Antigrippin is a Dutch-made medication. It eliminates the characteristic symptoms of colds and infectious diseases. This is a fairly effective drug that can be used to treat children.
Material Content:
- 1 Release form, composition and packaging
- 2 Pharmacological action, pharmacodynamics and pharmacokinetics
- 3 What helps Antigrippin
- 4 Instruction for use of effervescent tablets for adults and children
- 5 During pregnancy and breastfeeding
- 6 Drug interaction
- 7 Antigrippin Compatibility with Alcohol
- 8 Analogues of the drug
Release form, composition and packaging
Due to its complex composition, Antigrippin has a complex effect on the body.
A medication consists of the following active components:
- ascorbic acid;
- paracetamol;
- chlorphenamine maleate.
The following types of medication are presented:
- adult round effervescent tablets with beveled edges, with a citrus smell. Available in 10 pieces. in a plastic tube;
- fruit effervescent tablets for children. Packed in 10 pieces. into a plastic tube;
- Antigrippin powder. The drug is white. Has a camomile, honey, lemon aroma. One sachet contains 5 g of the drug;
- Antigrippin ANVI. A drug produced in green capsules from gelatin;
- Antigrippin Maximum is represented by blue capsules from gelatin.
Powdered Antigrippin contains active ingredients in the following dosage:
- paracetamol - 500 mg;
- ascorbic acid –200 mg;
- chlorphenamine maleate - 20 mg.
In addition to the main components, the powder consists of the following substances that do not have an active effect on the body:
- sucrose;
- citric acid;
- aspartame;
- flavorings;
- povidone;
- sodium bicarbonate.
Antigrippin in the form of effervescent tablets for adults has the following dosage of active ingredients:
- paracetamol - 500 mg;
- ascorbic acid - 200 mg;
- chlorphenamine maleate - 20 mg.
Along with the active ingredients, an adult antigrippin consists of the following components that do not have a therapeutic effect on the body:
- sorbitol;
- citric acid;
- sodium bicarbonate;
- flavorings;
- macrogol.
Antigrippin for children consists of the following components:
- paracetamol - 250 mg;
- ascorbic acid - 50 mg;
- chlorphenamine maleate - 3 mg.
Effervescent tablets consist of the following ingredients that do not have an active effect on the body:
- citric acid;
- sorbitol;
- flavorings;
- macrogol;
- silica;
- sodium carbonate.
Pharmacological action, pharmacodynamics and pharmacokinetics
Antigrippin is distinguished by the complexity of the composition. It contains a number of active components that effectively fight the painful state of an infectious nature, inflammation.
The drug has the following types of action:
- antipyretic;
- analgesic;
- anti-allergic;
- anti-inflammatory;
- regulating carbohydrate metabolism;
- increasing overall resistance to infections.
Thanks to this, Antigrippin reduces fever, eliminates pain, nasal swelling, sneezing, reduces inflammation, and increases the activity of immunity.
After use, the drug begins an active effect, which lasts 5 hours. Then the symptoms return or appear weaker. Antigrippin leaves the body through the urinary system.
What helps Antigrippin
Antigrippin is usually recommended to be used to eliminate unpleasant symptoms caused by viruses, the inflammatory process, in order to alleviate the general condition of the patient.
The greatest effect can be obtained if treatment is started at the first signs of the disease, such as:
- fever;
- heat;
- joint pain;
- sinus congestion;
- neuralgia;
- arthralgia.
Pediatricians recommend the use of children's Antigrippin to eliminate the unpleasant symptoms caused by teething. When a convulsive syndrome occurs in a child against a background of high temperature, the medication is used to prevent seizures as a reaction to high temperature.
Instruction for use of effervescent tablets for adults and children
Before taking Antigrippin, it is recommended to dilute it in 250 g of warm water, but not boiling water. It is desirable that the temperature of the liquid is about 50 degrees. A medication is allowed to drink regardless of food. For better tolerance, children are best given after meals.
Important! The resulting solution of Antigrippin must be taken immediately after manufacture. The medicine is not subject to storage.
At least 4 hours should elapse between doses of antigrippin in adult patients. For children, the interval increases to 6 hours. If the patient has renal pathologies, then it is necessary to increase the interval between the use of effervescent tablets to 8 hours.
Pediatricians recommend the use of antigrippin in children as follows:
- Until the age of five, it is recommended to drink 0.5 tablets. twice a day;
- up to the age of ten give 1 table. twice a day;
- over the age of ten is allowed to give 1 table. Thrice a day.
Without consulting a pediatrician, it is allowed to use a medication for 3 days to relieve symptoms. To achieve a decrease in temperature, relieve pain, Antigrippin is given for 5 days. If, after the indicated time has not elapsed, improvement does not occur, then a visit to the doctor is necessary to clarify the diagnosis and change the medicine.
Important! Antigrippin in the form of children's effervescent tablets is given only after reaching the age of three.
An adult dosage of Antigrippin is given upon reaching 15 years of age. To achieve the desired result, 1 effervescent table. diluted in 250 mg of water. It is allowed to drink 3 tablets per day. with a four-hour break. For debilitated, elderly people, people with pathologies of the liver, kidneys, the interval must be increased to 8 hours.To relieve colds, they take the medication for 3 days, to eliminate the pain - 5 days.
During pregnancy and breastfeeding
Antigrippin easily penetrates the placental barrier, enters with mother’s milk, and damages the undeveloped child’s body. As a result, tablets are prohibited for use by pregnant and lactating women. Otherwise, there is a risk of fetal lung disease. There were cases of inhibition of childbirth.
In a nursing infant, subject to taking the drug by a nursing woman, bleeding may occur as a result of impaired platelet function.
Drug interaction
Due to the fact that Antigrippin is a rather complex combined medication, it is characterized by a difficult interaction with other drugs:
- with antidepressants - provides for severe intoxication of the body;
- with ethanol - causes acute pancreatitis;
- with Diflunisal - increases one and a half times the content in the blood of Antigrippin;
- with barbiturates - reduces the amount of antigrippin in the blood;
- with cimetidine - disrupts the functioning of the liver;
- with sleeping pills - increases their activity;
- with antipsychotic medications - the risk of side effects increases;
- with hormonal agents - glaucoma may develop;
- with tetracyclines - their amount in the blood increases;
- with sulfonamides - the balance of free calcium is disturbed;
- with iron-containing drugs - there is an increase in the period of their excretion;
- with anticoagulants - leads to an increase in their content in the blood;
- with amphetamine - the calcium content decreases;
- with oral contraceptives - their effectiveness is reduced.
Antigrippin Compatibility with Alcohol
The simultaneous administration of Antigrippin with alcohol-containing drinks has a negative effect on liver cells as a result of the accumulation of toxins. Effervescent tablets are not prescribed for alcohol abusers.
Contraindications, side effects and overdose.
Antigrippin in any form is contraindicated in the presence of:
- pregnancy
- gastrointestinal erosion;
- glaucoma
- renal disease;
- serious liver disease;
- alcoholism;
- prostatitis
- congenital metabolic disorders of amino acids;
- hyperbilirubinemia;
- glucose deficiency;
- progressive oncology;
- hyperoxalaturia.
Against the background of taking Antigrippin, cases of distortion of laboratory results are known. There is no way to estimate the exact amount of sugar in the blood, bilirubin, urea. Components can cause accelerated growth of malignant tumor formation, the process of metastasis.
Antigrippin provokes a lot of side effects, which manifest themselves in the form of:
- fatigue;
- nausea
- pain in the lower abdomen;
- hypervitaminosis;
- itching
- rashes on the skin;
- anemia
- Quincke's edema;
- urticaria;
- increased dryness of the mucous membranes;
- drowsiness
- Dizziness
- headache;
- tachycardia;
- increase in blood pressure;
- tinnitus;
- short-term hearing loss;
- diarrhea
- discolored urine.
Cases of overdose are manifested by a large number of negative reactions from the body, and their high intensity.
Analogues of the drug
Usually, as an analogue of Antigrippin, according to the active ingredient, they suggest taking AntiFlu Kids.
In the form of substitutes for pharmacological action, the following medications are allowed:
- Acetaminophen;
- Kalpola;
- Teraflu;
- Fervex;
- Cefecone;
- Efferalgan;
- Panadola
- FluFlu;
- Pentalgin;
- Mexalena.
Replacement of Antigrippin with analogues can be carried out exclusively after consulting a doctor. Since medications can differ in the nature of contraindications.
Antigrippin successfully fights the symptoms of flu, colds. But this drug is taken in combination with the main therapy. Since it is not capable of exerting anti-inflammatory, antiviral effects.