The antibiotic Amoxicillin belongs to the group of penicillins and is highly active in relation to various pathogens. Semi-synthetic component according to the principle of action and properties, it has much in common with ampicillin, but is more effective, is better absorbed by the body.

Forms of release, composition

The drug is available in the following forms:

  • ordinary capsules;
  • dry powder, which is used for injection;
  • solution for internal use;
  • suspension.

The most popular are Amoxicillin tablets. The medicines are coated, so the entire dose of the active component goes directly to the digestive tract, from where it spreads with blood throughout the body. Tablets with an active substance content of 500 mg or 1 g are available for sale. Prescription drug is dispensed from pharmacies.

The active component of the drug is amoxicillin trihydrate. A set of auxiliary components depends on the form of release. For example, tablets contain cellulose, magnesium stearate, talc, titanium dioxide, etc.

Pharmacological properties and indications for use

The antibiotic "Amoxicillin" acts immediately in several directions, has a wide scope, has an antimicrobial, bactericidal effect. The substance is resistant to acidic environments. The component penetrates the cell structure of the pathogenic bacteria, stops the growth and development of microbes, makes them unable to multiply.

The drug is highly active against microorganisms that provoke the development of salmonellosis, gonorrhea, meningitis, streptococci, staphylococci.

Amoxicillin is useless in the fight against bacteria that can produce penicillinase.

The effect of the use of the antibiotic occurs within 30 minutes after administration, lasts up to 8 hours.

The drug is indicated for the same diseases and disorders:

  • bronchitis, otitis media, sinusitis;
  • gonorrhea, cystitis;
  • typhoid fever, dysentery;
  • dermatoses of bacterial origin;
  • sepsis, meningitis, etc .;

"Amoxicillin" is advisable to use for infections of the ENT organs, gastrointestinal tract infections, skin, urogenital system. The drug is ineffective in the fight against diseases of viral etiology.

Age restrictions on admission

The advantage of this medication is that it acts gently on the body, but quickly and effectively destroys pathogenic bacteria. With this tool, you can significantly improve the patient's condition on the first day of therapy.

Amoxicillin will help shorten your recovery period. There are no age restrictions on the use of the medication - it is prescribed for both adults and children. When determining the dose, the age and weight of the patient, the degree of development of the disease, the state of health of the patient are taken into account.

Instructions for use Amoxicillin for children and adults

You can not start taking the drug without first consulting a specialist, especially if an antibiotic is used to treat a child. Be sure to follow the doctor's instructions and adhere to his recommendations. The only way to achieve a quick, expressive therapeutic effect.

Methods of administration and dosage regimen

Amoxicillin 500 mg tablets are taken orally, washed down with water, regardless of the meal regimen. For children who cannot swallow this form of medication, the medications are pulverized and diluted with liquid.

Standard daily dosages for infectious diseases:

  • 750 mg - 3 g - adults;
  • 25 - 50 mg per 1 kg of mass - "Amoxicillin" for children under the age of 10 years or weighing up to 40 kg;
  • 500 mg - adults with severe kidney disease;
  • 15 mg / kg - children diagnosed with renal failure.

If the drug is used to prevent the development of endocarditis, it is administered in a dose of 3 g once 1 hour before surgery and then another 3 g 6 hours after, if necessary.

Dose adjustment in the treatment of elderly patients is not required. Amoxicillin therapy can be short and routine. In the first case, the duration of the course is 2 applications of 3 g each with an interval of 10 to 12 hours. In the second - 2 to 3 days. In infectious diseases caused by the activity of streptococcus, it is advisable to continue therapy for 10 days until the pathogen is completely eradicated.

Special instructions for taking the antibiotic

Before prescribing "Amoxicillin", you must make sure that the patient does not have hypersensitivity to cephalosporins and penicillins. Against the background of the use of the drug, anaphylactic reactions can occur that pose a danger to the life and health of the patient.

If the patient's condition is accompanied by severe diarrhea, an antibiotic is prescribed in a re-oral form. During long-term therapy, it is necessary to constantly monitor, because the risk of developing superinfection increases due to a decrease in sensitivity to amoxicillin in pathogenic microorganisms.

Amoxicillin during pregnancy and lactation

Amoxicillin-based medications are prescribed to pregnant women in cases where the expected benefit to the patient exceeds the possible harm to the fetus.

If you can not do without the use of drugs with antimicrobial effects during breastfeeding, you should consider the issue of a temporary transition to artificial.

Can I drink alcohol while taking the drug?

From the use of alcohol-containing drinks during the treatment with "Amoxicillin" should be abstained. Alcohol increases the likelihood of side effects, creates an additional burden on the liver and kidneys.

Drug Interactions with Other Drugs

As a rule, Amoxicillin combines well with drugs from other pharmacokinetic categories. But still, some combinations can have a negative effect on the patient’s health.

It is not recommended to combine the use of "Amoxicillin" with the use of such drugs:

  • Allopurinol;
  • "Digoxin";
  • anticoagulants;
  • "Probenecid";
  • other antimicrobial drugs;
  • "Methotrexate."

Amoxicillin-based medicines have the ability to reduce the effectiveness of hormonal contraceptives, affecting the concentration of progesterone and estrogen in the blood.

This nuance must be taken into account and use barrier methods of contraception.

Contraindications, side effects and overdose

An absolute contraindication to the use of Amoxicillin is hypersensitivity to substances from the penicillin group. The instructions for use indicate that the drug is contraindicated in children under 3 years of age, however, pediatricians prescribe a medicine for babies from birth, if necessary.

Other contraindications:

  • severe renal failure;
  • violation of the functions of the digestive tract;
  • mononucleosis of an infectious origin;
  • lymphocytic leukemia;
  • bronchial asthma;
  • history of colitis, provoked by the use of antibiotics.

With caution, the drug should be taken by patients who are diagnosed with diabetes, because sucrose is part of the tablets.

Due to the use of Amoxicillin, adverse reactions may develop. If you use the drug for a long time, there is a risk of superinfection when microorganisms develop resistance to the active substance. Isolated cases of anemia, leukopenia and other disorders of the hematopoietic system, which, however, disappear after cessation of therapy, have been recorded. The most common adverse reactions include a feeling of discomfort in the abdomen, flatulence, bloating, diarrhea.

Exceeding the dose of the antibiotic is not accompanied by dangerous manifestations. With a strong overdose, a violation of the water-electrolyte balance, improper functioning of the digestive system can occur. Patients with kidney pathologies have a high risk of crystalluria. The drug has no antidote. Overdose therapy is aimed at eliminating the symptoms and alleviating the patient's condition.

Amoxicillin antibiotic analogues

The range of medications in which amoxicillin acts as the main active ingredient is quite extensive. On the shelves of pharmacies you can find drugs in the form of tablets (250 mg, 500 mg, 1 g), capsules, injection. Analogues of Amoxicillin differ from this drug in composition, price.

In the list of the most popular substitutes, you can include drugs with the following trade names:

  • Ammoxylate;
  • Amoxicillin Ecobol;
  • Ospamox;
  • Tysil
  • "Flemoxin Solutab";
  • Amoksikar;
  • Amoxiclav;
  • "Augmentin" and others.

Positive feedback is left by patients about Flemoxin Solutab. This is a new generation antibiotic that effectively kills pathogenic bacteria that are sensitive to amoxicillin.

An antimicrobial agent has a limited list of contraindications, in rare cases, its use is accompanied by unpleasant manifestations.

It is not necessary to prescribe any means on your own, without consulting a doctor, especially when it comes to treating a child. The choice of the drug and the determination of the dose should be based on the data of clinical tests, the symptoms of the disease. The use of an improper medication or a violation of the dosage regimen can cause unpleasant, and in some cases (for example, anaphylactic shock), even life-threatening consequences.

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