joints improves in the chronic course of the disease;
  • Celecoxib is used to relieve the inflammatory process, fever, pain;
  • Ibuprofen used to treat joints, relieve pain, inflammation, fever, and fever.

Only a doctor should deal with the selection of analogues, depending on the type of pathology, the condition of the patient, his age, the presence of concomitant diseases, the characteristics of the drug, contraindications, and the number of side effects.

Arcoxia 90 is a modern drug used to treat joint diseases, allows you to relieve inflammation, pain.