Statistics in recent years indicate an increase in the number of people with blood pressure problems. The sad result of this in some cases is atherosclerosis and coronary artery disease. The drug Amlopidin-Prana can help cope with the problem.
Material Content:
The composition of the drug
According to the spectrum of effects on the body, the drug is a blocker of slow calcium channels. The medication is available only in tablet form. Amlodipine-Prana tablets are dispensed in a dosage of 5 or 10 mg.
The list of substances included in the drug:
- amlodipine (active substance);
- corn flour;
- lactose monohydrate;
- hydroxypropyl methylcellulose;
- a salt of magnesium and stearic acid.
The tablets have a standard round shape, not painted. Each has a division that facilitates the breakdown into smaller doses. In packages, the drug is grouped in 10 units, which are placed in blisters. The general package is made of cardboard, it contains instructions for the use of the drug. It is produced by the Russian pharmaceutical company Pranafarm LLC.
Indications for use of Amlodipine-Prana
Amlodipine is a selective product whose principle of action is based on the effect of BMCC. It stops the slow penetration of calcium ions into the vessels and myocardial cells. The drug helps to expand the lumen of the coronary and peripheral vessels (vasodilating effect).
Experts prescribe Amlodipine-Prana in the following pathological conditions:
- coronary spasm;
- diffuse changes in the myocardium;
- peripheral hemovascular angiospasm;
- lack of oxygen for heart function.
The specific pharmacological effect of Amlodipine on the body is that it promotes the relaxation of smooth muscle vascular tissues. Both pristine and prone to ischemia. Thanks to this, the occurrence of a "robbery effect" is prevented.
A characteristic feature of the effect of the drug on the body is the gradual therapeutic effect, therefore, with a hypertensive crisis it is of little use, since emergency measures are necessary in such a situation.
Most often, Amlodipine-Prana is used for arterial hypertension (essential and symptomatic). The pressure indicator should have a steady increase of more than 140/90 mm RT. Art.
Among the indications for taking the medication, in addition to AH, ischemic heart disease (without a characteristic pain syndrome), heart failure (in a chronic form), variant and angina pectoris.
Instructions for taking and dosage of the drug
The basic regimen recommended by cardiologists for the use of Amlodipine-Prana includes a single dose of tablets. The most suitable time for this is the morning after eating. The drug should be washed down with a sufficient amount of water. The standard dosage is 5 mg, however, it is adjusted depending on the disease diagnosed in the patient, the general state of health and the effect obtained. So, with insufficient exposure, the dose rises to 10 mg per day.
If the purpose of taking the medicine is maintenance therapy, then the base amount is halved, that is, the patient is prescribed only 2.5 mg of the drug.
During the first weeks of taking Amlodipine-Prana, constant monitoring of the patient's blood pressure is necessary.
The use of the drug may cause slight dizziness. Therefore, you should temporarily abandon activities that require focused attention (including driving a vehicle).
During pregnancy and lactation
Amlodipine-Prana is a toxic drug, so its use during the period of gestation is undesirable. However, due to the seriousness of the indications for taking this medicine, it can also be prescribed to a pregnant woman, if the positive effect of the therapy outweighs the potential risk to the fetus.
The active components of the drug penetrate into breast milk, therefore, while using Amlodipine-Prana, breastfeeding is recommended to be stopped. The child on a temporary or permanent basis is transferred to artificial mixtures. If desired, after the end of therapy, breastfeeding can be resumed, however, for this, the woman will have to regularly express during treatment.
Contraindications, side effects and overdose
The use of Amlodipine-Prana has a number of contraindications.
It is prohibited for patients with:
- individual intolerance to the components of the drug;
- unstable angina pectoris;
- lowering blood pressure by more than 20% of the norm;
- aortic stenosis;
- acute vascular insufficiency;
- extreme manifestation of acute heart failure.
In addition, the drug should not be taken by pregnant and lactating women, as well as persons under the age of 18.
The use of Amlodipine-Prana can cause a number of side effects, with varying degrees of severity. They can occur on the part of the cardiovascular system, central nervous system and PNS, respiratory, digestive and hematopoietic organs, the genitourinary system, skin and the musculoskeletal system.
The list of probable adverse reactions:
- swelling of the extremities;
- tachycardia;
- facial redness;
- hypotension;
- development or exacerbation of cardiac dysfunction;
- arteritis;
- syncope;
- migraine;
- sleep disturbance;
- dizziness;
- prostration;
- mood swings and depression;
- loss of sensation;
- numbness of body parts;
- profuse sweating;
- violation of bowel movements;
- increased appetite;
- nausea accompanied by vomiting;
- intestinal cramps;
- increased gas formation;
- dry mouth
- difficulty digestion;
- frequent and painful urination (usually at night);
- sexual dysfunction;
- dyspnea;
- swelling of the nasopharynx;
- allergic dermatosis;
- the formation of age spots;
- itching on the skin;
- allergic conjunctivitis;
- rash in the form of a rash;
- cramps
- muscle and back pain;
- fever;
- osteoarthrosis.
Sometimes, Amlodipine-Prana is accompanied by tinnitus, nosebleeds, visual impairment, gynecomastia.
The likelihood of a negative reaction to the drug increases significantly in case of an overdose. In this case, symptoms such as an excessive decrease in pressure, a deterioration in the blood supply to vital organs, anaphylaxis are observed.
To eliminate the consequences of an overdose for the body that received excessive antihypertensive effects, gastric lavage and sorbent administration are prescribed. Along with this, strict control of the cardiovascular system and respiratory system is necessary. The patient is shown bed rest, in which the position of the limbs of the body should be raised one level above the head. Additionally, vasoconstrictors and intravenous injections of calcium gluconate are prescribed.
Analogs of Amlodipine-Prana
The drug has many analogues. Moreover, as many patients note, some substitutes often cause fewer side effects.
The number of medicines containing the active substance amlodipine includes:
- Norvask
- Amlothop;
- Tenox;
- Kulchek and many others.
These drugs have a similar mechanism of action on the body. However, it is strictly forbidden to start taking one drug instead of another independently, since only the attending physician can predict all the consequences of such a decision.
Despite the high effectiveness of Amlodipine-Prana, it is necessary to obtain specialist advice before taking it. This will minimize the risk of adverse reactions, and will also help determine the most effective treatment regimen.
